{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T02:25:36Z","timestamp":1790735136273,"version":"4.1.0"},"reference-count":135,"publisher":"European Respiratory Society (ERS)","issue":"4","license":[{"start":{"date-parts":[[2024,8,29]],"date-time":"2024-08-29T00:00:00Z","timestamp":1724889600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["publications.ersnet.org"],"crossmark-restriction":true},"short-container-title":["Eur Respir J"],"accepted":{"date-parts":[[2024,6,20]]},"published-print":{"date-parts":[[2024,10]]},"abstract":"<jats:p>Despite the progress made in medical therapies for treating pulmonary hypertension (PH), a subset of patients remain susceptible to developing a maladaptive right ventricular phenotype. The effective management of end-stage PH presents substantial challenges, necessitating a multidisciplinary approach and early identification of patients prone to acute decompensation. Identifying potential transplant candidates and assessing the feasibility of such a procedure are pivotal tasks that should be undertaken early in the treatment algorithm. Inclusion on the transplant list is contingent upon a comprehensive risk assessment, also considering the specific type of PH and various factors affecting waiting times, all of which should inform the decision-making process. While bilateral lung transplantation is the preferred option, it demands expert intra- and post-operative management to mitigate the heightened risks of pulmonary oedema and primary graft dysfunction in PH patients. Despite the availability of risk assessment tools, the occurrence of acute PH decompensation episodes can be unpredictable, potentially leading to refractory right ventricular failure even with optimal medical intervention, necessitating the use of rescue therapies. Advancements in right ventricular assist techniques and adjustments to graft allocation protocols for the most critically ill patients have significantly enhanced the survival in intensive care, affording the opportunity to endure while awaiting an urgent transplant. Given the breadth of therapeutic options available, specialised centres capable of delivering comprehensive care have become indispensable for optimising patient outcomes. These centres are instrumental in providing holistic support and management tailored to the complex needs of PH patients, ultimately enhancing their chances of a successful transplant and improved long-term prognosis.<\/jats:p>","DOI":"10.1183\/13993003.01193-2024","type":"journal-article","created":{"date-parts":[[2024,8,29]],"date-time":"2024-08-29T09:28:10Z","timestamp":1724923690000},"page":"2401193","update-policy":"https:\/\/doi.org\/10.1183\/ers-crossmark-policy","source":"Crossref","is-referenced-by-count":44,"title":["Transplantation, bridging, and support technologies in pulmonary hypertension"],"prefix":"10.1183","volume":"64","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6862-8975","authenticated-orcid":false,"given":"Laurent","family":"Savale","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3549-4720","authenticated-orcid":false,"given":"Alberto","family":"Benazzo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul","family":"Corris","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4547-8094","authenticated-orcid":false,"given":"Shaf","family":"Keshavjee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deborah Jo","family":"Levine","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olaf","family":"Mercier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R. Duane","family":"Davis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John T.","family":"Granton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"81","published-online":{"date-parts":[[2024,8,29]]},"reference":[{"key":"2024112623020512000_64.4.2401193.1","doi-asserted-by":"publisher","DOI":"10.1183\/23120541.00002-2022"},{"key":"2024112623020512000_64.4.2401193.2","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.00466-2021"},{"key":"2024112623020512000_64.4.2401193.3","doi-asserted-by":"crossref","first-page":"106685","DOI":"10.1016\/j.rmed.2021.106685","article-title":"Outcomes and prognostic factors of decompensated pulmonary hypertension in the intensive care unit","volume":"190","author":"Garcia","year":"2021","journal-title":"Respir Med"},{"key":"2024112623020512000_64.4.2401193.4","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrc.2012.08.006"},{"key":"2024112623020512000_64.4.2401193.5","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.00148310"},{"key":"2024112623020512000_64.4.2401193.6","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.00070209"},{"key":"2024112623020512000_64.4.2401193.7","doi-asserted-by":"publisher","DOI":"10.1183\/23120541.00046-2021"},{"key":"2024112623020512000_64.4.2401193.8","doi-asserted-by":"crossref","first-page":"1801906","DOI":"10.1183\/13993003.01906-2018","article-title":"Intensive care, right ventricular support and lung transplantation in patients with pulmonary hypertension","volume":"53","author":"Hoeper","year":"2018","journal-title":"Eur Respir J"},{"key":"2024112623020512000_64.4.2401193.9","doi-asserted-by":"crossref","first-page":"762","DOI":"10.1055\/s-0043-1770119","article-title":"Management of acutely decompensated pulmonary hypertension","volume":"44","author":"Savale","year":"2023","journal-title":"Semin Respir Crit Care Med"},{"key":"2024112623020512000_64.4.2401193.10","doi-asserted-by":"crossref","first-page":"1801900","DOI":"10.1183\/13993003.01900-2018","article-title":"Pathophysiology of the right ventricle and of the pulmonary circulation in pulmonary hypertension: an update","volume":"53","author":"Vonk Noordegraaf","year":"2018","journal-title":"Eur Respir J"},{"key":"2024112623020512000_64.4.2401193.11","doi-asserted-by":"crossref","first-page":"1111","DOI":"10.1056\/NEJMra2207410","article-title":"Right ventricular failure","volume":"388","author":"Houston","year":"2023","journal-title":"N Engl J Med"},{"key":"2024112623020512000_64.4.2401193.12","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.116.022362"},{"key":"2024112623020512000_64.4.2401193.13","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-008-1017-8"},{"key":"2024112623020512000_64.4.2401193.14","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2020.06.070"},{"key":"2024112623020512000_64.4.2401193.15","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1159\/000487198","article-title":"Presence of kidney disease as an outcome predictor in patients with pulmonary arterial hypertension","volume":"47","author":"Bitker","year":"2018","journal-title":"Am J Nephrol"},{"key":"2024112623020512000_64.4.2401193.16","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2008.05.068"},{"key":"2024112623020512000_64.4.2401193.17","doi-asserted-by":"crossref","first-page":"771","DOI":"10.1055\/s-0043-1772752","article-title":"Extracorporeal life support in pulmonary hypertension: practical aspects","volume":"44","author":"Hoeper","year":"2023","journal-title":"Semin Respir Crit Care Med"},{"key":"2024112623020512000_64.4.2401193.18","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.116.025290"},{"key":"2024112623020512000_64.4.2401193.19","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.114.012593"},{"key":"2024112623020512000_64.4.2401193.20","doi-asserted-by":"crossref","first-page":"1275","DOI":"10.1016\/j.healun.2019.09.004","article-title":"Extracorporeal life support bridge for pulmonary hypertension: a high-volume single-center experience","volume":"38","author":"Rosenzweig","year":"2019","journal-title":"J Heart Lung Transplant"},{"key":"2024112623020512000_64.4.2401193.21","doi-asserted-by":"crossref","first-page":"404","DOI":"10.1016\/j.athoracsur.2017.02.034","article-title":"Impact of high-priority allocation on lung and heart-lung transplantation for pulmonary hypertension","volume":"104","author":"Savale","year":"2017","journal-title":"Ann Thorac Surg"},{"key":"2024112623020512000_64.4.2401193.22","doi-asserted-by":"publisher","DOI":"10.1183\/23120541.00521-2023"},{"key":"2024112623020512000_64.4.2401193.23","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1007\/s41030-018-0052-z","article-title":"Volume management in pulmonary arterial hypertension patients: an expert pulmonary hypertension clinician perspective","volume":"4","author":"Hansen","year":"2018","journal-title":"Pulm Ther"},{"key":"2024112623020512000_64.4.2401193.24","doi-asserted-by":"crossref","first-page":"3627","DOI":"10.1093\/eurheartj\/ehad195","article-title":"2023 focused update of the 2021 ESC guidelines for the diagnosis and treatment of acute and chronic heart failure","volume":"44","author":"McDonagh","year":"2023","journal-title":"Eur Heart J"},{"key":"2024112623020512000_64.4.2401193.25","doi-asserted-by":"crossref","first-page":"2728","DOI":"10.1002\/ehf2.13945","article-title":"Renal replacement therapy as a therapeutic option for right heart failure in severe pulmonary arterial hypertension","volume":"9","author":"Shimbo","year":"2022","journal-title":"ESC Heart Fail"},{"key":"2024112623020512000_64.4.2401193.26","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1159\/000339346","article-title":"Renal replacement therapy in patients with severe precapillary pulmonary hypertension with acute right heart failure","volume":"85","author":"Sztrymf","year":"2013","journal-title":"Respiration"},{"key":"2024112623020512000_64.4.2401193.27","first-page":"e28792","article-title":"Renal replacement therapy in patients with acute decompensated pulmonary hypertension admitted to the intensive care unit","volume":"14","author":"Garcia","year":"2022","journal-title":"Cureus"},{"key":"2024112623020512000_64.4.2401193.28","first-page":"230","article-title":"Predictors of survival in patients with pulmonary hypertension and acute right heart failure","volume":"121","author":"Ambroz","year":"2020","journal-title":"Bratisl Lek Listy"},{"key":"2024112623020512000_64.4.2401193.29","doi-asserted-by":"publisher","DOI":"10.1097\/01.CCM.0000242157.19347.50"},{"key":"2024112623020512000_64.4.2401193.30","doi-asserted-by":"publisher","DOI":"10.1055\/s-0040-1710320"},{"key":"2024112623020512000_64.4.2401193.31","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0907118"},{"key":"2024112623020512000_64.4.2401193.32","doi-asserted-by":"publisher","DOI":"10.1097\/01.CCM.0000120052.77953.07"},{"key":"2024112623020512000_64.4.2401193.33","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2044.2002.02324.x"},{"key":"2024112623020512000_64.4.2401193.34","doi-asserted-by":"publisher","DOI":"10.1136\/thoraxjnl-2016-209725"},{"key":"2024112623020512000_64.4.2401193.35","doi-asserted-by":"publisher","DOI":"10.1510\/icvts.2007.159624"},{"key":"2024112623020512000_64.4.2401193.36","doi-asserted-by":"publisher","DOI":"10.1186\/cc1069"},{"key":"2024112623020512000_64.4.2401193.37","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.00116313"},{"key":"2024112623020512000_64.4.2401193.38","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1111\/1756-185X.12409","article-title":"Severe pulmonary arterial hypertension secondary to lupus in the emergency department: proactive intense care associated with a better short-term survival","volume":"18","author":"Chen","year":"2015","journal-title":"Int J Rheum Dis"},{"key":"2024112623020512000_64.4.2401193.39","doi-asserted-by":"publisher","DOI":"10.1002\/art.23303"},{"key":"2024112623020512000_64.4.2401193.40","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1016\/j.healun.2022.02.022","article-title":"Central venoarterial extracorporeal membrane oxygenation as a bridge to recovery after pulmonary endarterectomy in patients with decompensated right heart failure","volume":"41","author":"Abdelnour-Berchtold","year":"2022","journal-title":"J Heart Lung Transplant"},{"key":"2024112623020512000_64.4.2401193.41","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.ijcard.2016.07.021","article-title":"Rescue balloon pulmonary angioplasty for early failure of pulmonary endarterectomy: the earlier the better?","volume":"222","author":"Collaud","year":"2016","journal-title":"Int J Cardiol"},{"key":"2024112623020512000_64.4.2401193.42","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1186\/s13613-024-01242-0","article-title":"The value of right ventricular to pulmonary arterial coupling in the critically ill: a National Echocardiography Database of Australia (NEDA) substudy","volume":"14","author":"Bowcock","year":"2024","journal-title":"Ann Intensive Care"},{"key":"2024112623020512000_64.4.2401193.43","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201010-1584CI"},{"key":"2024112623020512000_64.4.2401193.44","doi-asserted-by":"crossref","first-page":"1498","DOI":"10.1007\/s00134-022-06835-6","article-title":"Central venous pressure (CVP)","volume":"48","author":"Hamzaoui","year":"2022","journal-title":"Intensive Care Med"},{"key":"2024112623020512000_64.4.2401193.45","doi-asserted-by":"publisher","DOI":"10.1378\/chest.07-0694"},{"key":"2024112623020512000_64.4.2401193.46","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa021108"},{"key":"2024112623020512000_64.4.2401193.47","doi-asserted-by":"crossref","first-page":"20458940211037529","DOI":"10.1177\/20458940211037529","article-title":"Serious illness conversations in pulmonary hypertension","volume":"11","author":"Ismail","year":"2021","journal-title":"Pulm Circ"},{"key":"2024112623020512000_64.4.2401193.48","doi-asserted-by":"crossref","first-page":"10742484211069005","DOI":"10.1177\/10742484211069005","article-title":"A review of pulmonary arterial hypertension treatment in extracorporeal membrane oxygenation: a case series of adult patients","volume":"27","author":"Torbic","year":"2022","journal-title":"J Cardiovasc Pharmacol Ther"},{"key":"2024112623020512000_64.4.2401193.49","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201104-0662CI"},{"key":"2024112623020512000_64.4.2401193.50","doi-asserted-by":"publisher","DOI":"10.1378\/chest.12-1141"},{"key":"2024112623020512000_64.4.2401193.51","doi-asserted-by":"crossref","first-page":"192","DOI":"10.3390\/jcm13010192","article-title":"Intraoperative extracorporeal support during lung transplantation: not just for the high-risk patient","volume":"13","author":"Laskey","year":"2023","journal-title":"J Clin Med"},{"key":"2024112623020512000_64.4.2401193.52","doi-asserted-by":"crossref","first-page":"e427","DOI":"10.1016\/j.athoracsur.2022.02.036","article-title":"Bridge to transplant: central extracorporeal membrane oxygenation with pulmonary artery drainage","volume":"114","author":"Patel","year":"2022","journal-title":"Ann Thorac Surg"},{"key":"2024112623020512000_64.4.2401193.53","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/j.xjtc.2023.01.015","article-title":"Unique extracorporeal membrane oxygenator configuration for isolated right ventricular failure","volume":"18","author":"DeBose-Scarlett","year":"2023","journal-title":"JTCVS Tech"},{"key":"2024112623020512000_64.4.2401193.54","doi-asserted-by":"crossref","first-page":"1166","DOI":"10.1016\/j.athoracsur.2015.03.127","article-title":"Venovenous extracorporeal membrane oxygenation with atrial septostomy as a bridge to lung transplantation","volume":"101","author":"Kon","year":"2016","journal-title":"Ann Thorac Surg"},{"key":"2024112623020512000_64.4.2401193.55","doi-asserted-by":"crossref","first-page":"1000084","DOI":"10.3389\/fmed.2022.1000084","article-title":"Outcomes of patients with acute respiratory failure on veno-venous extracorporeal membrane oxygenation requiring additional circulatory support by veno-venoarterial extracorporeal membrane oxygenation","volume":"9","author":"Erlebach","year":"2022","journal-title":"Front Med"},{"key":"2024112623020512000_64.4.2401193.56","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2014.09.061"},{"key":"2024112623020512000_64.4.2401193.57","doi-asserted-by":"publisher","DOI":"10.1016\/j.healun.2011.03.002"},{"key":"2024112623020512000_64.4.2401193.58","first-page":"179","article-title":"Lung transplantation in Germany since the introduction of the Lung Allocation Score","volume":"114","author":"Gottlieb","year":"2017","journal-title":"Dtsch Arztebl Int"},{"key":"2024112623020512000_64.4.2401193.59","doi-asserted-by":"publisher","DOI":"10.1093\/icvts\/ivw075"},{"key":"2024112623020512000_64.4.2401193.60","doi-asserted-by":"crossref","first-page":"1831.e7","DOI":"10.1016\/j.cjca.2020.06.001","article-title":"Pumpless lung assist as a bridge to medical therapy in a teenager with pulmonary arterial hypertension and partial anomalous pulmonary venous return","volume":"36","author":"Hascoet","year":"2020","journal-title":"Can J Cardiol"},{"key":"2024112623020512000_64.4.2401193.61","doi-asserted-by":"crossref","first-page":"1283065","DOI":"10.3389\/fmed.2024.1283065","article-title":"Case report: extracorporeal life support as a successful bridge to recovery in an incident case of pulmonary arterial hypertension","volume":"11","author":"Pequignot","year":"2024","journal-title":"Front Med"},{"key":"2024112623020512000_64.4.2401193.62","doi-asserted-by":"crossref","first-page":"2193","DOI":"10.1016\/j.jtcvs.2017.10.144","article-title":"Intraoperative extracorporeal membrane oxygenation and the possibility of postoperative prolongation improve survival in bilateral lung transplantation","volume":"155","author":"Hoetzenecker","year":"2018","journal-title":"J Thorac Cardiovasc Surg"},{"key":"2024112623020512000_64.4.2401193.63","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1093\/ejcts\/ezx212","article-title":"Lung transplantation for idiopathic pulmonary arterial hypertension on intraoperative and postoperatively prolonged extracorporeal membrane oxygenation provides optimally controlled reperfusion and excellent outcome","volume":"53","author":"Moser","year":"2018","journal-title":"Eur J Cardiothorac Surg"},{"key":"2024112623020512000_64.4.2401193.64","doi-asserted-by":"publisher","DOI":"10.1016\/j.chest.2019.03.003"},{"key":"2024112623020512000_64.4.2401193.65","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.01345-2024"},{"key":"2024112623020512000_64.4.2401193.66","doi-asserted-by":"crossref","first-page":"468","DOI":"10.1016\/j.jacc.2021.05.039","article-title":"Pulmonary-to-systemic arterial shunt to treat children with severe pulmonary hypertension","volume":"78","author":"Grady","year":"2021","journal-title":"J Am Coll Cardiol"},{"key":"2024112623020512000_64.4.2401193.67","doi-asserted-by":"crossref","first-page":"1028304","DOI":"10.3389\/fcvm.2022.1028304","article-title":"Long-term outcomes of transcatheter Potts shunt in children with suprasystemic pulmonary arterial hypertension","volume":"9","author":"Haddad","year":"2022","journal-title":"Front Cardiovasc Med"},{"key":"2024112623020512000_64.4.2401193.68","doi-asserted-by":"crossref","first-page":"943","DOI":"10.1016\/j.jtcvs.2023.11.045","article-title":"Thirty years of surgical management of pediatric pulmonary hypertension: mid-term outcomes following reverse Potts shunt and transplantation","volume":"168","author":"Valdeolmillos","year":"2024","journal-title":"J Thorac Cardiovasc Surg"},{"key":"2024112623020512000_64.4.2401193.69","doi-asserted-by":"crossref","first-page":"856","DOI":"10.1016\/j.athoracsur.2018.04.060","article-title":"Single- versus double-lung transplantation in pulmonary fibrosis: impact of age and pulmonary hypertension","volume":"106","author":"Villavicencio","year":"2018","journal-title":"Ann Thorac Surg"},{"key":"2024112623020512000_64.4.2401193.70","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1111\/tri.13409","article-title":"Double-lung versus heart-lung transplantation for precapillary pulmonary arterial hypertension: a 24-year single-center retrospective study","volume":"32","author":"Brouckaert","year":"2019","journal-title":"Transpl Int"},{"key":"2024112623020512000_64.4.2401193.71","doi-asserted-by":"crossref","first-page":"2097","DOI":"10.1016\/j.chest.2020.05.597","article-title":"Not all septal defects are equal: outcomes of bilateral lung transplant with cardiac defect repair vs combined heart-lung transplant in patients with Eisenmenger syndrome in the United States","volume":"158","author":"Sertic","year":"2020","journal-title":"Chest"},{"key":"2024112623020512000_64.4.2401193.72","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.02388-2021"},{"key":"2024112623020512000_64.4.2401193.73","doi-asserted-by":"crossref","first-page":"2543","DOI":"10.1016\/j.jtcvs.2019.09.178","article-title":"Lung transplantation for pulmonary hypertension with giant pulmonary artery aneurysm","volume":"159","author":"Schwarz","year":"2020","journal-title":"J Thorac Cardiovasc Surg"},{"key":"2024112623020512000_64.4.2401193.74","doi-asserted-by":"crossref","first-page":"1392","DOI":"10.1164\/rccm.201508-1522OC","article-title":"Diastolic dysfunction increases the risk of primary graft dysfunction after lung transplant","volume":"193","author":"Porteous","year":"2016","journal-title":"Am J Respir Crit Care Med"},{"key":"2024112623020512000_64.4.2401193.75","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2014.04.031"},{"key":"2024112623020512000_64.4.2401193.76","doi-asserted-by":"crossref","first-page":"2705","DOI":"10.1111\/ajt.14352","article-title":"Impact of left ventricular diastolic dysfunction on lung transplantation outcome in patients with pulmonary arterial hypertension","volume":"17","author":"Avriel","year":"2017","journal-title":"Am J Transplant"},{"key":"2024112623020512000_64.4.2401193.77","doi-asserted-by":"publisher","DOI":"10.1016\/j.healun.2019.08.001"},{"key":"2024112623020512000_64.4.2401193.78","doi-asserted-by":"crossref","first-page":"568","DOI":"10.1513\/AnnalsATS.201512-823LE","article-title":"Variability in lung transplant education during pulmonary and critical care medicine fellowship: results of a national survey","volume":"13","author":"Town","year":"2016","journal-title":"Ann Am Thorac Soc"},{"key":"2024112623020512000_64.4.2401193.79","doi-asserted-by":"publisher","DOI":"10.1016\/j.healun.2021.07.005"},{"key":"2024112623020512000_64.4.2401193.80","doi-asserted-by":"crossref","first-page":"2200879","DOI":"10.1183\/13993003.00879-2022","article-title":"2022 ESC\/ERS guidelines for the diagnosis and treatment of pulmonary hypertension","volume":"61","author":"Humbert","year":"2022","journal-title":"Eur Respir J"},{"key":"2024112623020512000_64.4.2401193.81","doi-asserted-by":"crossref","first-page":"820","DOI":"10.1016\/S2213-2600(23)00259-X","article-title":"Pulmonary hypertension associated with lung disease: new insights into pathomechanisms, diagnosis, and management","volume":"11","author":"Olsson","year":"2023","journal-title":"Lancet Respir Med"},{"key":"2024112623020512000_64.4.2401193.82","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.00465-2017"},{"key":"2024112623020512000_64.4.2401193.83","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.01747-2019"},{"key":"2024112623020512000_64.4.2401193.84","doi-asserted-by":"crossref","first-page":"2045894020194851","DOI":"10.1177\/2045894020914851","article-title":"Idiopathic pulmonary arterial hypertension and co-existing lung disease: is this a new phenotype?","volume":"10","author":"Peacock","year":"2020","journal-title":"Pulm Circ"},{"key":"2024112623020512000_64.4.2401193.85","doi-asserted-by":"publisher","DOI":"10.1016\/S2213-2600(22)00097-2"},{"key":"2024112623020512000_64.4.2401193.86","doi-asserted-by":"crossref","first-page":"1496","DOI":"10.1164\/rccm.201712-2405LE","article-title":"Disproportionate right ventricular dysfunction and poor survival in group 3 pulmonary hypertension","volume":"197","author":"Prins","year":"2018","journal-title":"Am J Respir Crit Care Med"},{"key":"2024112623020512000_64.4.2401193.87","doi-asserted-by":"crossref","first-page":"e7","DOI":"10.1164\/rccm.202206-1041ST","article-title":"Syndrome of combined pulmonary fibrosis and emphysema: an official ATS\/ERS\/JRS\/ALAT research statement","volume":"206","author":"Cottin","year":"2022","journal-title":"Am J Respir Crit Care Med"},{"key":"2024112623020512000_64.4.2401193.88","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.00038709"},{"key":"2024112623020512000_64.4.2401193.89","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCHEARTFAILURE.112.000008"},{"key":"2024112623020512000_64.4.2401193.90","doi-asserted-by":"publisher","DOI":"10.1002\/art.30423"},{"key":"2024112623020512000_64.4.2401193.91","doi-asserted-by":"crossref","first-page":"e0197112","DOI":"10.1371\/journal.pone.0197112","article-title":"Clinical phenotypes and survival of pre-capillary pulmonary hypertension in systemic sclerosis","volume":"13","author":"Launay","year":"2018","journal-title":"PLoS One"},{"key":"2024112623020512000_64.4.2401193.92","doi-asserted-by":"publisher","DOI":"10.1016\/j.lpm.2014.01.020"},{"key":"2024112623020512000_64.4.2401193.93","doi-asserted-by":"crossref","first-page":"903","DOI":"10.1016\/j.healun.2018.03.003","article-title":"Lung transplantation for scleroderma lung disease: an international, multicenter, observational cohort study","volume":"37","author":"Prad\u00e8re","year":"2018","journal-title":"J Heart Lung Transplant"},{"key":"2024112623020512000_64.4.2401193.94","doi-asserted-by":"crossref","first-page":"1251","DOI":"10.1016\/j.healun.2021.07.014","article-title":"ISHLT consensus document on lung transplantation in patients with connective tissue disease: part I: epidemiology, assessment of extrapulmonary conditions, candidate evaluation, selection criteria, and pathology statements","volume":"40","author":"Crespo","year":"2021","journal-title":"J Heart Lung Transplant"},{"key":"2024112623020512000_64.4.2401193.95","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.116.023033"},{"key":"2024112623020512000_64.4.2401193.96","doi-asserted-by":"crossref","first-page":"3388","DOI":"10.1111\/ajt.16600","article-title":"Transplantation for pulmonary arterial hypertension with congenital heart disease: impact on outcomes of the current therapeutic approach including a high-priority allocation program","volume":"21","author":"Hasco\u00ebt","year":"2021","journal-title":"Am J Transplant"},{"key":"2024112623020512000_64.4.2401193.97","doi-asserted-by":"publisher","DOI":"10.1136\/heartjnl-2019-315345"},{"key":"2024112623020512000_64.4.2401193.98","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1164\/rccm.202201-0217OC","article-title":"The lung allocation score remains inequitable for patients with pulmonary arterial hypertension, even after the 2015 revision","volume":"207","author":"Kolaitis","year":"2023","journal-title":"Am J Respir Crit Care Med"},{"key":"2024112623020512000_64.4.2401193.99","doi-asserted-by":"crossref","first-page":"1641","DOI":"10.1016\/j.healun.2021.08.005","article-title":"Lung transplantation disparities based on diagnosis for patients bridging to transplant on extracorporeal membrane oxygenation","volume":"40","author":"Furfaro","year":"2021","journal-title":"J Heart Lung Transplant"},{"key":"2024112623020512000_64.4.2401193.100","doi-asserted-by":"crossref","first-page":"992","DOI":"10.1016\/j.chest.2023.04.047","article-title":"Lung transplantation for pulmonary arterial hypertension","volume":"164","author":"Kolaitis","year":"2023","journal-title":"Chest"},{"key":"2024112623020512000_64.4.2401193.101","unstructured":"OPTN Lung Transplantation Committee . Public Comment Proposal Revise Lung Review Board Guidelines, Guidance, and Policy for Continuous Distribution. 2022. https:\/\/optn.transplant.hrsa.gov\/media\/hzdktvbm\/revise-lung-review-board-guidelines-guidance-and-policy-for-continuous-distribution_lung_pc-summer-2022.pdf."},{"key":"2024112623020512000_64.4.2401193.102","doi-asserted-by":"crossref","first-page":"911","DOI":"10.1016\/j.athoracsur.2021.03.092","article-title":"The impact of center volume on outcomes in lung transplantation","volume":"113","author":"Yang","year":"2022","journal-title":"Ann Thorac Surg"},{"key":"2024112623020512000_64.4.2401193.103","doi-asserted-by":"crossref","first-page":"1327","DOI":"10.1016\/j.healun.2021.07.012","article-title":"International consensus recommendations for anesthetic and intensive care management of lung transplantation. An EACTAIC, SCA, ISHLT, ESOT, ESTS, and AST approved document","volume":"40","author":"Marczin","year":"2021","journal-title":"J Heart Lung Transplant"},{"key":"2024112623020512000_64.4.2401193.104","doi-asserted-by":"publisher","DOI":"10.1378\/chest.111.5.1229"},{"key":"2024112623020512000_64.4.2401193.105","doi-asserted-by":"crossref","first-page":"1351","DOI":"10.1016\/j.jtcvs.2021.10.076","article-title":"Effect of mode of intraoperative support on primary graft dysfunction after lung transplant","volume":"164","author":"Loor","year":"2022","journal-title":"J Thorac Cardiovasc Surg"},{"key":"2024112623020512000_64.4.2401193.106","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1097\/MOT.0000000000000873","article-title":"Procedural mechanical support for lung transplantation","volume":"26","author":"Schwarz","year":"2021","journal-title":"Curr Opin Organ Transplant"},{"key":"2024112623020512000_64.4.2401193.107","doi-asserted-by":"publisher","DOI":"10.1016\/S0003-4975(96)00931-9"},{"key":"2024112623020512000_64.4.2401193.108","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201210-1865OC"},{"key":"2024112623020512000_64.4.2401193.109","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1093\/ejcts\/ezy089","article-title":"Central versus peripheral cannulation of extracorporeal membrane oxygenation support during double lung transplant for pulmonary hypertension","volume":"54","author":"Glorion","year":"2018","journal-title":"Eur J Cardiothorac Surg"},{"key":"2024112623020512000_64.4.2401193.110","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2010.08.648"},{"key":"2024112623020512000_64.4.2401193.111","doi-asserted-by":"publisher","DOI":"10.1016\/S1010-7940(02)00058-1"},{"key":"2024112623020512000_64.4.2401193.112","doi-asserted-by":"publisher","DOI":"10.1097\/TP.0000000000000348"},{"key":"2024112623020512000_64.4.2401193.113","doi-asserted-by":"crossref","first-page":"1514","DOI":"10.1513\/AnnalsATS.201610-810OC","article-title":"Clinical risk factors and prognostic model for primary graft dysfunction after lung transplantation in patients with pulmonary hypertension","volume":"14","author":"Porteous","year":"2017","journal-title":"Ann Am Thorac Soc"},{"key":"2024112623020512000_64.4.2401193.114","doi-asserted-by":"publisher","DOI":"10.1111\/j.1751-7133.2008.00037.x"},{"key":"2024112623020512000_64.4.2401193.115","first-page":"F486","article-title":"Renin release from isolated juxtaglomerular apparatus depends on macula densa chloride transport","volume":"260","author":"Lorenz","year":"1991","journal-title":"Am J Physiol"},{"key":"2024112623020512000_64.4.2401193.116","doi-asserted-by":"crossref","first-page":"524","DOI":"10.1016\/j.jtcvs.2021.05.034","article-title":"Early implementation of renal replacement therapy after lung transplantation does not impair long-term kidney function in patients with idiopathic pulmonary arterial hypertension","volume":"163","author":"Benazzo","year":"2022","journal-title":"J Thorac Cardiovasc Surg"},{"key":"2024112623020512000_64.4.2401193.117","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1016\/j.jvc.2018.07.007","article-title":"Right ventricular outflow tract fractional shortening: an echocardiographic index of right ventricular systolic function in dogs with pulmonary hypertension","volume":"20","author":"Caivano","year":"2018","journal-title":"J Vet Cardiol"},{"key":"2024112623020512000_64.4.2401193.118","doi-asserted-by":"publisher","DOI":"10.1378\/chest.14-2188"},{"key":"2024112623020512000_64.4.2401193.119","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1016\/j.athoracsur.2016.11.056","article-title":"Awake extracorporeal membrane oxygenation as bridge to lung transplantation: a 9-year experience","volume":"104","author":"Biscotti","year":"2017","journal-title":"Ann Thorac Surg"},{"key":"2024112623020512000_64.4.2401193.120","doi-asserted-by":"publisher","DOI":"10.4187\/respcare.02155"},{"key":"2024112623020512000_64.4.2401193.121","doi-asserted-by":"crossref","first-page":"999","DOI":"10.1097\/TP.0000000000003481","article-title":"Month-long respiratory support by a wearable pumping artificial lung in an ovine model","volume":"105","author":"Orizondo","year":"2021","journal-title":"Transplantation"},{"key":"2024112623020512000_64.4.2401193.122","doi-asserted-by":"crossref","first-page":"806","DOI":"10.1016\/j.healun.2017.02.025","article-title":"In vitro and in vivo evaluation of a novel integrated wearable artificial lung","volume":"36","author":"Madhani","year":"2017","journal-title":"J Heart Lung Transplant"},{"key":"2024112623020512000_64.4.2401193.123","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1097\/MAT.0000000000000740","article-title":"In vivo 5 day animal studies of a compact, wearable pumping artificial lung","volume":"65","author":"Madhani","year":"2019","journal-title":"ASAIO J"},{"key":"2024112623020512000_64.4.2401193.124","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1016\/j.healun.2023.10.017","article-title":"Ambulatory 7-day mechanical circulatory support in sheep model of pulmonary hypertension and right heart failure","volume":"43","author":"Ukita","year":"2024","journal-title":"J Heart Lung Transplant"},{"key":"2024112623020512000_64.4.2401193.125","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1014597"},{"key":"2024112623020512000_64.4.2401193.126","doi-asserted-by":"crossref","first-page":"4810","DOI":"10.1038\/s41467-023-40468-7","article-title":"A machine-learning approach to human ex vivo lung perfusion predicts transplantation outcomes and promotes organ utilization","volume":"14","author":"Sage","year":"2023","journal-title":"Nat Commun"},{"key":"2024112623020512000_64.4.2401193.127","doi-asserted-by":"publisher","DOI":"10.1016\/j.healun.2014.11.009"},{"key":"2024112623020512000_64.4.2401193.128","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/j.ccm.2022.10.006","article-title":"Expanding the lung donor pool: donation after circulatory death, ex-vivo lung perfusion and hepatitis C donors","volume":"44","author":"Saddoughi","year":"2023","journal-title":"Clin Chest Med"},{"key":"2024112623020512000_64.4.2401193.129","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1016\/S2213-2600(19)30268-1","article-title":"Prevention of viral transmission during lung transplantation with hepatitis C-viraemic donors: an open-label, single-centre, pilot trial","volume":"8","author":"Cypel","year":"2020","journal-title":"Lancet Respir Med"},{"key":"2024112623020512000_64.4.2401193.130","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1038\/s41467-018-08261-z","article-title":"Inactivating hepatitis C virus in donor lungs using light therapies during normothermic ex vivo lung perfusion","volume":"10","author":"Galasso","year":"2019","journal-title":"Nat Commun"},{"key":"2024112623020512000_64.4.2401193.131","doi-asserted-by":"crossref","first-page":"eabf7601","DOI":"10.1126\/scitranslmed.abf7601","article-title":"Static lung storage at 10\u00b0C maintains mitochondrial health and preserves donor organ function","volume":"13","author":"Ali","year":"2021","journal-title":"Sci Transl Med"},{"key":"2024112623020512000_64.4.2401193.132","doi-asserted-by":"crossref","first-page":"488","DOI":"10.1016\/j.jtcvs.2016.08.067","article-title":"CRISPR genome-editing: a medical revolution","volume":"153","author":"Butler","year":"2017","journal-title":"J Thorac Cardiovasc Surg"},{"key":"2024112623020512000_64.4.2401193.133","doi-asserted-by":"publisher","DOI":"10.1111\/xen.12019"},{"key":"2024112623020512000_64.4.2401193.134","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1016\/j.ijsu.2015.08.038","article-title":"Current status of pig heart xenotransplantation","volume":"23","author":"Mohiuddin","year":"2015","journal-title":"Int J Surg"},{"key":"2024112623020512000_64.4.2401193.135","doi-asserted-by":"crossref","first-page":"11138","DOI":"10.1038\/ncomms11138","article-title":"Chimeric 2C10R4 anti-CD40 antibody therapy is critical for long-term survival of GTKO.hCD46.hTBM pig-to-primate cardiac xenograft","volume":"7","author":"Mohiuddin","year":"2016","journal-title":"Nat Commun"}],"container-title":["European Respiratory Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1183\/13993003.01193-2024","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,24]],"date-time":"2025-02-24T07:22:25Z","timestamp":1740381745000},"score":1,"resource":{"primary":{"URL":"https:\/\/publications.ersnet.org\/lookup\/doi\/10.1183\/13993003.01193-2024"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,8,29]]},"references-count":135,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2024,10,31]]},"published-print":{"date-parts":[[2024,10]]}},"alternative-id":["10.1183\/13993003.01193-2024"],"URL":"https:\/\/doi.org\/10.1183\/13993003.01193-2024","relation":{},"ISSN":["0903-1936","1399-3003"],"issn-type":[{"value":"0903-1936","type":"print"},{"value":"1399-3003","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,8,29]]}}}