{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,21]],"date-time":"2026-03-21T19:46:13Z","timestamp":1774122373110,"version":"3.50.1"},"reference-count":35,"publisher":"European Respiratory Society (ERS)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Eur Respir J"],"accepted":{"date-parts":[[2005,3,22]]},"published-print":{"date-parts":[[2005,7]]},"abstract":"<jats:p>The present study aimed to determine what proportion of children who are in close contact with immigrant tuberculosis (TB) patients are infected with<jats:italic>Mycobacterium tuberculosis<\/jats:italic>.<\/jats:p><jats:p>For 1.5\u2005yrs, 14 municipal health services in the Netherlands collected data from all non-Dutch TB patients and their contacts. Close contacts aged &lt;16\u2005yrs received a tuberculin skin test (TST). A positive TST was defined as an induration of \u226510\u2005mm among nonvaccinated children, and \u226516\u2005mm among bacille Calmette\u2013Gu\u00e9rin-vaccinated children.<\/jats:p><jats:p>In total, 244 patients had 359 close contacts aged &lt;16\u2005yrs. Nine out of the 359 (2.5%) had TB. A TST test was given to 298 out of the 359 (83%). Of the 115 contacts of 44 extrapulmonary TB patients, three (3%) had a positive TST. Of the 186 contacts of 58 positive pulmonary TB patients, 30 (16%) had a positive TST. Contacts of sputum smear-positive patients significantly more often had a positive TST (25%), compared with the contacts of sputum smear-negative patients (7%). Children born abroad significantly more often had a positive TST (20%) than children born in the Netherlands (5%).<\/jats:p><jats:p>In conclusion, the prevalence of active tuberculosis and latent tuberculosis infection among children who are close contacts of immigrant tuberculosis patients is high and warrants an expansion of contact investigation.<\/jats:p>","DOI":"10.1183\/09031936.05.00133204","type":"journal-article","created":{"date-parts":[[2005,7,1]],"date-time":"2005-07-01T02:24:00Z","timestamp":1120184640000},"page":"126-132","source":"Crossref","is-referenced-by-count":13,"title":["Tuberculosis infection in children who are contacts of immigrant tuberculosis patients"],"prefix":"10.1183","volume":"26","author":[{"given":"S.","family":"Verver","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. 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