{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T05:45:58Z","timestamp":1777355158101,"version":"3.51.4"},"reference-count":11,"publisher":"European Respiratory Society (ERS)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Eur Respir J"],"accepted":{"date-parts":[[2000,8,4]]},"published-print":{"date-parts":[[2001,3]]},"abstract":"<jats:p>A 32\u2009yr-old nonsmoking male, diagnosed as having X\u2010linked agammaglobulinemia, presented with fever, cough with purulent sputum, a very intense back pain and a mass of 10 centimetres in lower left lobe. Diagnostic evaluation revealed a squamous cell carcinoma with very aggressive metastases at L3. Malignancies are the second leading cause of death in children and adults with congenital immunodeficiency disorders, mostly non-Hodgkin lymphomas and gastric and colon adenocarcinomas, but this is the first report of lung cancer in a patient with X\u2010linked agammaglobulinemia. Lung cancer incidence has been reported to be higher in patients with other diseases of the lung, however, there is no clear evidence of the role of bronchiectasis in developing lung cancer. It is possible that a longer survival for patients with X\u2010LA recently diagnosed, and an association of chronic bronchial infection, could favour the development of pulmonary neoplasm.<\/jats:p>","DOI":"10.1183\/09031936.01.17305700","type":"journal-article","created":{"date-parts":[[2002,7,27]],"date-time":"2002-07-27T12:36:48Z","timestamp":1027773408000},"page":"570-572","source":"Crossref","is-referenced-by-count":18,"title":["X\u2010linked agammaglobulinaemia and squamous lung cancer"],"prefix":"10.1183","volume":"17","author":[{"given":"J.M.","family":"Echave-Sustaeta","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V.","family":"Villena","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Verdugo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"L\u00f3pez-Encuentra","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"de Agust\u00edn","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N.","family":"Alberti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"81","published-online":{"date-parts":[[2001,3,1]]},"reference":[{"key":"2024101808394500000_17.3.570.1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199508173330707"},{"key":"2024101808394500000_17.3.570.2","first-page":"31","volume":"86","year":"1993","journal-title":"Q J Med"},{"key":"2024101808394500000_17.3.570.3","doi-asserted-by":"publisher","DOI":"10.1023\/A:1027382916924"},{"key":"2024101808394500000_17.3.570.4","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(95)70491-4"},{"key":"2024101808394500000_17.3.570.5","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19930901)72:5<1528::AID-CNCR2820720506>3.0.CO;2-V"},{"key":"2024101808394500000_17.3.570.6","first-page":"335","volume":"127","year":"1995","journal-title":"J Pediatr"},{"key":"2024101808394500000_17.3.570.7","first-page":"813","volume":"84","year":"1997","journal-title":"Bull Cancer"},{"key":"2024101808394500000_17.3.570.8","doi-asserted-by":"publisher","DOI":"10.1016\/0140-6736(93)90883-I"},{"key":"2024101808394500000_17.3.570.9","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199110173251603"},{"key":"2024101808394500000_17.3.570.10","first-page":"92","volume":"19","year":"1988","journal-title":"G Chir"},{"key":"2024101808394500000_17.3.570.11","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/S0169-5002(97)00656-9","volume":"17","year":"1997","journal-title":"Lung-Cancer"}],"container-title":["European Respiratory Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1183\/09031936.01.17305700","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,24]],"date-time":"2025-02-24T07:36:20Z","timestamp":1740382580000},"score":1,"resource":{"primary":{"URL":"https:\/\/publications.ersnet.org\/lookup\/doi\/10.1183\/09031936.01.17305700"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001,3]]},"references-count":11,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2001,3,1]]},"published-print":{"date-parts":[[2001,3]]}},"alternative-id":["10.1183\/09031936.01.17305700"],"URL":"https:\/\/doi.org\/10.1183\/09031936.01.17305700","relation":{},"ISSN":["0903-1936","1399-3003"],"issn-type":[{"value":"0903-1936","type":"print"},{"value":"1399-3003","type":"electronic"}],"subject":[],"published":{"date-parts":[[2001,3]]}}}