{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T22:29:58Z","timestamp":1773354598821,"version":"3.50.1"},"reference-count":0,"publisher":"European Respiratory Society (ERS)","issue":"9","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Eur Respir J"],"published-print":{"date-parts":[[1997,9,1]]},"abstract":"<jats:p>We have previously shown that AutoSet satisfactorily improves sleep-disordered breathing and sleep architecture in subjects with obstructive sleep apnoea (OSA) syndrome. The aim of this study was to determine, in subjects treated with long-term conventional fixed pressure continuous positive airway pressure (CPAP) at the AutoSet recommended pressure, whether: the long-term compliance is satisfactory; the improvement persists once initial rebound is over; the titration pressure is stable with time; and the titration pressure is comparable with manual titration pressure using a similar end-point. Twenty males with OSA, previously studied with full polysomnography on their diagnostic night, at manual and AutoSet titration, and at the AutoSet recommended fixed pressure, were re-studied after a mean of 3 and 8 months of treatment at the recommended fixed pressure. Re-study included home respiratory monitoring (Nellcor EdenTrace), and repeated manual and AutoSet titration with polysomnography. Compliance was assessed with hour-meter readings. Mean (+\/-SEM) usage was 5.7 +\/- 0.1 h.night-1 at 3 and 8 months. The arousal index remained normalized. Diagnostic respiratory disturbance index (RDI) was 60.3 +\/- 5.7 events.h-1. On AutoSet at fixed CPAP, RDI was initially 2.6 +\/- 0.7 events.h-1, then rose slightly (p &lt; 0.001) to 4.3 +\/- 0.6 events.h-1 at 3 months, and was 3.6 +\/- 0.5 events.h-1 at 8 months. AutoSet titration pressure was: 9.9 +\/- 0.4 cmH2O initially, 10.6 +\/- 0.4 cmH2O at 3 months, and 9.7 +\/- 0.5 cmH2O at 8 months (NS). Manual titration pressure at 8 months was 10.4 +\/- 0.4 cmH2O. The standard deviation of the discrepancy with AutoSet was 0.84 cmH2O. In conclusion, the AutoSet recommended pressure varies little with time, and closely predicts the final manual titration pressure; the improvement in respiratory disturbance index was largely maintained, and compliance was good, although probably enhanced by close supervision.<\/jats:p>","DOI":"10.1183\/09031936.97.10092073","type":"journal-article","created":{"date-parts":[[2003,2,14]],"date-time":"2003-02-14T23:54:40Z","timestamp":1045266880000},"page":"2073-2078","source":"Crossref","is-referenced-by-count":61,"title":["AutoSet nasal CPAP titration: constancy of pressure, compliance and effectiveness at 8 month follow-up"],"prefix":"10.1183","volume":"10","author":[{"given":"H","family":"Teschler","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"AA","family":"Farhat","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V","family":"Exner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N","family":"Konietzko","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"Berthon-Jones","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"81","published-online":{"date-parts":[[1997,9,1]]},"container-title":["European Respiratory Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1183\/09031936.97.10092073","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,24]],"date-time":"2025-02-24T07:19:55Z","timestamp":1740381595000},"score":1,"resource":{"primary":{"URL":"https:\/\/publications.ersnet.org\/lookup\/doi\/10.1183\/09031936.97.10092073"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1997,9,1]]},"references-count":0,"journal-issue":{"issue":"9","published-online":{"date-parts":[[1997,9,1]]},"published-print":{"date-parts":[[1997,9,1]]}},"alternative-id":["10.1183\/09031936.97.10092073"],"URL":"https:\/\/doi.org\/10.1183\/09031936.97.10092073","relation":{},"ISSN":["0903-1936","1399-3003"],"issn-type":[{"value":"0903-1936","type":"print"},{"value":"1399-3003","type":"electronic"}],"subject":[],"published":{"date-parts":[[1997,9,1]]}}}