{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,6]],"date-time":"2026-11-06T19:19:51Z","timestamp":1793992791494,"version":"4.8.0"},"reference-count":25,"publisher":"European Respiratory Society (ERS)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Eur Respir J"],"accepted":{"date-parts":[[2004,6,23]]},"published-print":{"date-parts":[[2004,10]]},"abstract":"<jats:p>The usefulness of endobronchial ultrasonography (EBUS) with guide-sheath (GS) as a guide for transbronchial biopsy (TBB) for diagnosing peripheral pulmonary lesions (PPL)s and for improving diagnostic accuracy was evaluated in this study.<\/jats:p><jats:p>EBUS-GS-guided TBB was performed in 24 patients with 24 PPLs of \u226430\u2005mm in diameter (average diameter=18.4\u2005mm). A 20-MHz radial-type ultrasound probe, covered with GS was inserted<jats:italic>via<\/jats:italic>a working bronchoscope channel and advanced to the PPL in order to produce an EBUS image. The probe with the GS was confirmed to reach the lesion by EBUS imaging and X-ray fluoroscopy. When the lesion was not identified on the EBUS image, the probe was removed and a curette was used to lead the GS to the lesion. After localising the lesion, the probe was removed, and TBB and bronchial brushing were performed<jats:italic>via<\/jats:italic>the GS.<\/jats:p><jats:p>Nineteen peripheral lesions (79.2%) were visualised by EBUS. All patients whose PPLs were visible on EBUS images subsequently underwent an EBUS-GS-guided diagnostic procedure. A total of 14 lesions (58.3%) were diagnosed. Even when restricted to PPLs &lt;20\u2005mm in diameter, the diagnostic sensitivity was 53%.<\/jats:p><jats:p>In conclusion, endobronchial ultrasonography with guide sheath-guided transbronchial biopsy was feasible and effective for diagnosing peripheral pulmonary lesions.<\/jats:p>","DOI":"10.1183\/09031936.04.00138603","type":"journal-article","created":{"date-parts":[[2004,9,30]],"date-time":"2004-09-30T21:28:32Z","timestamp":1096579712000},"page":"533-537","source":"Crossref","is-referenced-by-count":180,"title":["Endobronchial ultrasonography with guide-sheath for peripheral pulmonary 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