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Serum A-FABP levels showed significant positive correlations with duration of oxygen desaturation and minimal oxygen saturation, fasting insulin and insulin resistance index by homeostasis model assessment. When subjects were divided into tertiles according to apnoea\/hypopnoea index (AHI), serum A-FABP levels were significantly higher in the group with AHI \u226534.4\u2005events\u00b7h<jats:sup>\u22121<\/jats:sup>than the groups with AHI 13.2\u201334.4\u2005events\u00b7h<jats:sup>\u22121<\/jats:sup>or with AHI &lt;13.2\u2005events\u00b7h<jats:sup>\u22121<\/jats:sup>. Serum A-FABP levels were significantly higher in the AHI \u226534.4 group than obesity-matched subjects with AHI &lt;34.4\u2005events\u00b7h<jats:sup>\u22121<\/jats:sup>.<\/jats:p><jats:p>Serum adipocyte-fatty acid binding protein levels correlated with obstructive sleep apnoea and insulin resistance, independently of obesity, and were significantly higher in severe obstructive sleep apnoea. Adipocyte-fatty acid binding protein may play a role in obstructive sleep apnoea and metabolic dysfunction.<\/jats:p>","DOI":"10.1183\/09031936.50075408","type":"journal-article","created":{"date-parts":[[2009,1,30]],"date-time":"2009-01-30T20:01:03Z","timestamp":1233345663000},"page":"346-351","source":"Crossref","is-referenced-by-count":28,"title":["Serum adipocyte-fatty acid binding protein level is elevated in severe OSA and correlates with insulin resistance"],"prefix":"10.1183","volume":"33","author":[{"given":"D. C-L.","family":"Lam","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K. 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