{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T06:36:41Z","timestamp":1789540601657,"version":"build-2803163510"},"reference-count":29,"publisher":"European Respiratory Society (ERS)","issue":"1","funder":[{"DOI":"10.13039\/501100001921","name":"Public Health Research Programme","doi-asserted-by":"publisher","award":["10064"],"award-info":[{"award-number":["10064"]}],"id":[{"id":"10.13039\/501100001921","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Bart's charity","award":["421\/2301"],"award-info":[{"award-number":["421\/2301"]}]}],"content-domain":{"domain":["publications.ersnet.org"],"crossmark-restriction":true},"short-container-title":["Eur Respir J"],"accepted":{"date-parts":[[2017,10,6]]},"published-print":{"date-parts":[[2018,1]]},"abstract":"<jats:p>Latent tuberculosis infection (LTBI) screening is an important intervention for tuberculosis (TB) elimination in low-incidence countries and is, therefore, a key component of England's TB control strategy. This study describes outcomes from a LTBI screening programme in a high-incidence area to inform national LTBI screening in England and other low-incidence countries.<\/jats:p><jats:p>We conducted a retrospective cohort study of LTBI screening among eligible migrants (from high-incidence countries and entered the UK within the last 5\u2005years), who were identified at primary-care clinics in Newham, London between August 2014 and August 2015. Multivariable logistic regression was used to identify factors associated with LTBI testing uptake, interferon-\u03b3 release assay (IGRA) positivity and treatment uptake.<\/jats:p><jats:p>40% of individuals offered LTBI screening received an IGRA test. The majority of individuals tested were 16\u201335\u2005years old, male and born in India, Bangladesh or Pakistan. Country of birth, smoking status and co-morbidities were associated with LTBI testing uptake. IGRA positivity was 32% among those tested and was significantly associated with country of birth, age, sex and co-morbidities.<\/jats:p><jats:p>This study identifies factors associated with screening uptake, IGRA positivity and treatment uptake, and improves understanding of groups that should be supported to increase acceptability of LTBI testing and treatment in the community.<\/jats:p>","DOI":"10.1183\/13993003.01226-2017","type":"journal-article","created":{"date-parts":[[2018,1,12]],"date-time":"2018-01-12T01:11:18Z","timestamp":1515719478000},"page":"1701226","update-policy":"https:\/\/doi.org\/10.1183\/ers-crossmark-policy","source":"Crossref","is-referenced-by-count":27,"title":["National roll-out of latent tuberculosis testing and treatment for new migrants in England: a retrospective evaluation in a high-incidence area"],"prefix":"10.1183","volume":"51","author":[{"given":"Miranda G.","family":"Loutet","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew","family":"Burman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nivenka","family":"Jayasekera","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Duncan","family":"Trathen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susan","family":"Dart","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heinke","family":"Kunst","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dominik","family":"Zenner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"81","published-online":{"date-parts":[[2018,1,11]]},"reference":[{"key":"2024101909235598000_51.1.1701226.1","unstructured":"WHO Global TB Programme. 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Collaborative TB Strategy for England 2015-2020. Available from www.gov.uk\/government\/uploads\/system\/uploads\/attachment_data\/file\/403231\/Collaborative_TB_Strategy_for_England_2015_2020_.pdf Date last accessed: July 15 2017; date last updated: January 2015."},{"key":"2024101909235598000_51.1.1701226.12","unstructured":"Office for National Statistics. Population of the UK by Country of Birth and Nationality: 2015. Office for National Statistics. Available from www.ons.gov.uk\/peoplepopulationandcommunity\/populationandmigration\/internationalmigration\/datasets\/populationoftheunitedkingdombycountryofbirthandnationality Date last accessed: July 15 2017."},{"key":"2024101909235598000_51.1.1701226.13","unstructured":"Public Health England. Tuberculosis in London: Annual review (2014 data). Public Health England. 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