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On assessing TAA with regard to normalisation of clinical polysomnography findings at follow-up, TAA was reduced in children who had surgical resolution of OSAS (based on apnoea\u2013hypopnoea index), but not in children who displayed spontaneous normalisation of apnoea\u2013hypopnoea index. In the latter group, TAA was inversely correlated with quality of life.<\/jats:p><jats:p>We conclude that adenotonsillectomy reduces TAA during quiet sleep. Monitoring of instantaneous TAA may yield additional insight in the dynamic changes of inspiratory effort. In combination with traditional indices of obstruction, TAA may more accurately characterise the degree of sleep-disordered breathing in children.<\/jats:p>","DOI":"10.1183\/13993003.01177-2016","type":"journal-article","created":{"date-parts":[[2016,11,4]],"date-time":"2016-11-04T01:10:50Z","timestamp":1478221850000},"page":"1601177","update-policy":"https:\/\/doi.org\/10.1183\/ers-crossmark-policy","source":"Crossref","is-referenced-by-count":14,"title":["Adenotonsillectomy for childhood obstructive sleep apnoea reduces thoraco-abdominal asynchrony but spontaneous apnoea\u2212hypopnoea index normalisation does not"],"prefix":"10.1183","volume":"49","author":[{"given":"Xiao","family":"Liu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah","family":"Immanuel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yvonne","family":"Pamula","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Declan","family":"Kennedy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James","family":"Martin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mathias","family":"Baumert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"81","published-online":{"date-parts":[[2016,11,3]]},"reference":[{"key":"2024102100152195000_49.1.1601177.1","doi-asserted-by":"publisher","DOI":"10.1513\/pats.200708-135MG"},{"key":"2024102100152195000_49.1.1601177.2","doi-asserted-by":"publisher","DOI":"10.1016\/j.smrv.2013.04.006"},{"key":"2024102100152195000_49.1.1601177.3","doi-asserted-by":"publisher","DOI":"10.1183\/23120541.00003-2016"},{"key":"2024102100152195000_49.1.1601177.4","doi-asserted-by":"publisher","DOI":"10.1016\/j.otohns.2006.02.033"},{"key":"2024102100152195000_49.1.1601177.5","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.200912-1930OC"},{"key":"2024102100152195000_49.1.1601177.6","doi-asserted-by":"publisher","DOI":"10.1016\/j.otohns.2008.12.038"},{"key":"2024102100152195000_49.1.1601177.7","doi-asserted-by":"publisher","DOI":"10.1378\/chest.15-1319"},{"key":"2024102100152195000_49.1.1601177.8","doi-asserted-by":"publisher","DOI":"10.1378\/chest.14-2261"},{"key":"2024102100152195000_49.1.1601177.9","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.1950190305"},{"key":"2024102100152195000_49.1.1601177.10","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1215881"},{"key":"2024102100152195000_49.1.1601177.11","doi-asserted-by":"crossref","first-page":"1509","DOI":"10.5665\/sleep.1388","article-title":"The Childhood Adenotonsillectomy Trial (CHAT): rationale, design, and challenges of a randomized controlled trial evaluating a standard surgical procedure in a pediatric population","volume":"34","author":"Redline","year":"2011","journal-title":"Sleep"},{"key":"2024102100152195000_49.1.1601177.12","doi-asserted-by":"crossref","first-page":"597","DOI":"10.5664\/jcsm.2172","article-title":"Rules for scoring respiratory events in sleep: update of the 2007 AASM Manual for the Scoring of Sleep and Associated Events. 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