{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T07:21:28Z","timestamp":1788420088909,"version":"build-2803163510"},"reference-count":33,"publisher":"European Respiratory Society (ERS)","issue":"1","license":[{"start":{"date-parts":[[2025,2,27]],"date-time":"2025-02-27T00:00:00Z","timestamp":1740614400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"Diputaci\u00f3 de Lleida","award":["PIRS22\/01"],"award-info":[{"award-number":["PIRS22\/01"]}]},{"DOI":"10.13039\/501100004587","name":"Instituto de Salud Carlos III","doi-asserted-by":"publisher","award":["CP23\/00095"],"award-info":[{"award-number":["CP23\/00095"]}],"id":[{"id":"10.13039\/501100004587","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004587","name":"Instituto de Salud Carlos III","doi-asserted-by":"publisher","award":["FI23\/00253"],"award-info":[{"award-number":["FI23\/00253"]}],"id":[{"id":"10.13039\/501100004587","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004587","name":"Instituto de Salud Carlos III","doi-asserted-by":"publisher","award":["PI22\/00636"],"award-info":[{"award-number":["PI22\/00636"]}],"id":[{"id":"10.13039\/501100004587","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007509","name":"Sociedad Espa\u00f1ola de Neumolog\u00eda y Cirug\u00eda Tor\u00e1cica","doi-asserted-by":"publisher","award":["2018\/662"],"award-info":[{"award-number":["2018\/662"]}],"id":[{"id":"10.13039\/501100007509","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["publications.ersnet.org"],"crossmark-restriction":true},"short-container-title":["Eur Respir J"],"accepted":{"date-parts":[[2025,1,31]]},"published-print":{"date-parts":[[2025,7]]},"abstract":"<jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>The effects of continuous positive airway pressure (CPAP) on blood pressure (BP) in normotensive subjects, particularly among those with a dipping BP pattern, remain uncertain, raising questions about its indication for this group of patients. We assessed the impact of CPAP on BP in normotensive subjects with a dipping BP pattern and severe obstructive sleep apnoea (OSA).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>This was a randomised, parallel, prospective, controlled trial. Inclusion criteria were: age \u226518\u2005years, apnoea\u2013hypopnoea index \u226530\u2005events\u00b7h<jats:sup>\u22121<\/jats:sup>, mean 24-h BP &lt;130\/80\u2005mmHg and daytime to night-time BP reduction \u226510%. Patients were randomly assigned to receive either CPAP treatment or usual care for 12\u2005weeks. The primary outcome was the change in ambulatory BP monitoring (ABPM) parameters from baseline to the 3-month follow-up.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>The 60 patients who completed the follow-up had a mean\u00b1<jats:sc>sd<\/jats:sc> age of 52.2\u00b110.8\u2005years and 40 (66.7%) were male. The intention-to-treat analysis showed no significant changes with CPAP, whereas the usual care group experienced increases in ABPM parameters. This resulted in a mean difference of \u22123.4\u2005mmHg (95% CI \u22126.124\u2013\u2009\u22120.676; p=0.015) in night-time diastolic BP between the groups. The per-protocol analysis indicated significant differences between the CPAP and usual care groups for all primary end-points, except for daytime systolic BP. For night-time systolic BP, the mean difference was \u22126.052\u2005mmHg (95% CI \u221210.895\u2013\u2009\u22121.208; p=0.016).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>These findings suggest a protective effect of CPAP, highlighting the importance of CPAP prescription for this population to control potential increases in BP and possibly prevent the onset of hypertension.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1183\/13993003.01954-2024","type":"journal-article","created":{"date-parts":[[2025,2,27]],"date-time":"2025-02-27T11:10:20Z","timestamp":1740654620000},"page":"2401954","update-policy":"https:\/\/doi.org\/10.1183\/ers-crossmark-policy","source":"Crossref","is-referenced-by-count":5,"title":["Effect of continuous positive airway pressure on blood pressure in normotensive individuals with obstructive sleep apnoea: a randomised 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