{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T22:20:47Z","timestamp":1791930047933,"version":"4.3.4"},"reference-count":35,"publisher":"European Respiratory Society (ERS)","issue":"2","content-domain":{"domain":["publications.ersnet.org"],"crossmark-restriction":true},"short-container-title":["Eur Respir J"],"accepted":{"date-parts":[[2018,6,6]]},"published-print":{"date-parts":[[2018,8]]},"abstract":"<jats:p>\n                    <jats:italic>Pseudomonas aeruginosa<\/jats:italic>\n                    is a challenging bacterium to treat due to its intrinsic resistance to the antibiotics used most frequently in patients with community-acquired pneumonia (CAP). Data about the global burden and risk factors associated with\n                    <jats:italic>P.\u00a0aeruginosa<\/jats:italic>\n                    -CAP are limited. We assessed the multinational burden and specific risk factors associated with\n                    <jats:italic>P.\u00a0aeruginosa-<\/jats:italic>\n                    CAP.\n                  <\/jats:p>\n                  <jats:p>\n                    We enrolled 3193 patients in 54 countries with confirmed diagnosis of CAP who underwent microbiological testing at admission. Prevalence was calculated according to the identification of\n                    <jats:italic>P.\u00a0aeruginosa<\/jats:italic>\n                    . Logistic regression analysis was used to identify risk factors for antibiotic-susceptible and antibiotic-resistant\n                    <jats:italic>P.\u00a0aeruginosa-<\/jats:italic>\n                    CAP.\n                  <\/jats:p>\n                  <jats:p>\n                    The prevalence of\n                    <jats:italic>P.\u00a0aeruginosa<\/jats:italic>\n                    and antibiotic-resistant\n                    <jats:italic>P.\u00a0aeruginosa-<\/jats:italic>\n                    CAP was 4.2% and 2.0%, respectively. The rate of\n                    <jats:italic>P.\u00a0aeruginosa<\/jats:italic>\n                    CAP in patients with prior infection\/colonisation due to\n                    <jats:italic>P.\u00a0aeruginosa<\/jats:italic>\n                    and at least one of the three independently associated chronic lung diseases (\n                    <jats:italic>i.e.<\/jats:italic>\n                    tracheostomy, bronchiectasis and\/or very severe chronic obstructive pulmonary disease) was 67%. In contrast, the rate of\n                    <jats:italic>P.\u00a0aeruginosa-<\/jats:italic>\n                    CAP was 2% in patients without prior\n                    <jats:italic>P.\u00a0aeruginosa<\/jats:italic>\n                    infection\/colonisation and none of the selected chronic lung diseases.\n                  <\/jats:p>\n                  <jats:p>\n                    The multinational prevalence of\n                    <jats:italic>P.\u00a0aeruginosa-<\/jats:italic>\n                    CAP is low. The risk factors identified in this study may guide healthcare professionals in deciding empirical antibiotic coverage for CAP patients.\n                  <\/jats:p>","DOI":"10.1183\/13993003.01190-2017","type":"journal-article","created":{"date-parts":[[2018,7,5]],"date-time":"2018-07-05T10:25:36Z","timestamp":1530786336000},"page":"1701190","update-policy":"https:\/\/doi.org\/10.1183\/ers-crossmark-policy","source":"Crossref","is-referenced-by-count":191,"title":["Burden and risk factors for\n                    <i>Pseudomonas aeruginosa<\/i>\n                    community-acquired pneumonia: a multinational point prevalence study of hospitalised patients"],"prefix":"10.1183","volume":"52","author":[{"given":"Marcos I.","family":"Restrepo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bettina L.","family":"Babu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luis F.","family":"Reyes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James D.","family":"Chalmers","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nilam J.","family":"Soni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4833-6713","authenticated-orcid":false,"given":"Oriol","family":"Sibila","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paola","family":"Faverio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4646-9838","authenticated-orcid":false,"given":"Catia","family":"Cilloniz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William","family":"Rodriguez-Cintron","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0090-4531","authenticated-orcid":false,"given":"Stefano","family":"Aliberti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"81","published-online":{"date-parts":[[2018,7,5]]},"reference":[{"key":"2024102100314023000_52.2.1701190.1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(15)60733-4"},{"key":"2024102100314023000_52.2.1701190.2","unstructured":"World Health Organization. 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