{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T00:33:14Z","timestamp":1787790794271,"version":"build-2784847793"},"reference-count":20,"publisher":"European Respiratory Society (ERS)","issue":"1","license":[{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003107","name":"Bundesministerium f\u00fcr Gesundheit","doi-asserted-by":"publisher","award":["ZMVI1-2519GHP708"],"award-info":[{"award-number":["ZMVI1-2519GHP708"]}],"id":[{"id":"10.13039\/501100003107","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","award":["EXC 2167"],"award-info":[{"award-number":["EXC 2167"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","award":["Leibniz Science Campus Evolutionary Medicine of th"],"award-info":[{"award-number":["Leibniz Science Campus Evolutionary Medicine of th"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","award":["Research Training Group 2501 TransEvo"],"award-info":[{"award-number":["Research Training Group 2501 TransEvo"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["NIAID R01-AI176498"],"award-info":[{"award-number":["NIAID R01-AI176498"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01-AI155765"],"award-info":[{"award-number":["R01-AI155765"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002913","name":"Vlaamse Overheid","doi-asserted-by":"publisher","award":["G0B0222N"],"award-info":[{"award-number":["G0B0222N"]}],"id":[{"id":"10.13039\/501100002913","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["publications.ersnet.org"],"crossmark-restriction":true},"short-container-title":["Eur Respir J"],"accepted":{"date-parts":[[2024,5,6]]},"published-print":{"date-parts":[[2024,7]]},"DOI":"10.1183\/13993003.00391-2024","type":"journal-article","created":{"date-parts":[[2024,7,11]],"date-time":"2024-07-11T09:30:40Z","timestamp":1720690240000},"page":"2400391","update-policy":"https:\/\/doi.org\/10.1183\/ers-crossmark-policy","source":"Crossref","is-referenced-by-count":17,"title":["A composite reference standard is needed for bedaquiline antimicrobial susceptibility testing for<i>Mycobacterium tuberculosis<\/i>complex"],"prefix":"10.1183","volume":"64","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0232-846X","authenticated-orcid":false,"given":"Claudio U.","family":"K\u00f6ser","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4610-2427","authenticated-orcid":false,"given":"Paolo","family":"Miotto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2287-1857","authenticated-orcid":false,"given":"Nabila","family":"Ismail","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0550-5273","authenticated-orcid":false,"given":"Richard M.","family":"Anthony","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Utpatel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1386-2331","authenticated-orcid":false,"given":"Matthias","family":"Merker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6604-0684","authenticated-orcid":false,"given":"Stefan","family":"Niemann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6887-8149","authenticated-orcid":false,"given":"Sabira","family":"Tahseen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leen","family":"Rigouts","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Camilla","family":"Rodrigues","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6983-1636","authenticated-orcid":false,"given":"Shaheed V.","family":"Omar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3871-5760","authenticated-orcid":false,"given":"Maha R.","family":"Farhat","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Uladzimir","family":"Antonenka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4886-5022","authenticated-orcid":false,"given":"Harald","family":"Hoffmann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6415-1535","authenticated-orcid":false,"given":"Daniela M.","family":"Cirillo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Sch\u00f6n","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"81","published-online":{"date-parts":[[2024,7,11]]},"reference":[{"key":"2024102017314409000_64.1.2400391.1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmoldx.2022.07.005"},{"key":"2024102017314409000_64.1.2400391.2","doi-asserted-by":"crossref","first-page":"2300639","DOI":"10.1183\/13993003.00639-2023","article-title":"Baseline and treatment-emergent bedaquiline resistance in drug-resistant tuberculosis: a systematic review and meta-analysis","volume":"62","author":"Perumal","year":"2024","journal-title":"Eur Respir J"},{"key":"2024102017314409000_64.1.2400391.3","unstructured":"World Health Organization . Catalogue of mutations in Mycobacterium tuberculosis complex and their association with drug resistance, 2nd ed. Geneva, World Health Organization, 2023. https:\/\/iris.who.int\/handle\/10665\/374061"},{"key":"2024102017314409000_64.1.2400391.4","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.00426-2023"},{"key":"2024102017314409000_64.1.2400391.5","unstructured":"World Health Organization . Optimized broth microdilution plate methodology for drug susceptibility testing of Mycobacterium tuberculosis complex. Geneva, World Health Organization, 2022. https:\/\/iris.who.int\/handle\/10665\/353066"},{"key":"2024102017314409000_64.1.2400391.6","unstructured":"World Health Organization . Technical report on critical concentrations for drug susceptibility testing of medicines used in the treatment of drug-resistant tuberculosis. Geneva, World Health Organization, 2018. https:\/\/iris.who.int\/handle\/10665\/260470"},{"key":"2024102017314409000_64.1.2400391.7","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmi.2020.07.037"},{"key":"2024102017314409000_64.1.2400391.8","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.00166-2022"},{"key":"2024102017314409000_64.1.2400391.9","doi-asserted-by":"crossref","first-page":"e0002283","DOI":"10.1371\/journal.pgph.0002283","article-title":"Baseline and acquired resistance to bedaquiline, linezolid and pretomanid, and impact on treatment outcomes in four tuberculosis clinical trials containing pretomanid","volume":"3","author":"Timm","year":"2023","journal-title":"PLoS Glob Public Health"},{"key":"2024102017314409000_64.1.2400391.10","doi-asserted-by":"crossref","first-page":"e0010022","DOI":"10.1128\/cmr.00100-22","article-title":"Wild-type distributions of minimum inhibitory concentrations and epidemiological cut-off values-laboratory and clinical utility","volume":"36","author":"Kahlmeter","year":"2023","journal-title":"Clin Microbiol Rev"},{"key":"2024102017314409000_64.1.2400391.11","doi-asserted-by":"crossref","first-page":"e0291920","DOI":"10.1128\/JCM.02919-20","article-title":"Bedaquiline drug resistance emergence assessment in multidrug-resistant tuberculosis (MDR-TB): a 5-year prospective in vitro surveillance study of bedaquiline and other second-line drug susceptibility testing in MDR-TB isolates","volume":"60","author":"Kaniga","year":"2022","journal-title":"J Clin Microbiol"},{"key":"2024102017314409000_64.1.2400391.12","doi-asserted-by":"crossref","first-page":"791","DOI":"10.5588\/ijtld.21.0428","article-title":"Guidance is needed to mitigate the consequences of analytic errors during antimicrobial susceptibility testing for TB","volume":"25","author":"K\u00f6ser","year":"2021","journal-title":"Int J Tuberc Lung Dis"},{"key":"2024102017314409000_64.1.2400391.13","doi-asserted-by":"crossref","first-page":"e358","DOI":"10.1016\/S2666-5247(23)00002-2","article-title":"Bedaquiline and clofazimine resistance in Mycobacterium tuberculosis: an in-vitro and in-silico data analysis","volume":"4","author":"Sonnenkalb","year":"2023","journal-title":"Lancet Microbe"},{"key":"2024102017314409000_64.1.2400391.14","doi-asserted-by":"crossref","unstructured":"Phelan JE , Utpatel C , Ismail N , et al. Careful classification of potential bedaquiline resistance mutations is critical when analysing their clinical impact. Int J Tuberc Lung Dis 2024; in press [https:\/\/doi.org\/10.5588\/ijtld.24.0083].doi:10.5588\/ijtld.24.0083","DOI":"10.5588\/ijtld.24.0083"},{"key":"2024102017314409000_64.1.2400391.15","doi-asserted-by":"publisher","DOI":"10.1186\/s13073-020-00793-8"},{"key":"2024102017314409000_64.1.2400391.16","first-page":"S226","article-title":"The benefit of targeted next-generation sequencing for the treatment of patients diagnosed with drug-resistant TB in Eswatini [abstract OA18-345-16]","volume":"27","author":"Vambe","year":"2023","journal-title":"Int J Tuberc Lung Dis"},{"key":"2024102017314409000_64.1.2400391.17","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1186\/s13073-024-01311-w","article-title":"The exceptions that prove the rule\u2014a historical view of bedaquiline susceptibility","volume":"16","author":"Miotto","year":"2024","journal-title":"Genome Med"},{"key":"2024102017314409000_64.1.2400391.18","doi-asserted-by":"crossref","first-page":"102747","DOI":"10.1016\/j.ebiom.2020.102747","article-title":"Dynamics of within-host Mycobacterium tuberculosis diversity and heteroresistance during treatment","volume":"55","author":"Nimmo","year":"2020","journal-title":"EBioMedicine"},{"key":"2024102017314409000_64.1.2400391.19","doi-asserted-by":"publisher","DOI":"10.1136\/thorax-2024-221409"},{"key":"2024102017314409000_64.1.2400391.20","doi-asserted-by":"crossref","unstructured":"Ofori-Anyinam N , Hamblin M , Coldren ML , et al. KatG catalase deficiency confers bedaquiline hyper-susceptibility to isoniazid resistant Mycobacterium tuberculosis . bioRxiv 2023; preprint [https:\/\/doi.org\/10.1101\/2023.10.17.562707].","DOI":"10.1101\/2023.10.17.562707"}],"container-title":["European Respiratory Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1183\/13993003.00391-2024","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,24]],"date-time":"2025-02-24T07:21:24Z","timestamp":1740381684000},"score":1,"resource":{"primary":{"URL":"https:\/\/publications.ersnet.org\/lookup\/doi\/10.1183\/13993003.00391-2024"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,7]]},"references-count":20,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2024,7,11]]},"published-print":{"date-parts":[[2024,7]]}},"alternative-id":["10.1183\/13993003.00391-2024"],"URL":"https:\/\/doi.org\/10.1183\/13993003.00391-2024","relation":{},"ISSN":["0903-1936","1399-3003"],"issn-type":[{"value":"0903-1936","type":"print"},{"value":"1399-3003","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,7]]}}}