{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T05:32:57Z","timestamp":1792128777230,"version":"4.4.0"},"reference-count":33,"publisher":"European Respiratory Society (ERS)","issue":"153","license":[{"start":{"date-parts":[[2019,9,30]],"date-time":"2019-09-30T00:00:00Z","timestamp":1569801600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["publications.ersnet.org"],"crossmark-restriction":true},"short-container-title":["Eur Respir Rev"],"accepted":{"date-parts":[[2019,9,5]]},"published-print":{"date-parts":[[2019,9,30]]},"abstract":"<jats:p>Both obstructive sleep apnoea (OSA) and chronic insomnia disorder are highly prevalent in the general population. Whilst both disorders may occur together by mere coincidence, it appears that they share clinical features and that they may aggravate each other as a result of reciprocally adverse pathogenetic mechanisms. Comorbidity between chronic insomnia disorder and OSA is a clinically relevant condition that may confront practitioners with serious diagnostic and therapeutic challenges. Current data, while still scarce, advocate an integrated and multidisciplinary approach that seems superior over the isolated treatment of each sleep disorder alone.<\/jats:p>","DOI":"10.1183\/16000617.0080-2019","type":"journal-article","created":{"date-parts":[[2019,10,9]],"date-time":"2019-10-09T14:59:12Z","timestamp":1570633152000},"page":"190080","update-policy":"https:\/\/doi.org\/10.1183\/ers-crossmark-policy","source":"Crossref","is-referenced-by-count":51,"title":["Management of insomnia in sleep disordered breathing"],"prefix":"10.1183","volume":"28","author":[{"given":"Hennie C.J.P.","family":"Janssen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lisette N.","family":"Venekamp","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Geert A.M.","family":"Peeters","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angelique","family":"Pijpers","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dirk A.A.","family":"Pevernagie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"81","published-online":{"date-parts":[[2019,10,9]]},"reference":[{"key":"2024102403411712000_28.153.190080.1","unstructured":"Chronic insomnia disorder. In: Sateia M , ed. The International Classification of Sleep Disorders . 3rd Edn. Darien, American Academy of Sleep Medicine, 2014; pp. 21\u201341."},{"key":"2024102403411712000_28.153.190080.2","unstructured":"Obstructive sleep apnea: adult. In: Sateia M , ed. The International Classification of Sleep Disorders . 3rd Edn. Darien, American Academy of Sleep Medicine, 2014; pp. 53\u201362."},{"key":"2024102403411712000_28.153.190080.3","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1016\/S2213-2600(15)00043-0","article-title":"Prevalence of sleep-disordered breathing in the general population: the HypnoLaus study","volume":"3","author":"Heinzer","year":"2015","journal-title":"Lancet Respir Med"},{"key":"2024102403411712000_28.153.190080.4","doi-asserted-by":"crossref","first-page":"e5","DOI":"10.1016\/S2213-2600(16)00006-0","article-title":"Prevalence of sleep apnoea syndrome in the middle to old age general population","volume":"4","author":"Heinzer","year":"2016","journal-title":"Lancet Respir Med"},{"key":"2024102403411712000_28.153.190080.5","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.98.12061264"},{"key":"2024102403411712000_28.153.190080.6","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.00225113"},{"key":"2024102403411712000_28.153.190080.7","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/j.smrv.2017.03.002","article-title":"To screen or not to screen for obstructive sleep apnea, that is the question","volume":"36","author":"Turnbull","year":"2017","journal-title":"Sleep Med Rev"},{"key":"2024102403411712000_28.153.190080.8","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1606599"},{"key":"2024102403411712000_28.153.190080.9","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1016\/S2213-2600(18)30059-6","article-title":"Challenges in obstructive sleep apnoea","volume":"6","author":"McNicholas","year":"2018","journal-title":"Lancet Respir Med"},{"key":"2024102403411712000_28.153.190080.10","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.smrv.2019.01.004","article-title":"Worldwide and regional prevalence rates of co-occurrence of insomnia and insomnia symptoms with obstructive sleep apnea: a systematic review and meta-analysis","volume":"45","author":"Zhang","year":"2019","journal-title":"Sleep Med Rev"},{"key":"2024102403411712000_28.153.190080.11","doi-asserted-by":"crossref","first-page":"196","DOI":"10.5664\/jcsm.27772","article-title":"Comorbid insomnia and obstructive sleep apnea: challenges for clinical practice and research","volume":"6","author":"Luyster","year":"2010","journal-title":"J Clin Sleep Med"},{"key":"2024102403411712000_28.153.190080.12","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.00032314"},{"key":"2024102403411712000_28.153.190080.13","doi-asserted-by":"crossref","unstructured":"Keenan BT , Kim J , Singh B , et al. Recognizable clinical subtypes of obstructive sleep apnea across international sleep centers: a cluster analysis. Sleep 2018; 41: https:\/\/doi.org\/10.1093\/sleep\/zsx214.","DOI":"10.1093\/sleep\/zsx214"},{"key":"2024102403411712000_28.153.190080.14","doi-asserted-by":"crossref","first-page":"e90021","DOI":"10.1371\/journal.pone.0090021","article-title":"Cardiovascular and psychiatric morbidity in obstructive sleep apnea (OSA) with insomnia (sleep apnea plus) versus obstructive sleep apnea without insomnia: a case\u2013control study from a Nationally Representative US sample","volume":"9","author":"Gupta","year":"2014","journal-title":"PLoS One"},{"key":"2024102403411712000_28.153.190080.15","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1016\/j.smrv.2016.04.004","article-title":"Developing a successful treatment for co-morbid insomnia and sleep apnoea","volume":"33","author":"Sweetman","year":"2017","journal-title":"Sleep Med Rev"},{"key":"2024102403411712000_28.153.190080.16","doi-asserted-by":"crossref","first-page":"899","DOI":"10.1016\/j.sleep.2014.05.001","article-title":"Predictors and patterns of insomnia symptoms in OSA before and after PAP therapy","volume":"15","author":"Glidewell","year":"2014","journal-title":"Sleep Med"},{"key":"2024102403411712000_28.153.190080.17","doi-asserted-by":"crossref","unstructured":"Pien GW , Ye L , Keenan BT , et al. Changing faces of obstructive sleep apnea: treatment effects by cluster designation in the Icelandic Sleep Apnea Cohort. Sleep 2018; 41: https:\/\/doi.org\/10.1093\/sleep\/zsx201.","DOI":"10.1093\/sleep\/zsx201"},{"key":"2024102403411712000_28.153.190080.18","doi-asserted-by":"crossref","first-page":"1901","DOI":"10.5665\/sleep.3226","article-title":"Symptoms of insomnia among patients with obstructive sleep apnea before and after two years of positive airway pressure treatment","volume":"36","author":"Bjornsdottir","year":"2013","journal-title":"Sleep"},{"key":"2024102403411712000_28.153.190080.19","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201303-0448OC"},{"key":"2024102403411712000_28.153.190080.20","doi-asserted-by":"crossref","unstructured":"Eckert DJ , Wellman A . Physiological phenotypes. In: Barb\u00e9 F , P\u00e9pin JL , eds. Obstructive Sleep Apnoea (ERS Monograph) . Sheffield, European Respiratory Society, 2015; pp. 9\u201323.","DOI":"10.1183\/2312508X.10005414"},{"key":"2024102403411712000_28.153.190080.21","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.2005.083659"},{"key":"2024102403411712000_28.153.190080.22","doi-asserted-by":"publisher","DOI":"10.1042\/CS20100588"},{"key":"2024102403411712000_28.153.190080.23","doi-asserted-by":"crossref","first-page":"811","DOI":"10.5665\/sleep.3596","article-title":"Trazodone increases the respiratory arousal threshold in patients with obstructive sleep apnea and a low arousal threshold","volume":"37","author":"Eckert","year":"2014","journal-title":"Sleep"},{"key":"2024102403411712000_28.153.190080.24","doi-asserted-by":"crossref","first-page":"804","DOI":"10.3389\/fneur.2018.00804","article-title":"Current treatment of comorbid insomnia and obstructive sleep apnea with CBTI and PAP-therapy: a systematic review","volume":"9","author":"Bahr","year":"2018","journal-title":"Front Neurol"},{"key":"2024102403411712000_28.153.190080.25","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1111\/jsr.12046","article-title":"The subjective-objective mismatch in sleep perception among those with insomnia and sleep apnea","volume":"22","author":"Bianchi","year":"2013","journal-title":"J Sleep Res"},{"key":"2024102403411712000_28.153.190080.26","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1111\/jsr.12482","article-title":"Insomnia complaints in lean patients with obstructive sleep apnea negatively affect positive airway pressure treatment adherence","volume":"26","author":"Eysteinsdottir","year":"2017","journal-title":"J Sleep Res"},{"key":"2024102403411712000_28.153.190080.27","doi-asserted-by":"crossref","first-page":"e0195343","DOI":"10.1371\/journal.pone.0195343","article-title":"Specific insomnia symptoms and self-efficacy explain CPAP compliance in a sample of OSAS patients","volume":"13","author":"Philip","year":"2018","journal-title":"PLoS One"},{"key":"2024102403411712000_28.153.190080.28","doi-asserted-by":"crossref","first-page":"1513","DOI":"10.3389\/fphar.2018.01513","article-title":"Benzodiazepines associated with acute respiratory failure in patients with obstructive sleep apnea","volume":"9","author":"Wang","year":"2018","journal-title":"Front Pharmacol"},{"key":"2024102403411712000_28.153.190080.29","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.01955-2015"},{"key":"2024102403411712000_28.153.190080.30","doi-asserted-by":"crossref","unstructured":"Pevernagie DA . Insomnia. In: Simonds AK , de Backer W , eds. ERS Handbook of Respiratory Sleep Medicine . Sheffield, European Respiratory Society, 2012; pp. 53\u201360.","DOI":"10.1183\/9781849840248.015111"},{"key":"2024102403411712000_28.153.190080.31","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1111\/jsr.12594","article-title":"European guideline for the diagnosis and treatment of insomnia","volume":"26","author":"Riemann","year":"2017","journal-title":"J Sleep Res"},{"key":"2024102403411712000_28.153.190080.32","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1016\/j.sleep.2017.09.003","article-title":"Does comorbid obstructive sleep apnea impair the effectiveness of cognitive and behavioral therapy for insomnia?","volume":"39","author":"Sweetman","year":"2017","journal-title":"Sleep Med"},{"key":"2024102403411712000_28.153.190080.33","doi-asserted-by":"crossref","unstructured":"Sweetman A , Lack L , Catcheside PG , et al. Cognitive and behavioral therapy for insomnia increases the use of continuous positive airway pressure therapy in obstructive sleep apnea participants with co-morbid insomnia: A randomized clinical trial. Sleep 2019; https:\/\/doi.org\/10.1093\/sleep\/zsz178.","DOI":"10.1093\/sleep\/zsz178"}],"container-title":["European Respiratory Review"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1183\/16000617.0080-2019","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,24]],"date-time":"2025-02-24T05:01:13Z","timestamp":1740373273000},"score":1,"resource":{"primary":{"URL":"https:\/\/publications.ersnet.org\/lookup\/doi\/10.1183\/16000617.0080-2019"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,9,30]]},"references-count":33,"journal-issue":{"issue":"153","published-online":{"date-parts":[[2019,10,9]]},"published-print":{"date-parts":[[2019,9,30]]}},"alternative-id":["10.1183\/16000617.0080-2019"],"URL":"https:\/\/doi.org\/10.1183\/16000617.0080-2019","relation":{},"ISSN":["0905-9180","1600-0617"],"issn-type":[{"value":"0905-9180","type":"print"},{"value":"1600-0617","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,9,30]]}}}