{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T07:25:20Z","timestamp":1778570720594,"version":"3.51.4"},"reference-count":34,"publisher":"European Respiratory Society (ERS)","issue":"5","license":[{"start":{"date-parts":[[2019,9,19]],"date-time":"2019-09-19T00:00:00Z","timestamp":1568851200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.ersjournals.com\/user-licence"}],"funder":[{"DOI":"10.13039\/501100001826","name":"ZonMw","doi-asserted-by":"publisher","award":["50-53000-98-128"],"award-info":[{"award-number":["50-53000-98-128"]}],"id":[{"id":"10.13039\/501100001826","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["publications.ersnet.org"],"crossmark-restriction":true},"short-container-title":["Eur Respir J"],"accepted":{"date-parts":[[2019,8,26]]},"published-print":{"date-parts":[[2019,11]]},"abstract":"<jats:sec><jats:title>Introduction<\/jats:title><jats:p>Evidence on conditions for implementation of latent tuberculosis infection (LTBI) screening and treatment among asylum seekers is needed to inform tuberculosis (TB) control policies. We used mixed-methods to evaluate the implementation of an LTBI screening and treatment programme among asylum seekers in the Netherlands.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We offered voluntary LTBI screening to asylum seekers aged \u226512\u2005years living in asylum seeker centres from countries with a TB incidence &gt;200 per 10\u200a000 population. We calculated LTBI screening and treatment cascade coverage, and assessed associated factors with Poisson regression using robust variance estimators. We interviewed TB care staff (seven group interviews) and Eritrean clients (21 group and 21 individual interviews) to identify programme enhancers and barriers.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>We screened 719 (63% of 1136) clients for LTBI. LTBI was diagnosed among 178 (25%) clients; 149 (84%) initiated LTBI treatment, of whom 129 (87%) completed treatment. In-person TB and LTBI education, the use of professional interpreters, and collaboration with partner organisations were enhancers for LTBI screening uptake. Demand-driven LTBI treatment support by TB nurses enhanced treatment completion. Factors complicating LTBI screening and treatment were having to travel to public health services, language barriers and moving from asylum seeker centres to the community during treatment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>LTBI screening and treatment of asylum seekers is feasible and effective when high quality of care is provided, including culture-sensitive TB education throughout the care cascade. Additionally, collaboration with partner organisations, such as agencies responsible for reception and support of asylum seekers, should be in place.<\/jats:p><\/jats:sec>","DOI":"10.1183\/13993003.00861-2019","type":"journal-article","created":{"date-parts":[[2019,9,19]],"date-time":"2019-09-19T18:55:11Z","timestamp":1568919311000},"page":"1900861","update-policy":"https:\/\/doi.org\/10.1183\/ers-crossmark-policy","source":"Crossref","is-referenced-by-count":27,"title":["Latent tuberculosis screening and treatment among asylum seekers: a mixed-methods study"],"prefix":"10.1183","volume":"54","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9190-2696","authenticated-orcid":false,"given":"Ineke","family":"Spruijt","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dawit","family":"Tesfay Haile","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeanine","family":"Suurmond","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Susan","family":"van den Hof","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marga","family":"Koenders","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"Kouw","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Natascha","family":"van Noort","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sophie","family":"Toumanian","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Frank","family":"Cobelens","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Simone","family":"Goosen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Connie","family":"Erkens","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"81","published-online":{"date-parts":[[2019,9,19]]},"reference":[{"key":"2024102101090342000_54.5.1900861.1","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.00591-2018"},{"key":"2024102101090342000_54.5.1900861.2","unstructured":"van den Boogaard J , Slump E , Schimmel HJ , et al. Hoge TBC-incidentie bij Eritrese en Somalische asielzoekers in de eerste vijf jaar na aankomst. [High incidence of active tuberculosis in Eritrean and Somalian asylum seekers in the first five years after arrival in the Netherlands: time for a screening programme for latent infection.] Bilthoven, Rijksinstituut voor Volksgezondheid en Milieu, 2018."},{"key":"2024102101090342000_54.5.1900861.3","doi-asserted-by":"crossref","unstructured":"de Vries G , Riesmeijer R . Nationaal Plan Tuberculosebestrijding 2016\u20132020. Op weg naar eliminatie. [National Plan TB Control 2016\u20132020. Towards elimination.] Bilthoven, Rijksinstituut voor Volksgezondheid en Milieu, 2016.","DOI":"10.1007\/s12508-017-0074-1"},{"key":"2024102101090342000_54.5.1900861.4","unstructured":"Slump E , Bregman IM , Erkens CGM , et al. Tuberculose in Nederland 2016. Surveillancerapport. [Tuberculosis in the Netherlands 2016. 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