{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,5]],"date-time":"2026-02-05T10:59:03Z","timestamp":1770289143013,"version":"3.49.0"},"reference-count":19,"publisher":"European Respiratory Society (ERS)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Eur Respir J"],"accepted":{"date-parts":[[2004,6,21]]},"published-print":{"date-parts":[[2004,11]]},"abstract":"<jats:p>The purpose of this study was to evaluate the performance of<jats:sup>18<\/jats:sup>F-fluorodeoxyglucose (<jats:sup>18<\/jats:sup>FDG) imaging<jats:italic>via<\/jats:italic>coincidence detection emission tomography (CDET) in identifying malignant lesions in subjects exposed to asbestos.<\/jats:p><jats:p>A total of 30 patients exposed to asbestos underwent<jats:sup>18<\/jats:sup>FDG-CDET between January 2000 and June 2003. A CDET scan of the thorax and abdomen was performed 60\u2005min after injection of<jats:sup>18<\/jats:sup>FDG in fasting patients, and results were obtained in slices in three axes. The CDET results were compared to those from computed tomography (CT), and pleural or surgical biopsy in patients with positive<jats:sup>18<\/jats:sup>FDG-CDET results.<\/jats:p><jats:p>All primary malignant mesotheliomas accumulated<jats:sup>18<\/jats:sup>FDG (n=6), and, in two patients, CDET findings were superior to those of CT, allowing early detection. In two cases, lung carcinomas with malignant pleural effusion were also detected. There were five false positive CDET results: three unilateral pleural thickening, one rounded atelectasis, and one benign lung nodule. All patients with pleural plaques showed no significant<jats:sup>18<\/jats:sup>FDG uptake. Malignant diseases were detected by<jats:sup>18<\/jats:sup>FDG-CDET imaging with a sensitivity of 89% and specificity of 71%.<\/jats:p><jats:p>Coincidence detection emission tomography can identify malignant mesothelioma in selected subjects exposed to asbestos. Coincidence detection emission tomography appears to be a useful noninvasive method for the follow-up of subjects with exposure risk of asbestosis.<\/jats:p>","DOI":"10.1183\/09031936.04.00004504","type":"journal-article","created":{"date-parts":[[2004,10,31]],"date-time":"2004-10-31T07:42:55Z","timestamp":1099208575000},"page":"814-821","source":"Crossref","is-referenced-by-count":13,"title":["Assessment of<sup>18<\/sup>F-fluorodeoxyglucose dual-head gamma camera in asbestos lung 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