{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T16:05:09Z","timestamp":1790870709359,"version":"4.1.0"},"reference-count":8,"publisher":"European Respiratory Society (ERS)","issue":"5","license":[{"start":{"date-parts":[[2019,2,20]],"date-time":"2019-02-20T00:00:00Z","timestamp":1550620800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.ersjournals.com\/user-licence"}],"funder":[{"DOI":"10.13039\/100007560","name":"Chiesi Farmaceutici","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007560","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["publications.ersnet.org"],"crossmark-restriction":true},"short-container-title":["Eur Respir J"],"accepted":{"date-parts":[[2019,2,12]]},"published-print":{"date-parts":[[2019,5]]},"DOI":"10.1183\/13993003.00235-2019","type":"journal-article","created":{"date-parts":[[2019,2,21]],"date-time":"2019-02-21T12:19:44Z","timestamp":1550751584000},"page":"1900235","update-policy":"https:\/\/doi.org\/10.1183\/ers-crossmark-policy","source":"Crossref","is-referenced-by-count":24,"title":["Extrafine triple therapy in patients with symptomatic COPD and history of one\u00a0moderate exacerbation"],"prefix":"10.1183","volume":"53","author":[{"given":"Dave","family":"Singh","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8894-1689","authenticated-orcid":false,"given":"Leonardo M.","family":"Fabbri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Massimo","family":"Corradi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"George","family":"Georges","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessandro","family":"Guasconi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefano","family":"Vezzoli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefano","family":"Petruzzelli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6924-4500","authenticated-orcid":false,"given":"Alberto","family":"Papi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"81","published-online":{"date-parts":[[2019,2,20]]},"reference":[{"key":"2024102100501888000_53.5.1900235.1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0909883"},{"key":"2024102100501888000_53.5.1900235.2","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1016\/S2213-2600(17)30207-2","article-title":"Frequency of exacerbations in patients with chronic obstructive pulmonary disease: an analysis of the SPIROMICS cohort","volume":"5","author":"Han","year":"2017","journal-title":"Lancet Respir Med"},{"key":"2024102100501888000_53.5.1900235.3","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(16)31354-X"},{"key":"2024102100501888000_53.5.1900235.4","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(17)30188-5"},{"key":"2024102100501888000_53.5.1900235.5","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(18)30206-X"},{"key":"2024102100501888000_53.5.1900235.6","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1713901"},{"key":"2024102100501888000_53.5.1900235.7","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.00214-2017"},{"key":"2024102100501888000_53.5.1900235.8","unstructured":"Global Initiative for Chronic Obstructive Lung Disease . Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Pulmonary Disease. 2019. https:\/\/goldcopd.org Date last accessed: January 24, 2019."}],"container-title":["European Respiratory Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1183\/13993003.00235-2019","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,24]],"date-time":"2025-02-24T07:35:23Z","timestamp":1740382523000},"score":1,"resource":{"primary":{"URL":"https:\/\/publications.ersnet.org\/lookup\/doi\/10.1183\/13993003.00235-2019"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,2,20]]},"references-count":8,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2019,5,18]]},"published-print":{"date-parts":[[2019,5]]}},"alternative-id":["10.1183\/13993003.00235-2019"],"URL":"https:\/\/doi.org\/10.1183\/13993003.00235-2019","relation":{},"ISSN":["0903-1936","1399-3003"],"issn-type":[{"value":"0903-1936","type":"print"},{"value":"1399-3003","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,2,20]]}}}