{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T17:43:29Z","timestamp":1790790209802,"version":"4.1.0"},"reference-count":143,"publisher":"European Respiratory Society (ERS)","issue":"141","content-domain":{"domain":["publications.ersnet.org"],"crossmark-restriction":true},"short-container-title":["Eur Respir Rev"],"accepted":{"date-parts":[[2016,6,13]]},"published-print":{"date-parts":[[2016,9]]},"abstract":"<jats:p>Exertional dyspnoea is among the dominant symptoms in patients with chronic heart failure and progresses relentlessly as the disease advances, leading to reduced ability to function and engage in activities of daily living. Effective management of this disabling symptom awaits a better understanding of its underlying physiology.<\/jats:p><jats:p>Cardiovascular factors are believed to play a major role in dyspnoea in heart failure patients. However, despite pharmacological interventions, such as vasodilators or inotropes that improve central haemodynamics, patients with heart failure still complain of exertional dyspnoea. Clearly, dyspnoea is not determined by cardiac factors alone, but likely depends on complex, integrated cardio-pulmonary interactions.<\/jats:p><jats:p>A growing body of evidence suggests that excessively increased ventilatory demand and abnormal \u201crestrictive\u201d constraints on tidal volume expansion with development of critical mechanical limitation of ventilation, contribute to exertional dyspnoea in heart failure. This article will offer new insights into the pathophysiological mechanisms of exertional dyspnoea in patients with chronic heart failure by exploring the potential role of the various constituents of the physiological response to exercise and particularly the role of abnormal ventilatory and respiratory mechanics responses to exercise in the perception of dyspnoea in patients with heart failure.<\/jats:p>","DOI":"10.1183\/16000617.0048-2016","type":"journal-article","created":{"date-parts":[[2016,9,1]],"date-time":"2016-09-01T01:06:50Z","timestamp":1472692010000},"page":"317-332","update-policy":"https:\/\/doi.org\/10.1183\/ers-crossmark-policy","source":"Crossref","is-referenced-by-count":74,"title":["Exertional dyspnoea in chronic heart failure: the role of the lung and respiratory mechanical factors"],"prefix":"10.1183","volume":"25","author":[{"given":"Bruno-Pierre","family":"Dub\u00e9","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Piergiuseppe","family":"Agostoni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pierantonio","family":"Laveneziana","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"81","published-online":{"date-parts":[[2016,8,31]]},"reference":[{"key":"2024102403224902000_25.141.317.1","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0000000000000350"},{"key":"2024102403224902000_25.141.317.2","doi-asserted-by":"publisher","DOI":"10.1002\/ehf2.12005"},{"key":"2024102403224902000_25.141.317.3","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.00092613"},{"key":"2024102403224902000_25.141.317.4","doi-asserted-by":"publisher","DOI":"10.1097\/MCP.0000000000000134"},{"key":"2024102403224902000_25.141.317.5","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.160.6.9808134"},{"key":"2024102403224902000_25.141.317.6","doi-asserted-by":"publisher","DOI":"10.1152\/japplphysiol.90744.2008"},{"key":"2024102403224902000_25.141.317.7","doi-asserted-by":"publisher","DOI":"10.1016\/0735-1097(93)90685-T"},{"key":"2024102403224902000_25.141.317.8","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/16.suppl_E.49"},{"key":"2024102403224902000_25.141.317.9","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.152.6.8520771"},{"key":"2024102403224902000_25.141.317.10","doi-asserted-by":"publisher","DOI":"10.1378\/chest.110.5.1255"},{"key":"2024102403224902000_25.141.317.11","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-8703(98)70314-X"},{"key":"2024102403224902000_25.141.317.12","doi-asserted-by":"publisher","DOI":"10.1111\/j.1445-5994.1988.tb02252.x"},{"key":"2024102403224902000_25.141.317.13","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.1977.sp012066"},{"key":"2024102403224902000_25.141.317.14","doi-asserted-by":"publisher","DOI":"10.1016\/0014-4886(74)90019-3"},{"key":"2024102403224902000_25.141.317.15","first-page":"H770","article-title":"Role of diprotonated phosphate in evoking muscle reflex responses in cats and humans","volume":"267","author":"Sinoway","year":"1994","journal-title":"Am J Physiol"},{"key":"2024102403224902000_25.141.317.16","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.55.5.439"},{"key":"2024102403224902000_25.141.317.17","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.2003.026567"},{"key":"2024102403224902000_25.141.317.18","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2015.03.422"},{"key":"2024102403224902000_25.141.317.19","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0087395"},{"key":"2024102403224902000_25.141.317.20","doi-asserted-by":"publisher","DOI":"10.1378\/chest.106.6.1746"},{"key":"2024102403224902000_25.141.317.21","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.89.5.2062"},{"key":"2024102403224902000_25.141.317.22","doi-asserted-by":"crossref","first-page":"749","DOI":"10.1093\/oxfordjournals.eurheartj.a060251","article-title":"Abnormal diastolic filling patterns in chronic heart failure: relationship to exercise capacity","volume":"13","author":"Davies","year":"1992","journal-title":"Eur Heart J"},{"key":"2024102403224902000_25.141.317.23","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9149(83)80010-1"},{"key":"2024102403224902000_25.141.317.24","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.2003.025684"},{"key":"2024102403224902000_25.141.317.25","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.61.5.955"},{"key":"2024102403224902000_25.141.317.26","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(81)90286-1"},{"key":"2024102403224902000_25.141.317.27","doi-asserted-by":"publisher","DOI":"10.1016\/0735-1097(95)80018-C"},{"key":"2024102403224902000_25.141.317.28","doi-asserted-by":"publisher","DOI":"10.1093\/ehjci\/jes096"},{"key":"2024102403224902000_25.141.317.29","doi-asserted-by":"publisher","DOI":"10.1016\/0735-1097(90)90174-N"},{"key":"2024102403224902000_25.141.317.30","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(85)90742-8"},{"key":"2024102403224902000_25.141.317.31","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(86)90340-2"},{"key":"2024102403224902000_25.141.317.32","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(84)90085-7"},{"key":"2024102403224902000_25.141.317.33","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(79)90368-0"},{"key":"2024102403224902000_25.141.317.34","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2013.2024"},{"key":"2024102403224902000_25.141.317.35","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.95.7.1930"},{"key":"2024102403224902000_25.141.317.36","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehi023"},{"key":"2024102403224902000_25.141.317.37","doi-asserted-by":"publisher","DOI":"10.1016\/j.cardfail.2010.02.006"},{"key":"2024102403224902000_25.141.317.38","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2013.01.277"},{"key":"2024102403224902000_25.141.317.39","doi-asserted-by":"publisher","DOI":"10.1067\/mhj.2000.110282"},{"key":"2024102403224902000_25.141.317.40","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehl302"},{"key":"2024102403224902000_25.141.317.41","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.101.24.2803"},{"key":"2024102403224902000_25.141.317.42","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.77.2.138"},{"key":"2024102403224902000_25.141.317.43","doi-asserted-by":"publisher","DOI":"10.1016\/0167-5273(94)02267-M"},{"key":"2024102403224902000_25.141.317.44","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.96.7.2221"},{"key":"2024102403224902000_25.141.317.45","doi-asserted-by":"publisher","DOI":"10.1016\/0735-1097(93)90096-J"},{"key":"2024102403224902000_25.141.317.46","doi-asserted-by":"publisher","DOI":"10.1016\/j.cardfail.2005.06.430"},{"key":"2024102403224902000_25.141.317.47","doi-asserted-by":"publisher","DOI":"10.1152\/japplphysiol.00724.2001"},{"key":"2024102403224902000_25.141.317.48","doi-asserted-by":"publisher","DOI":"10.1172\/JCI100589"},{"key":"2024102403224902000_25.141.317.49","doi-asserted-by":"publisher","DOI":"10.1136\/thx.50.3.245"},{"key":"2024102403224902000_25.141.317.50","doi-asserted-by":"publisher","DOI":"10.1172\/JCI103316"},{"key":"2024102403224902000_25.141.317.51","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(57)90106-7"},{"key":"2024102403224902000_25.141.317.52","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1159\/000194886","article-title":"Pulmonary function tests in the detection of left heart failure: correlation with pulmonary artery wedge pressure","volume":"49","author":"Ries","year":"1986","journal-title":"Respiration"},{"key":"2024102403224902000_25.141.317.53","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(99)00627-0"},{"key":"2024102403224902000_25.141.317.54","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198905183202005"},{"key":"2024102403224902000_25.141.317.55","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.1983.00350030039007"},{"key":"2024102403224902000_25.141.317.56","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-8703(99)70148-1"},{"key":"2024102403224902000_25.141.317.57","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.85.5.1751"},{"key":"2024102403224902000_25.141.317.58","first-page":"A418","article-title":"Ventilatory constraints contribute to exercise limitation and dyspnea in stable congestive heart failure","volume":"159","author":"D'Arsigny","year":"1999","journal-title":"Am J Respir Crit Care Med"},{"key":"2024102403224902000_25.141.317.59","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9149(99)80229-X"},{"key":"2024102403224902000_25.141.317.60","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2006.04.091"},{"key":"2024102403224902000_25.141.317.61","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2005.09.052"},{"key":"2024102403224902000_25.141.317.62","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.2006.117614"},{"key":"2024102403224902000_25.141.317.63","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/14.6.744"},{"key":"2024102403224902000_25.141.317.64","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.91520.2007"},{"key":"2024102403224902000_25.141.317.65","doi-asserted-by":"publisher","DOI":"10.1378\/chest.123.5.1386"},{"key":"2024102403224902000_25.141.317.66","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.77.3.552"},{"key":"2024102403224902000_25.141.317.67","doi-asserted-by":"publisher","DOI":"10.1016\/0002-8703(93)90173-7"},{"key":"2024102403224902000_25.141.317.68","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(92)90202-A"},{"key":"2024102403224902000_25.141.317.69","doi-asserted-by":"crossref","first-page":"1007","DOI":"10.1016\/0002-9149(93)90927-5","article-title":"Exercise hyperventilation chronic congestive heart failure and its relation to functional capacity and hemodynamics","volume":"71","author":"Clark","year":"1993","journal-title":"Am J Cardiol"},{"key":"2024102403224902000_25.141.317.70","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.71.6.528"},{"key":"2024102403224902000_25.141.317.71","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.91.11.2769"},{"key":"2024102403224902000_25.141.317.72","doi-asserted-by":"publisher","DOI":"10.1161\/01.HYP.34.6.1202"},{"key":"2024102403224902000_25.141.317.73","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000097115.61309.59"},{"key":"2024102403224902000_25.141.317.74","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0061877"},{"key":"2024102403224902000_25.141.317.75","doi-asserted-by":"publisher","DOI":"10.1152\/japplphysiol.00108.2004"},{"key":"2024102403224902000_25.141.317.76","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(00)00929-3"},{"key":"2024102403224902000_25.141.317.77","doi-asserted-by":"publisher","DOI":"10.1002\/path.1711110404"},{"key":"2024102403224902000_25.141.317.78","doi-asserted-by":"publisher","DOI":"10.1053\/euhj.2001.2803"},{"key":"2024102403224902000_25.141.317.79","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9149(99)00495-6"},{"key":"2024102403224902000_25.141.317.80","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-8703(96)90333-6"},{"key":"2024102403224902000_25.141.317.81","doi-asserted-by":"crossref","first-page":"1264","DOI":"10.1152\/jappl.1999.86.4.1264","article-title":"Enhanced peripheral chemoreflex function in conscious rabbits with pacing-induced heart failure","volume":"86","author":"Sun","year":"1999","journal-title":"J Appl Physiol"},{"key":"2024102403224902000_25.141.317.82","doi-asserted-by":"publisher","DOI":"10.1063\/1.370881"},{"key":"2024102403224902000_25.141.317.83","doi-asserted-by":"publisher","DOI":"10.1016\/0735-1097(95)00523-4"},{"key":"2024102403224902000_25.141.317.84","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.eurheartj.a015269"},{"key":"2024102403224902000_25.141.317.85","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.65.6.1213"},{"key":"2024102403224902000_25.141.317.86","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(84)90696-9"},{"key":"2024102403224902000_25.141.317.87","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(97)00078-8"},{"key":"2024102403224902000_25.141.317.88","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.103.7.916"},{"key":"2024102403224902000_25.141.317.89","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.103.7.967"},{"key":"2024102403224902000_25.141.317.90","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.93.5.940"},{"key":"2024102403224902000_25.141.317.91","doi-asserted-by":"publisher","DOI":"10.1080\/07853890410017467"},{"key":"2024102403224902000_25.141.317.92","first-page":"191","article-title":"Cardiac Cachexia: Pathophysiology and Clinical Implications","volume":"13","author":"Steinborn","year":"2003","journal-title":"Basic Appl Myol"},{"key":"2024102403224902000_25.141.317.93","doi-asserted-by":"publisher","DOI":"10.1111\/j.1527-5299.2002.01219.x"},{"key":"2024102403224902000_25.141.317.94","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1152\/jappl.1993.75.1.373","article-title":"Skeletal muscle size: relationship to muscle function in heart failure","volume":"75","author":"Minotti","year":"1993","journal-title":"J Appl Physiol"},{"key":"2024102403224902000_25.141.317.95","doi-asserted-by":"publisher","DOI":"10.2174\/157340308784245757"},{"key":"2024102403224902000_25.141.317.96","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.eurheartj.a015386"},{"key":"2024102403224902000_25.141.317.97","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.81.2.518"},{"key":"2024102403224902000_25.141.317.98","doi-asserted-by":"publisher","DOI":"10.1016\/0167-5273(88)90164-7"},{"key":"2024102403224902000_25.141.317.99","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.78.2.320"},{"key":"2024102403224902000_25.141.317.100","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.76.5.1009"},{"key":"2024102403224902000_25.141.317.101","doi-asserted-by":"publisher","DOI":"10.1053\/euhj.1998.1446"},{"key":"2024102403224902000_25.141.317.102","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(02)01736-9"},{"key":"2024102403224902000_25.141.317.103","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(98)00226-5"},{"key":"2024102403224902000_25.141.317.104","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1093\/oxfordjournals.eurheartj.a060588","article-title":"Predictors of exercise capacity in chronic heart failure","volume":"15","author":"Volterrani","year":"1994","journal-title":"Eur Heart J"},{"key":"2024102403224902000_25.141.317.105","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.87.2.470"},{"key":"2024102403224902000_25.141.317.106","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(02)01740-0"},{"key":"2024102403224902000_25.141.317.107","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.76.4.337"},{"key":"2024102403224902000_25.141.317.108","doi-asserted-by":"crossref","first-page":"1811","DOI":"10.1152\/jappl.1997.82.6.1811","article-title":"Responses of group III and IV muscle afferents to dynamic exercise","volume":"82","author":"Adreani","year":"1997","journal-title":"J Appl Physiol"},{"key":"2024102403224902000_25.141.317.109","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.105.605980"},{"key":"2024102403224902000_25.141.317.110","doi-asserted-by":"publisher","DOI":"10.1161\/hc4401.098491"},{"key":"2024102403224902000_25.141.317.111","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1111\/j.1469-7793.2000.00863.x","article-title":"Contribution of skeletal muscle \u2018ergoreceptors\u2019 in the human leg to respiratory control in chronic heart failure","volume":"529 Pt 3","author":"Scott","year":"2000","journal-title":"J Physiol"},{"key":"2024102403224902000_25.141.317.112","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.85.6.2119"},{"key":"2024102403224902000_25.141.317.113","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.160.2.9810081"},{"key":"2024102403224902000_25.141.317.114","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.153.1.8542129"},{"key":"2024102403224902000_25.141.317.115","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.81.6.618"},{"key":"2024102403224902000_25.141.317.116","doi-asserted-by":"publisher","DOI":"10.1378\/chest.98.5.1091"},{"key":"2024102403224902000_25.141.317.117","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm\/146.2.467"},{"key":"2024102403224902000_25.141.317.118","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.94.07010017"},{"key":"2024102403224902000_25.141.317.119","doi-asserted-by":"publisher","DOI":"10.1378\/chest.105.2.355"},{"key":"2024102403224902000_25.141.317.120","doi-asserted-by":"publisher","DOI":"10.1136\/thx.50.6.625"},{"key":"2024102403224902000_25.141.317.121","doi-asserted-by":"crossref","first-page":"e28944","DOI":"10.5812\/cardiovascmed.28944","article-title":"The relation of respiratory muscle strength to disease severity and abnormal ventilation during exercise in chronic heart failure patients","volume":"4","author":"Kasahara","year":"2015","journal-title":"Res Cardiovasc Med"},{"key":"2024102403224902000_25.141.317.122","doi-asserted-by":"publisher","DOI":"10.1097\/HJR.0b013e3282f0d6ea"},{"key":"2024102403224902000_25.141.317.123","doi-asserted-by":"publisher","DOI":"10.1016\/j.resp.2010.01.009"},{"key":"2024102403224902000_25.141.317.124","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1111\/j.1469-7793.2000.00493.x","article-title":"Fatiguing inspiratory muscle work causes reflex sympathetic activation in humans","volume":"529 Pt 2","author":"St Croix","year":"2000","journal-title":"J Physiol"},{"key":"2024102403224902000_25.141.317.125","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.86.3.909"},{"key":"2024102403224902000_25.141.317.126","first-page":"H1721","article-title":"Elevated diaphragmatic blood flow during submaximal exercise in rats with chronic heart failure","volume":"265","author":"Musch","year":"1993","journal-title":"Am J Physiol"},{"key":"2024102403224902000_25.141.317.127","doi-asserted-by":"publisher","DOI":"10.1378\/chest.117.2.321"},{"key":"2024102403224902000_25.141.317.128","first-page":"499","article-title":"Respiratory muscle fatigue during cardiogenic shock","volume":"51","author":"Aubier","year":"1981","journal-title":"J Appl Physiol Respir Environ Exerc Physiol"},{"key":"2024102403224902000_25.141.317.129","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.100.5.503"},{"key":"2024102403224902000_25.141.317.130","doi-asserted-by":"publisher","DOI":"10.1016\/0735-1097(94)90858-3"},{"key":"2024102403224902000_25.141.317.131","doi-asserted-by":"crossref","first-page":"2707","DOI":"10.1152\/jappl.1994.76.6.2707","article-title":"Alterations in diaphragm strength and fatiguability in congestive heart failure","volume":"76","author":"Supinski","year":"1994","journal-title":"J Appl Physiol"},{"key":"2024102403224902000_25.141.317.132","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.155.2.9032185"},{"key":"2024102403224902000_25.141.317.133","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.155.2.9032205"},{"key":"2024102403224902000_25.141.317.134","doi-asserted-by":"crossref","first-page":"2539","DOI":"10.1152\/jappl.1989.66.6.2539","article-title":"Diaphragm motor unit recruitment during ventilatory and nonventilatory behaviors","volume":"66","author":"Sieck","year":"1989","journal-title":"J Appl Physiol"},{"key":"2024102403224902000_25.141.317.135","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.95.4.910"},{"key":"2024102403224902000_25.141.317.136","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.eurheartj.a015042"},{"key":"2024102403224902000_25.141.317.137","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1152\/jappl.1995.79.2.389","article-title":"Congestive heart failure: differential adaptation of the diaphragm and latissimus dorsi","volume":"79","author":"Howell","year":"1995","journal-title":"J Appl Physiol"},{"key":"2024102403224902000_25.141.317.138","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199612193352507"},{"key":"2024102403224902000_25.141.317.139","doi-asserted-by":"publisher","DOI":"10.1016\/0735-1097(91)90605-9"},{"key":"2024102403224902000_25.141.317.140","doi-asserted-by":"publisher","DOI":"10.1253\/jcj.63.97"},{"key":"2024102403224902000_25.141.317.141","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.91.2.320"},{"key":"2024102403224902000_25.141.317.142","doi-asserted-by":"publisher","DOI":"10.1053\/euhj.1998.1024"},{"key":"2024102403224902000_25.141.317.143","doi-asserted-by":"crossref","first-page":"768","DOI":"10.1016\/j.ahj.2009.09.005","article-title":"Addition of inspiratory muscle training to aerobic training improves cardiorespiratory responses to exercise in patients with heart failure and inspiratory muscle weakness","volume":"158","author":"Winkelmann","year":"2009","journal-title":"Am Heart J"}],"container-title":["European Respiratory Review"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1183\/16000617.0048-2016","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,24]],"date-time":"2025-02-24T04:58:58Z","timestamp":1740373138000},"score":1,"resource":{"primary":{"URL":"https:\/\/publications.ersnet.org\/lookup\/doi\/10.1183\/16000617.0048-2016"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,8,31]]},"references-count":143,"journal-issue":{"issue":"141","published-online":{"date-parts":[[2016,8,31]]},"published-print":{"date-parts":[[2016,9]]}},"alternative-id":["10.1183\/16000617.0048-2016"],"URL":"https:\/\/doi.org\/10.1183\/16000617.0048-2016","relation":{},"ISSN":["0905-9180","1600-0617"],"issn-type":[{"value":"0905-9180","type":"print"},{"value":"1600-0617","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,8,31]]}}}