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We aimed to study the relationship between maternal intake of free sugar during pregnancy and respiratory and atopic outcomes in the offspring in a population-based birth cohort, the Avon Longitudinal Study of Parents and Children.<\/jats:p><jats:p>We analysed associations between maternal intake of free sugar in pregnancy (estimated by a food frequency questionnaire), and current doctor-diagnosed asthma, wheezing, hay fever, eczema, atopy, serum total IgE and lung function in children aged 7\u20139\u2005years (n=8956 with information on maternal diet in pregnancy and at least one outcome of interest).<\/jats:p><jats:p>After controlling for potential confounders, maternal intake of free sugar was positively associated with atopy (OR for highest<jats:italic>versus<\/jats:italic>lowest quintile of sugar intake 1.38, 95% CI 1.06\u20131.78; per quintile p-trend=0.006) and atopic asthma (OR 2.01, 95% CI 1.23\u20133.29; per quintile p-trend=0.004). These associations were not confounded by intake of sugar in early childhood, which was unrelated to these outcomes.<\/jats:p><jats:p>Our results suggest that a higher maternal intake of free sugar during pregnancy is associated with an increased risk of atopy and atopic asthma in the offspring, independently of sugar intake in early childhood.<\/jats:p>","DOI":"10.1183\/13993003.00073-2017","type":"journal-article","created":{"date-parts":[[2017,7,6]],"date-time":"2017-07-06T01:10:25Z","timestamp":1499303425000},"page":"1700073","update-policy":"https:\/\/doi.org\/10.1183\/ers-crossmark-policy","source":"Crossref","is-referenced-by-count":76,"title":["Maternal intake of sugar during pregnancy and childhood respiratory and\u00a0atopic outcomes"],"prefix":"10.1183","volume":"50","author":[{"given":"Annabelle","family":"B\u00e9dard","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kate","family":"Northstone","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A. 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