{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T02:19:34Z","timestamp":1787019574195,"version":"build-2736575974"},"reference-count":22,"publisher":"European Respiratory Society (ERS)","issue":"6","content-domain":{"domain":["publications.ersnet.org"],"crossmark-restriction":true},"short-container-title":["Eur Respir J"],"accepted":{"date-parts":[[2014,12,8]]},"published-print":{"date-parts":[[2015,6]]},"abstract":"<jats:p>In patients with chronic eosinophilic pneumonia (CEP), dramatic improvements are seen in response to corticosteroid therapy; however, relapse is common after treatment has ceased. The optimal duration of corticosteroid therapy remains unclear.<\/jats:p>\n                  <jats:p>\n                    In a randomised, open-label, parallel group study, eligible patients with CEP received oral prednisolone for either 3\u2005months (3-month group) or 6\u2005months (6-month group), followed by 2\u2005years observation. All patients were treated with an initial dose of prednisolone of 0.5\u2005mg\u00b7kg\n                    <jats:sup>\u22121<\/jats:sup>\n                    \u00b7day\n                    <jats:sup>\u22121<\/jats:sup>\n                    , which was then tapered and discontinued at either 3 or 6\u2005months. The primary end-point was relapse during the follow-up period.\n                  <\/jats:p>\n                  <jats:p>In the final analysis, there were 23 patients in the 3-month group and 21 patients in the 6-month group. All patients showed a good response to prednisolone treatment. There were 12 (52.1%) relapses in the 3-month group and 13 (61.9%) relapses in the 6-month group. No significant difference was found in the cumulative rate of relapse (p=0.56). All relapse cases showed improvement upon resumption of prednisolone treatment.<\/jats:p>\n                  <jats:p>No difference was observed in the rate of relapse between the 3- and 6-month prednisolone treatment groups for patients with CEP.<\/jats:p>","DOI":"10.1183\/09031936.00199614","type":"journal-article","created":{"date-parts":[[2015,1,22]],"date-time":"2015-01-22T23:28:11Z","timestamp":1421969291000},"page":"1624-1631","update-policy":"https:\/\/doi.org\/10.1183\/ers-crossmark-policy","source":"Crossref","is-referenced-by-count":30,"title":["Efficacy of short-term prednisolone treatment in patients with chronic eosinophilic pneumonia"],"prefix":"10.1183","volume":"45","author":[{"given":"Yoshiyuki","family":"Oyama","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomoyuki","family":"Fujisawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dai","family":"Hashimoto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Noriyuki","family":"Enomoto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yutaro","family":"Nakamura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naoki","family":"Inui","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shigeki","family":"Kuroishi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Koshi","family":"Yokomura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mikio","family":"Toyoshima","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takashi","family":"Yamada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toshihiro","family":"Shirai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masafumi","family":"Masuda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kazumasa","family":"Yasuda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroshi","family":"Hayakawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kingo","family":"Chida","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takafumi","family":"Suda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"81","published-online":{"date-parts":[[2015,1,22]]},"reference":[{"key":"2024102023183625000_45.6.1624.1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM196904102801501"},{"key":"2024102023183625000_45.6.1624.2","doi-asserted-by":"publisher","DOI":"10.1097\/00005792-196907000-00001"},{"key":"2024102023183625000_45.6.1624.3","doi-asserted-by":"publisher","DOI":"10.1111\/j.1398-9995.2005.00812.x"},{"key":"2024102023183625000_45.6.1624.4","doi-asserted-by":"publisher","DOI":"10.1055\/s-2006-939516"},{"key":"2024102023183625000_45.6.1624.5","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.150.5.7952571"},{"key":"2024102023183625000_45.6.1624.6","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.176.4.1761053"},{"key":"2024102023183625000_45.6.1624.7","doi-asserted-by":"publisher","DOI":"10.1097\/00004728-199409000-00011"},{"key":"2024102023183625000_45.6.1624.8","doi-asserted-by":"publisher","DOI":"10.1097\/RCT.0b013e3181ae2949"},{"key":"2024102023183625000_45.6.1624.9","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.128.1.1"},{"key":"2024102023183625000_45.6.1624.10","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.216.3.r00se01773"},{"key":"2024102023183625000_45.6.1624.11","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.153.4.727"},{"key":"2024102023183625000_45.6.1624.12","doi-asserted-by":"publisher","DOI":"10.1148\/101.1.57"},{"key":"2024102023183625000_45.6.1624.13","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1097\/00005792-198805000-00002","article-title":"Chronic eosinophilic pneumonia. 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