{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,6]],"date-time":"2026-07-06T10:48:05Z","timestamp":1783334885900,"version":"3.54.6"},"reference-count":15,"publisher":"European Respiratory Society (ERS)","issue":"3","license":[{"start":{"date-parts":[[2019,12,5]],"date-time":"2019-12-05T00:00:00Z","timestamp":1575504000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.ersjournals.com\/user-licence"}],"funder":[{"DOI":"10.13039\/100011102","name":"Seventh Framework Programme","doi-asserted-by":"publisher","award":["270194"],"award-info":[{"award-number":["270194"]}],"id":[{"id":"10.13039\/100011102","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003130","name":"Fonds Wetenschappelijk Onderzoek","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003130","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009010","name":"Novartis Pharmaceuticals UK Limited","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100009010","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["publications.ersnet.org"],"crossmark-restriction":true},"short-container-title":["Eur Respir J"],"accepted":{"date-parts":[[2019,11,12]]},"published-print":{"date-parts":[[2020,3]]},"DOI":"10.1183\/13993003.01345-2019","type":"journal-article","created":{"date-parts":[[2019,12,5]],"date-time":"2019-12-05T13:25:25Z","timestamp":1575552325000},"page":"1901345","update-policy":"https:\/\/doi.org\/10.1183\/ers-crossmark-policy","source":"Crossref","is-referenced-by-count":16,"title":["Increased ventilation heterogeneity in asthma can be attributed to proximal bronchioles"],"prefix":"10.1183","volume":"55","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0127-7311","authenticated-orcid":false,"given":"Brody","family":"Foy","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Kay","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Salman","family":"Siddiqui","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chris","family":"Brightling","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manuel","family":"Paiva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sylvia","family":"Verbanck","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"81","published-online":{"date-parts":[[2019,12,5]]},"reference":[{"key":"2024102101165861000_55.3.1901345.1","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.00069712"},{"key":"2024102101165861000_55.3.1901345.2","doi-asserted-by":"crossref","first-page":"809","DOI":"10.1002\/cphy.c100018","article-title":"Gas mixing in the airways and airspaces","volume":"1","author":"Verbanck","year":"2011","journal-title":"Compreh Physiol"},{"key":"2024102101165861000_55.3.1901345.3","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1016\/j.resp.2018.09.010","article-title":"A simulation study of diffusion-convection interaction and its effect on multiple breath washout indices","volume":"258","author":"Verbanck","year":"2018","journal-title":"Respir Physiol Neurobiol"},{"key":"2024102101165861000_55.3.1901345.4","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2011.11.017"},{"key":"2024102101165861000_55.3.1901345.5","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1016\/S2213-2600(19)30049-9","article-title":"Exploring the relevance and extent of small airways dysfunction in asthma (ATLANTIS): baseline data from a prospective cohort study","volume":"7","author":"Postma","year":"2019","journal-title":"Lancet Respir Med"},{"key":"2024102101165861000_55.3.1901345.6","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1016\/j.jaci.2015.06.027","article-title":"Characterization of acinar airspace involvement in asthmatic patients by using inert gas washout and hyperpolarized 3helium magnetic resonance","volume":"137","author":"Gonem","year":"2016","journal-title":"J Allergy Clin Immunol"},{"key":"2024102101165861000_55.3.1901345.7","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2009.10.053"},{"key":"2024102101165861000_55.3.1901345.8","doi-asserted-by":"publisher","DOI":"10.1136\/thx.2006.069682"},{"key":"2024102101165861000_55.3.1901345.9","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.00393-2016"},{"key":"2024102101165861000_55.3.1901345.10","doi-asserted-by":"publisher","DOI":"10.1152\/japplphysiol.00640.2016"},{"key":"2024102101165861000_55.3.1901345.11","doi-asserted-by":"publisher","DOI":"10.1152\/japplphysiol.01049.2015"},{"key":"2024102101165861000_55.3.1901345.12","first-page":"e13709","article-title":"Modelling the effect of gravity on inert-gas washout outputs","volume":"6","author":"Foy","year":"2018","journal-title":"Phys Rep"},{"key":"2024102101165861000_55.3.1901345.13","doi-asserted-by":"crossref","first-page":"e0144105","DOI":"10.1371\/journal.pone.0144105","article-title":"Development and analysis of patient-based complete conducting airway models","volume":"10","author":"Bordas","year":"2015","journal-title":"PLoS One"},{"key":"2024102101165861000_55.3.1901345.14","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1165\/rcmb.2018-0011OC","article-title":"Unraveling a clinical paradox: why does bronchial thermoplasty work in asthma?","volume":"59","author":"Donovan","year":"2018","journal-title":"Am J Respir Cell Mol Biol"},{"key":"2024102101165861000_55.3.1901345.15","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1016\/j.jcp.2019.03.014","article-title":"A computationally tractable scheme for simulation of the human pulmonary system","volume":"388","author":"Foy","year":"2019","journal-title":"J Comput Phys"}],"container-title":["European Respiratory Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1183\/13993003.01345-2019","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,24]],"date-time":"2025-02-24T08:12:32Z","timestamp":1740384752000},"score":1,"resource":{"primary":{"URL":"https:\/\/publications.ersnet.org\/lookup\/doi\/10.1183\/13993003.01345-2019"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,12,5]]},"references-count":15,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2020,3,12]]},"published-print":{"date-parts":[[2020,3]]}},"alternative-id":["10.1183\/13993003.01345-2019"],"URL":"https:\/\/doi.org\/10.1183\/13993003.01345-2019","relation":{},"ISSN":["0903-1936","1399-3003"],"issn-type":[{"value":"0903-1936","type":"print"},{"value":"1399-3003","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,12,5]]}}}