{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,7]],"date-time":"2026-02-07T12:02:06Z","timestamp":1770465726499,"version":"3.49.0"},"reference-count":27,"publisher":"European Respiratory Society (ERS)","issue":"4","license":[{"start":{"date-parts":[[2023,3,1]],"date-time":"2023-03-01T00:00:00Z","timestamp":1677628800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["publications.ersnet.org"],"crossmark-restriction":true},"short-container-title":["Eur Respir J"],"accepted":{"date-parts":[[2023,2,19]]},"published-print":{"date-parts":[[2023,4]]},"DOI":"10.1183\/13993003.00270-2023","type":"journal-article","created":{"date-parts":[[2023,3,6]],"date-time":"2023-03-06T11:51:19Z","timestamp":1678103479000},"page":"2300270","update-policy":"https:\/\/doi.org\/10.1183\/ers-crossmark-policy","source":"Crossref","is-referenced-by-count":5,"title":["A patient-tailored approach for corticosteroid treatment in COVID-19: still not there yet"],"prefix":"10.1183","volume":"61","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4735-823X","authenticated-orcid":false,"given":"Mattia","family":"Nigro","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James D.","family":"Chalmers","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0090-4531","authenticated-orcid":false,"given":"Stefano","family":"Aliberti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"81","published-online":{"date-parts":[[2023,3,1]]},"reference":[{"key":"2024102103125388000_61.4.2300270.1","unstructured":"World Health Organization . WHO COVID-19 Dashboard. https:\/\/covid19.who.int"},{"key":"2024102103125388000_61.4.2300270.2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(20)30183-5"},{"key":"2024102103125388000_61.4.2300270.3","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra2026131"},{"key":"2024102103125388000_61.4.2300270.4","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2021436"},{"key":"2024102103125388000_61.4.2300270.5","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.00048-2021"},{"key":"2024102103125388000_61.4.2300270.6","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.m3379"},{"key":"2024102103125388000_61.4.2300270.7","unstructured":"National Institute for Health and Care Excellence . COVID-19 Rapid Guideline: Managing COVID-19. Date last updated: 4 January 2023. www.nice.org.uk\/guidance\/ng191\/resources\/covid19-rapid-guideline-managing-covid19-pdf-51035553326"},{"key":"2024102103125388000_61.4.2300270.8","unstructured":"National Institutes of Health . Coronavirus Disease 2019 (COVID-19) Treatment Guidelines. https:\/\/files.covid19treatmentguidelines.nih.gov\/guidelines\/covid19treatmentguidelines.pdf"},{"key":"2024102103125388000_61.4.2300270.9","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1016\/j.cmi.2021.11.007","article-title":"ESCMID COVID-19 living guidelines: drug treatment and clinical management","volume":"28","author":"Bartoletti","year":"2022","journal-title":"Clin Microbiol Infect"},{"key":"2024102103125388000_61.4.2300270.10","doi-asserted-by":"publisher","DOI":"10.4187\/respcare.06314"},{"key":"2024102103125388000_61.4.2300270.11","doi-asserted-by":"crossref","first-page":"1660","DOI":"10.1016\/j.chest.2021.05.024","article-title":"Personalized variable vs fixed-dose systemic corticosteroid therapy in hospitalized patients with acute exacerbations of COPD","volume":"160","author":"Li","year":"2021","journal-title":"Chest"},{"key":"2024102103125388000_61.4.2300270.12","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2021.18295"},{"key":"2024102103125388000_61.4.2300270.13","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.02518-2021"},{"key":"2024102103125388000_61.4.2300270.14","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1177\/08850666211066799","article-title":"High- versus low-dose dexamethasone for the treatment of COVID-19-related acute respiratory distress syndrome: a multicenter, randomized open-label clinical trial","volume":"37","author":"Maskin","year":"2022","journal-title":"J Intensive Care Med"},{"key":"2024102103125388000_61.4.2300270.15","doi-asserted-by":"crossref","first-page":"e0275217","DOI":"10.1371\/journal.pone.0275217","article-title":"Low-dose versus high-dose dexamethasone for hospitalized patients with COVID-19 pneumonia: a randomized clinical trial","volume":"17","author":"Wu","year":"2022","journal-title":"PLoS One"},{"key":"2024102103125388000_61.4.2300270.16","doi-asserted-by":"crossref","first-page":"906","DOI":"10.1001\/jamainternmed.2022.2168","article-title":"High-dose dexamethasone and oxygen support strategies in intensive care unit patients with severe COVID-19 acute hypoxemic respiratory failure","volume":"182","author":"Bouadma","year":"2022","journal-title":"JAMA Intern Med"},{"key":"2024102103125388000_61.4.2300270.17","doi-asserted-by":"crossref","unstructured":"The RECOVERY Collaborative Group , Horby PW , Emberson JR, et al. Higher dose corticosteroids in hospitalised COVID-19 patients with hypoxia but not requiring ventilatory support (RECOVERY): a randomised, controlled, open-label, platform trial. medRxiv 2022; preprint [https:\/\/doi.org\/10.1101\/2022.12.16.22283578]. doi:10.1101\/2022.12.16.22283578","DOI":"10.1101\/2022.12.16.22283578"},{"key":"2024102103125388000_61.4.2300270.18","doi-asserted-by":"crossref","first-page":"2284","DOI":"10.1007\/s00134-020-06289-8","article-title":"Pharmacological principles guiding prolonged glucocorticoid treatment in ARDS","volume":"46","author":"Meduri","year":"2020","journal-title":"Intensive Care Med"},{"key":"2024102103125388000_61.4.2300270.19","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.00025-2022"},{"key":"2024102103125388000_61.4.2300270.20","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1186\/s12879-021-06045-3","article-title":"Methylprednisolone or dexamethasone, which one is superior corticosteroid in the treatment of hospitalized COVID-19 patients: a triple-blinded randomized controlled trial","volume":"21","author":"Ranjbar","year":"2021","journal-title":"BMC Infect Dis"},{"key":"2024102103125388000_61.4.2300270.21","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1186\/s43162-022-00113-z","article-title":"Comparison between methylprednisolone infusion and dexamethasone in COVID-19 ARDS mechanically ventilated patients","volume":"34","author":"Saeed","year":"2022","journal-title":"Egypt J Intern Med"},{"key":"2024102103125388000_61.4.2300270.22","doi-asserted-by":"crossref","first-page":"e13881","DOI":"10.1111\/eci.13881","article-title":"Effect of intravenous pulses of methylprednisolone 250 mg versus dexamethasone 6 mg in hospitalised adults with severe COVID-19 pneumonia: an open-label randomised trial","volume":"53","author":"Corral-Gudino","year":"2023","journal-title":"Eur J Clin Invest"},{"key":"2024102103125388000_61.4.2300270.23","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.01514-2022"},{"key":"2024102103125388000_61.4.2300270.24","doi-asserted-by":"publisher","DOI":"10.1378\/chest.06-2100"},{"key":"2024102103125388000_61.4.2300270.25","doi-asserted-by":"crossref","first-page":"ofaa421","DOI":"10.1093\/ofid\/ofaa421","article-title":"Prolonged low-dose methylprednisolone in patients with severe COVID-19 pneumonia","volume":"7","author":"Salton","year":"2020","journal-title":"Open Forum Infect Dis"},{"key":"2024102103125388000_61.4.2300270.26","doi-asserted-by":"crossref","first-page":"1009","DOI":"10.1007\/s00134-022-06684-3","article-title":"Low-dose methylprednisolone treatment in critically ill patients with severe community-acquired pneumonia","volume":"48","author":"Meduri","year":"2022","journal-title":"Intensive Care Med"},{"key":"2024102103125388000_61.4.2300270.27","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMe048225"}],"container-title":["European Respiratory Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1183\/13993003.00270-2023","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,24]],"date-time":"2025-02-24T06:21:23Z","timestamp":1740378083000},"score":1,"resource":{"primary":{"URL":"https:\/\/publications.ersnet.org\/lookup\/doi\/10.1183\/13993003.00270-2023"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,3,1]]},"references-count":27,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2023,4,20]]},"published-print":{"date-parts":[[2023,4]]}},"alternative-id":["10.1183\/13993003.00270-2023"],"URL":"https:\/\/doi.org\/10.1183\/13993003.00270-2023","relation":{},"ISSN":["0903-1936","1399-3003"],"issn-type":[{"value":"0903-1936","type":"print"},{"value":"1399-3003","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,3,1]]}}}