{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,26]],"date-time":"2026-10-26T04:01:32Z","timestamp":1792987292445,"version":"4.5.0"},"reference-count":35,"publisher":"European Respiratory Society (ERS)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Eur Respir J"],"accepted":{"date-parts":[[2000,11,28]]},"published-print":{"date-parts":[[2001,4]]},"abstract":"<jats:p>Understanding of the elastic pressure\/volume (<jats:italic>P<\/jats:italic><jats:sub>el<\/jats:sub>\/<jats:italic>V<\/jats:italic>) curve is still limited in health and disease. The aim of the present study was to elucidate the<jats:italic>P<\/jats:italic><jats:sub>el<\/jats:sub>\/<jats:italic>V<\/jats:italic>curve and elastance of the respiratory system (<jats:italic>E<\/jats:italic><jats:sub>RS<\/jats:sub>) lung (<jats:italic>E<\/jats:italic><jats:sub>L<\/jats:sub>) and chest wall (<jats:italic>E<\/jats:italic><jats:sub>CW<\/jats:sub>) in healthy pigs.<\/jats:p><jats:p>Six young (20.8\u2005kg) and seven adult (58.9\u2005kg), anaesthetized, paralysed and ventilated pigs were studied.<jats:italic>P<\/jats:italic><jats:sub>el<\/jats:sub>\/<jats:italic>V<\/jats:italic>curves were recorded at zero end-expiratory pressure (ZEEP) and at positive end-expiratory pressure (PEEP) up to 40\u2005cmH<jats:sub>2<\/jats:sub>O with a computer controlled ventilator during an insufflation at a low, constant flow.<\/jats:p><jats:p><jats:italic>P<\/jats:italic><jats:sub>el<\/jats:sub>\/<jats:italic>V<\/jats:italic>curves of the respiratory system showed a complex pattern in both young and adult pigs. During the insufflation,<jats:italic>E<\/jats:italic><jats:sub>RS<\/jats:sub>decreased, increased, fell, and increased again. A second<jats:italic>P<\/jats:italic><jats:sub>el<\/jats:sub>\/<jats:italic>V<\/jats:italic>curve recorded immediately after the first one showed lower elastance and only one early fall in<jats:italic>E<\/jats:italic><jats:sub>RS<\/jats:sub>.<jats:italic>E<\/jats:italic><jats:sub>CW<\/jats:sub>fell over the initial segment and was then nearly stable. Difference between 1st and 2nd curves reflected changes in E<jats:sub>L<\/jats:sub>caused by recruitment during the 1st insufflation. At PEEP, such signs of collapse and recruitment were reduced.<\/jats:p><jats:p>A strong tendency to lung collapse contributes to a complex pattern of elastic pressure\/volume curves. At low volumes and distending pressures the chest wall contributes significantly to changes in respiratory system elastance.<\/jats:p>","DOI":"10.1183\/09031936.01.17407030","type":"journal-article","created":{"date-parts":[[2002,10,11]],"date-time":"2002-10-11T18:37:23Z","timestamp":1034361443000},"page":"703-711","source":"Crossref","is-referenced-by-count":34,"title":["Elastic properties of the lung and the chest wall in young and adult healthy pigs"],"prefix":"10.1183","volume":"17","author":[{"given":"E.","family":"De Robertis","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.M.","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Blomquist","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.L.","family":"Dahm","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Th\u00f6rne","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B.","family":"Jonson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"81","published-online":{"date-parts":[[2001,4,1]]},"reference":[{"key":"2024101808412966000_17.4.703.1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199802053380602"},{"key":"2024101808412966000_17.4.703.2","doi-asserted-by":"publisher","DOI":"10.1378\/chest.86.1.58"},{"key":"2024101808412966000_17.4.703.3","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.149.1.8111581"},{"key":"2024101808412966000_17.4.703.4","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.152.1.7599810"},{"key":"2024101808412966000_17.4.703.5","doi-asserted-by":"crossref","first-page":"1629","DOI":"10.1164\/ajrccm.155.5.9154868","volume":"155","year":"1997","journal-title":"Am J Respir Crit Care Med"},{"key":"2024101808412966000_17.4.703.6","doi-asserted-by":"publisher","DOI":"10.1007\/s001340051026"},{"key":"2024101808412966000_17.4.703.7","doi-asserted-by":"crossref","first-page":"1149","DOI":"10.1111\/j.1399-6576.1998.tb05268.x","volume":"42","year":"1998","journal-title":"Acta Anaesthesiol Scand"},{"key":"2024101808412966000_17.4.703.8","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.158.1.9708049"},{"key":"2024101808412966000_17.4.703.9","first-page":"82","volume":"54","year":"1998","journal-title":"Thorax"},{"key":"2024101808412966000_17.4.703.10","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.159.4.9801088"},{"key":"2024101808412966000_17.4.703.11","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2796.1996.380747000.x"},{"key":"2024101808412966000_17.4.703.12","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1023\/A:1009916905078","volume":"15","year":"1999","journal-title":"J Clin Monit"},{"key":"2024101808412966000_17.4.703.13","unstructured":"Var\u00e9ne P, Jacquemin C. 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