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Outcomes were asthma-related hospitalisations or emergency department (ED) visits within 6 months following baseline.<\/jats:p><jats:p>Overall, 239 subjects (8.5%) reported hospitalisation or ED visits at follow-up. Predictors retained after multivariate analysis were as follows: younger age; female sex; non-white race; body mass index \u226535 kg\u00b7m<jats:sup>-2<\/jats:sup>; post-bronchodilator per cent predicted forced vital capacity &lt;70%; history of pneumonia; diabetes; cataracts; intubation for asthma; and three or more steroid bursts in the prior 3\u2005months. A final risk score derived from the logistic regression model ranged from 0\u201318 and was highly predictive (c-index: 0.78) of hospitalisation or ED visits. This tool was re-tested in a prospective validation using outcomes at 12- to 18-months follow-up among the same cohort (c-index: 0.77).<\/jats:p><jats:p>The risk score derived is a clinically useful tool for assessing the likelihood of asthma-related hospitalisation or emergency department visits in adults with severe and difficult-to-treat asthma.<\/jats:p>","DOI":"10.1183\/09031936.06.00145105","type":"journal-article","created":{"date-parts":[[2006,7,27]],"date-time":"2006-07-27T00:18:35Z","timestamp":1153959515000},"page":"1145-1155","source":"Crossref","is-referenced-by-count":79,"title":["TENOR risk score predicts healthcare in adults with severe or difficult-to-treat asthma"],"prefix":"10.1183","volume":"28","author":[{"given":"M. K.","family":"Miller","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. H.","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P. 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