{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T23:49:32Z","timestamp":1773013772340,"version":"3.50.1"},"reference-count":29,"publisher":"European Respiratory Society (ERS)","issue":"5","content-domain":{"domain":["publications.ersnet.org"],"crossmark-restriction":true},"short-container-title":["Eur Respir J"],"accepted":{"date-parts":[[2016,2,13]]},"published-print":{"date-parts":[[2016,5]]},"abstract":"<jats:p>Low-dose chest computed tomography (LDCT) screening increased detection of airway nodules. Most nodules appear to be secretions, but pathological lesions may show similar findings. The National Comprehensive Cancer Network (NCCN) recommends repeating LDCT after 1\u2005month and proceeding to bronchoscopy if the nodules persist. However, no reports exist about incidentally detected airway nodules. We investigated the significance of airway nodules detected by LDCT screening.<\/jats:p><jats:p>We screened patients with incidental airway nodules detected by LDCT in the Seoul National University Hospital group. The characteristics of computed tomography, bronchoscopy, pathology and clinical findings were analysed.<\/jats:p><jats:p>Among 53\u200a036 individuals who underwent LDCT screening, 313 (0.6%) had airway nodules. Of these, 186 (59.4%) were followed-up with chest computed tomography and\/or bronchoscopy. Seven (3.8%) cases had significant lesions, including leiomyoma (n=2), endobronchial tuberculosis (n=2), chronic inflammation (n=1), hamartoma (n=1) and benign granuloma (n=1). The remaining 179 lesions were transient, suggesting that they were secretions.<\/jats:p><jats:p>The use of LDCT for lung cancer screening demonstrated the low incidence of airway lesions. Most lesions were transient secretions. True pathological lesions were rare, and no malignant lesion was found. The current recommendation of the NCCN guideline is a reasonable approach that can avoid unnecessary bronchoscopy.<\/jats:p>","DOI":"10.1183\/13993003.01992-2015","type":"journal-article","created":{"date-parts":[[2016,3,31]],"date-time":"2016-03-31T03:34:06Z","timestamp":1459395246000},"page":"1510-1517","update-policy":"https:\/\/doi.org\/10.1183\/ers-crossmark-policy","source":"Crossref","is-referenced-by-count":21,"title":["Outcome of incidentally detected airway nodules"],"prefix":"10.1183","volume":"47","author":[{"given":"Hyung-Jun","family":"Kim","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Deog Kyeom","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Young Whan","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yeon Joo","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jong Sun","family":"Park","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Young-Jae","family":"Cho","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Se Joong","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ho Il","family":"Yoon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jae Ho","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Choon-Taek","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"81","published-online":{"date-parts":[[2016,3,30]]},"reference":[{"key":"2024102023582068000_47.5.1510.1","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.176.3.1760707"},{"key":"2024102023582068000_47.5.1510.2","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.05.00120904"},{"key":"2024102023582068000_47.5.1510.3","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijscr.2014.09.017"},{"key":"2024102023582068000_47.5.1510.4","doi-asserted-by":"publisher","DOI":"10.1016\/S1092-9134(97)80007-X"},{"key":"2024102023582068000_47.5.1510.5","doi-asserted-by":"publisher","DOI":"10.1148\/rg.291085126"},{"key":"2024102023582068000_47.5.1510.6","doi-asserted-by":"publisher","DOI":"10.1378\/chest.13-1965"},{"key":"2024102023582068000_47.5.1510.7","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(05)70541-6"},{"key":"2024102023582068000_47.5.1510.8","doi-asserted-by":"publisher","DOI":"10.1016\/j.lungcan.2014.03.005"},{"key":"2024102023582068000_47.5.1510.9","doi-asserted-by":"publisher","DOI":"10.3349\/ymj.2013.54.2.403"},{"key":"2024102023582068000_47.5.1510.10","doi-asserted-by":"crossref","first-page":"553","DOI":"10.3892\/ol.2013.1423","article-title":"Small cell lung cancer with endobronchial growth: a case report","volume":"6","author":"Kurishima","year":"2013","journal-title":"Oncol Lett"},{"key":"2024102023582068000_47.5.1510.11","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2012.5521"},{"key":"2024102023582068000_47.5.1510.12","doi-asserted-by":"crossref","first-page":"330","DOI":"10.7326\/M13-2771","article-title":"Screening for lung cancer: U.S. Preventive Services Task Force recommendation statement","volume":"160","author":"Moyer","year":"2014","journal-title":"Ann Intern Med"},{"key":"2024102023582068000_47.5.1510.13","unstructured":"Network NCC. 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