{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,18]],"date-time":"2026-10-18T02:55:16Z","timestamp":1792292116965,"version":"4.4.0"},"reference-count":20,"publisher":"European Respiratory Society (ERS)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Eur Respir J"],"accepted":{"date-parts":[[2002,6,6]]},"published-print":{"date-parts":[[2002,11]]},"abstract":"<jats:p>\n                    Complications of flexible bronchoscopy (FB) were prospectively evaluated during 1,328 diagnostic procedures in children, not in intensive care units. A total 92.8% of the procedures were performed in conscious patients under sedation and 7.2% under deep sedation. Supplementary oxygen was provided in \u223c80% of cases\n                    <jats:italic>via<\/jats:italic>\n                    endoscopic face mask (n=783) or nasal prongs (n=290).\n                  <\/jats:p>\n                  <jats:p>At least one complication was recorded in 91 cases (6.9%). Minor complications (n=69; 5.2%) included moderate and transient episodes of desaturation (n=15), isolated excessive coughing (n=22), excessive nausea reflex with coughing (n=20), transient laryngospasm (n=6) and epistaxis (n=6). Major complications (n=22; 1.7%) included oxygen desaturation to &lt;90%, either isolated (n=10) or associated with laryngospasm (n=6), coughing (n=4), bronchospasm (n=1), and pneumothorax (n=1).<\/jats:p>\n                  <jats:p>\n                    Major complications involving oxygen desaturation were associated with age &lt;2\u2005yrs (13 of 529\n                    <jats:italic>versus<\/jats:italic>\n                    8 of 778) and laryngotracheal abnormalities (7 of 85\n                    <jats:italic>versus<\/jats:italic>\n                    14 of 1,222). The overall frequency of complications was similar in conscious (6.7%) but sedated patients and patients under deep (7.3%) sedation. However, the frequency of transient desaturation was significantly higher in children undergoing FB under deep sedation. Transient fever after bronchoalveolar lavage was observed in 52 of 277 cases (18.8%).\n                  <\/jats:p>\n                  <jats:p>Flexible bronchoscopy is a safe procedure with &lt;2% major complications. Careful analysis of indications and clinical status for each patient, and proper anaesthesia and monitoring during the examination ensure that the procedure is successful, with a minimum of complications.<\/jats:p>","DOI":"10.1183\/09031936.02.02072001","type":"journal-article","created":{"date-parts":[[2002,11,7]],"date-time":"2002-11-07T19:31:11Z","timestamp":1036697471000},"page":"1271-1276","source":"Crossref","is-referenced-by-count":166,"title":["Complications of flexible bronchoscopy\u00a0in children: prospective study of 1,328 procedures"],"prefix":"10.1183","volume":"20","author":[{"given":"J.","family":"de Blic","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V.","family":"Marchac","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Scheinmann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"81","published-online":{"date-parts":[[2002,11,1]]},"reference":[{"key":"2024101809555960000_20.5.1271.1","doi-asserted-by":"publisher","DOI":"10.1002\/1099-0496(200102)31:2<150::AID-PPUL1024>3.0.CO;2-6"},{"key":"2024101809555960000_20.5.1271.2","first-page":"17","volume":"15","year":"2000","journal-title":"Eur Respir J"},{"key":"2024101809555960000_20.5.1271.3","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1016\/S0031-3955(16)34645-4","volume":"31","year":"1984","journal-title":"Pediatr Clin North Am"},{"key":"2024101809555960000_20.5.1271.4","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.97.10081761"},{"key":"2024101809555960000_20.5.1271.5","doi-asserted-by":"publisher","DOI":"10.1378\/chest.98.6.1370"},{"key":"2024101809555960000_20.5.1271.6","doi-asserted-by":"publisher","DOI":"10.1046\/j.1460-9592.1999.00306.x"},{"key":"2024101809555960000_20.5.1271.7","doi-asserted-by":"publisher","DOI":"10.1136\/adc.84.5.423"},{"key":"2024101809555960000_20.5.1271.8","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.1147"},{"key":"2024101809555960000_20.5.1271.9","first-page":"246","volume":"107","year":"1995","journal-title":"Wien Klin Wochenschr"},{"key":"2024101809555960000_20.5.1271.10","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.161.1.9811043"},{"key":"2024101809555960000_20.5.1271.11","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(98)70451-2"},{"key":"2024101809555960000_20.5.1271.12","doi-asserted-by":"publisher","DOI":"10.1378\/chest.99.3.591"},{"key":"2024101809555960000_20.5.1271.13","doi-asserted-by":"publisher","DOI":"10.1016\/0954-6111(94)90025-6"},{"key":"2024101809555960000_20.5.1271.14","doi-asserted-by":"publisher","DOI":"10.1046\/j.1460-9592.2000.00440.x"},{"key":"2024101809555960000_20.5.1271.15","doi-asserted-by":"publisher","DOI":"10.1378\/chest.99.6.1529"},{"key":"2024101809555960000_20.5.1271.16","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.155.5.9154894"},{"key":"2024101809555960000_20.5.1271.17","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1099-0496(199908)28:2<139::AID-PPUL10>3.0.CO;2-2"},{"key":"2024101809555960000_20.5.1271.18","doi-asserted-by":"publisher","DOI":"10.1378\/chest.117.2.573"},{"key":"2024101809555960000_20.5.1271.19","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1016\/S0031-3955(16)38727-2","volume":"41","year":"1994","journal-title":"Pediatr Clin North Am"},{"key":"2024101809555960000_20.5.1271.20","doi-asserted-by":"publisher","DOI":"10.1097\/00008480-199706000-00002"}],"container-title":["European Respiratory Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1183\/09031936.02.02072001","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,24]],"date-time":"2025-02-24T00:43:10Z","timestamp":1740357790000},"score":1,"resource":{"primary":{"URL":"https:\/\/publications.ersnet.org\/lookup\/doi\/10.1183\/09031936.02.02072001"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2002,11]]},"references-count":20,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2002,11,1]]},"published-print":{"date-parts":[[2002,11]]}},"alternative-id":["10.1183\/09031936.02.02072001"],"URL":"https:\/\/doi.org\/10.1183\/09031936.02.02072001","relation":{},"ISSN":["0903-1936","1399-3003"],"issn-type":[{"value":"0903-1936","type":"print"},{"value":"1399-3003","type":"electronic"}],"subject":[],"published":{"date-parts":[[2002,11]]}}}