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Injured and noninjured (control) rat hemidiaphragms were excised at different time points (1\u2013240\u2005h).<\/jats:p><jats:p>In injured hemidiaphragms, in comparison with control muscles, p94 expression levels peaked at 1\u2005h post-injury (PI), cFos mRNA levels began to rise, after an initial dip, and peaked at 96\u2005h PI, while myogenin mRNA levels started to increase as early as 12\u2005h PI, IGF-II mRNA levels initially decreased until 48\u2005h PI and increased thereafter, peaking at 72\u2005h PI, bFGF mRNA levels rose to a maximum at 96\u2005h PI, and MHC and titin mRNA levels were significantly elevated at 72\u2005h PI.<\/jats:p><jats:p>Caffeine-induced diaphragm injury is followed by a time-based expression programme of different genes tailored to meet muscle repair needs.<\/jats:p>","DOI":"10.1183\/09031936.05.00047704","type":"journal-article","created":{"date-parts":[[2005,2,28]],"date-time":"2005-02-28T19:59:19Z","timestamp":1109620759000},"page":"422-430","source":"Crossref","is-referenced-by-count":8,"title":["Time-based gene expression programme following diaphragm injury in a rat model"],"prefix":"10.1183","volume":"25","author":[{"given":"S. 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