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Animal fur exposure, cofactors and health outcomes were obtained periodically up to 10\u2005years of age by parental questionnaires. Information on specific IgE to aeroallergens was available at 10\u2005years. Cytokine-producing peripheral T-cells were assessed in a subgroup of children at 2 and 3\u2005years. Confounder-adjusted associations were evaluated using logistic regression analyses.<\/jats:p><jats:p>Sleeping on animal fur was very common (55%). In adjusted logistic regression analyses, sleeping on animal fur was inversely associated with recurrent early wheezing at 4\u2005years (adjusted OR 0.75, 95% CI 0.61\u20130.93) and current asthma at 6\u2005years (adjusted OR 0.56, 95% CI 0.31\u20131.01). Furthermore, sleeping on animal fur during the first 3\u2005months of life was significantly associated with a persistently stimulated interferon-\u03b3 response until the age of 3\u2005years.<\/jats:p><jats:p>Animal fur could be an effective measure of creating environments associated with higher microbial exposure.<\/jats:p>","DOI":"10.1183\/09031936.00204914","type":"journal-article","created":{"date-parts":[[2015,4,3]],"date-time":"2015-04-03T12:54:28Z","timestamp":1428065668000},"page":"107-114","update-policy":"https:\/\/doi.org\/10.1183\/ers-crossmark-policy","source":"Crossref","is-referenced-by-count":9,"title":["Sleeping on animal fur is related to asthma outcomes in later childhood"],"prefix":"10.1183","volume":"46","author":[{"given":"Christina","family":"Tischer","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie","family":"Standl","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Irina","family":"Lehmann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beate","family":"Schaaf","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"von Berg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joachim","family":"Heinrich","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"81","published-online":{"date-parts":[[2015,4,2]]},"reference":[{"key":"2024102023261708000_46.1.107.1","doi-asserted-by":"publisher","DOI":"10.1038\/nri2871"},{"key":"2024102023261708000_46.1.107.2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa020057"},{"key":"2024102023261708000_46.1.107.3","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2222.2012.04002.x"},{"key":"2024102023261708000_46.1.107.4","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2222.2000.00959.x"},{"key":"2024102023261708000_46.1.107.5","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2006.02.002"},{"key":"2024102023261708000_46.1.107.6","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.00118806"},{"key":"2024102023261708000_46.1.107.7","doi-asserted-by":"publisher","DOI":"10.1111\/j.1398-9995.2007.01340.x"},{"key":"2024102023261708000_46.1.107.8","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.00091210"},{"key":"2024102023261708000_46.1.107.9","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2007.03.037"},{"key":"2024102023261708000_46.1.107.10","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.163.2.2002088"},{"key":"2024102023261708000_46.1.107.11","doi-asserted-by":"publisher","DOI":"10.1067\/mai.2002.128948"},{"key":"2024102023261708000_46.1.107.12","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2222.2003.01665.x"},{"key":"2024102023261708000_46.1.107.13","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.00060214"},{"key":"2024102023261708000_46.1.107.14","doi-asserted-by":"publisher","DOI":"10.1111\/j.1462-2920.2008.01723.x"},{"key":"2024102023261708000_46.1.107.15","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2013.11.035"},{"key":"2024102023261708000_46.1.107.16","first-page":"408","article-title":"House dust mite allergen accumulation on sheepskins","volume":"111","author":"Siebers","year":"1998","journal-title":"NZ Med J"},{"key":"2024102023261708000_46.1.107.17","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.02.02322001"},{"key":"2024102023261708000_46.1.107.18","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2004-2521"},{"key":"2024102023261708000_46.1.107.19","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2014.04.018"},{"key":"2024102023261708000_46.1.107.20","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.95.08030483"},{"key":"2024102023261708000_46.1.107.21","doi-asserted-by":"publisher","DOI":"10.1111\/j.1398-9995.2005.00938.x"},{"key":"2024102023261708000_46.1.107.22","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0043214"},{"key":"2024102023261708000_46.1.107.23","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-3038.2009.00890.x"},{"key":"2024102023261708000_46.1.107.24","doi-asserted-by":"publisher","DOI":"10.1067\/mai.2001.119026"},{"key":"2024102023261708000_46.1.107.25","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2222.2003.01642.x"},{"key":"2024102023261708000_46.1.107.26","doi-asserted-by":"publisher","DOI":"10.1034\/j.1399-3038.1999.00033.x"},{"key":"2024102023261708000_46.1.107.27","doi-asserted-by":"publisher","DOI":"10.1111\/j.1445-5994.1994.tb01784.x"},{"key":"2024102023261708000_46.1.107.28","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(02)11025-7"},{"key":"2024102023261708000_46.1.107.29","doi-asserted-by":"crossref","unstructured":"Reponen T . 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