{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,3]],"date-time":"2026-04-03T10:32:06Z","timestamp":1775212326227,"version":"3.50.1"},"reference-count":41,"publisher":"European Respiratory Society (ERS)","issue":"6","funder":[{"name":"Ministerio de Educaci\u00f3n y Ciencia","award":["SAF2007-62270"],"award-info":[{"award-number":["SAF2007-62270"]}]},{"name":"Ministerio de Econom\u00eda y Competitividad","award":["PI10\/00495"],"award-info":[{"award-number":["PI10\/00495"]}]},{"name":"SEPAR","award":["2010-820"],"award-info":[{"award-number":["2010-820"]}]},{"name":"Neumomadrid","award":["2009"],"award-info":[{"award-number":["2009"]}]},{"name":"Direcci\u00f3 General d'Avaluaci\u00f3 i Acreditaci\u00f3. Conselleria de Salut i Consum. 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We also measured basic biochemical profile and haemogram, and coagulation biomarkers (D-dimer, prothrombin fragment 1+2, thrombin-antithrombin complex, plasminogen activator inhibitor 1, and soluble P-selectin).<\/jats:p><jats:p>64 (74.4%) of the pulmonary embolism cases and 41 (46.11%) of the controls without pulmonary embolism had obstructive sleep apnoea. Plasmatic D-dimer was higher in PE patients with OSA than in those without obstructive sleep apnoea. D-dimer levels were significantly correlated with apnoea\u2013hypopnoea index, and nocturnal hypoxia. There were more patients with high D-dimer after stopping anticoagulants in those with pulmonary embolism and obstructive sleep apnoea compared with PE without obstructive sleep apnoea (35.4%<jats:italic>versus<\/jats:italic>19.0%, p=0.003). Apnoea\u2013hypopnoea index was independently associated with high D-dimer.<\/jats:p><jats:p>Pulmonary embolism patients with obstructive sleep apnoea had higher rates of elevated D-dimer levels after anticoagulation discontinuation for pulmonary embolism than in patients without obstructive sleep apnoea and, therefore, higher procoagulant state that might increase the risk of pulmonary embolism recurrence.<\/jats:p>","DOI":"10.1183\/13993003.02041-2014","type":"journal-article","created":{"date-parts":[[2015,8,6]],"date-time":"2015-08-06T19:23:44Z","timestamp":1438889024000},"page":"1691-1700","update-policy":"https:\/\/doi.org\/10.1183\/ers-crossmark-policy","source":"Crossref","is-referenced-by-count":25,"title":["High D-dimer levels after stopping anticoagulants in pulmonary embolism with sleep apnoea"],"prefix":"10.1183","volume":"46","author":[{"given":"Angela","family":"Garc\u00eda 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