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Optimal treatment is still debated and well-conducted studies regarding efficacy and impact on outcomes of available treatment options are limited, particularly in cardiac failure with preserved ejection fraction. While continuous positive airway pressure and oxygen reduce breathing disturbances by 50%, adaptive servoventilation (ASV) normalises breathing disturbances by to controlling the underlying mechanism of CSA. Results are contradictory regarding impact of ASV on hard outcomes. Cohorts and registry studies show survival improvement under ASV, while secondary analyses of the large SERVE-HF randomised trial showed an excess mortality in cardiac failure with reduced ejection fraction. The current priority is to understand which phenotypes of cardiac failure patients may benefit from treatment guiding individualised and personalised management.<\/jats:p>","DOI":"10.1183\/16000617.0084-2019","type":"journal-article","created":{"date-parts":[[2019,10,11]],"date-time":"2019-10-11T17:55:14Z","timestamp":1570816514000},"page":"190084","update-policy":"https:\/\/doi.org\/10.1183\/ers-crossmark-policy","source":"Crossref","is-referenced-by-count":28,"title":["Central sleep apnoea and periodic breathing in heart failure: prognostic significance and treatment options"],"prefix":"10.1183","volume":"28","author":[{"given":"Winfried","family":"Randerath","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oana Claudia","family":"Deleanu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sofia","family":"Schiza","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Louis","family":"Pepin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"81","published-online":{"date-parts":[[2019,10,11]]},"reference":[{"key":"2024102403412701000_28.153.190084.1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehw128"},{"key":"2024102403412701000_28.153.190084.2","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.00959-2016"},{"key":"2024102403412701000_28.153.190084.3","doi-asserted-by":"publisher","DOI":"10.1016\/j.jchf.2015.09.014"},{"key":"2024102403412701000_28.153.190084.4","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.116.005899"},{"key":"2024102403412701000_28.153.190084.5","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehq327"},{"key":"2024102403412701000_28.153.190084.6","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehu522"},{"key":"2024102403412701000_28.153.190084.7","doi-asserted-by":"publisher","DOI":"10.1378\/chest.06.2287"},{"key":"2024102403412701000_28.153.190084.8","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1080\/17476348.2019.1604226","article-title":"Diagnosis and management of central sleep apnea syndrome","volume":"13","author":"Baillieul","year":"2019","journal-title":"Expert Rev Respir Med"},{"issue":"Suppl. 4","key":"2024102403412701000_28.153.190084.9","first-page":"S220","article-title":"Central sleep apnea and chronic heart failure","volume":"23","author":"Andreas","year":"2000","journal-title":"Sleep"},{"key":"2024102403412701000_28.153.190084.10","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000065227.04025.C2"},{"key":"2024102403412701000_28.153.190084.11","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1007\/s11897-009-0024-6","article-title":"Sleep-disordered breathing in acute decompensated heart failure","volume":"6","author":"Jelic","year":"2009","journal-title":"Curr Heart Fail Rep"},{"key":"2024102403412701000_28.153.190084.12","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9149(99)00462-2"},{"key":"2024102403412701000_28.153.190084.13","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.105.543173"},{"key":"2024102403412701000_28.153.190084.14","doi-asserted-by":"publisher","DOI":"10.1378\/chest.07-0121"},{"key":"2024102403412701000_28.153.190084.15","first-page":"1266","article-title":"Resolution of exercise oscillatory ventilation with adaptive servoventilation in patients with chronic heart failure and Cheyne-Stokes respiration: preliminary study","volume":"69","author":"Kazimierczak","year":"2011","journal-title":"Kardiol Pol"},{"key":"2024102403412701000_28.153.190084.16","doi-asserted-by":"publisher","DOI":"10.1136\/thoraxjnl-2011-200927"},{"key":"2024102403412701000_28.153.190084.17","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.200503-409OC"},{"key":"2024102403412701000_28.153.190084.18","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201103-0577OC"},{"key":"2024102403412701000_28.153.190084.19","doi-asserted-by":"crossref","first-page":"1116","DOI":"10.1097\/00003246-198712000-00008","article-title":"Effects of carbon dioxide and pH on myocardial function in dogs with acute left ventricular failure","volume":"15","author":"Wexels","year":"1987","journal-title":"Crit Care Med"},{"key":"2024102403412701000_28.153.190084.20","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1093\/oxfordjournals.bja.a013389","article-title":"Effects of respiratory and metabolic pH changes and hypoxia on ropivacaine-induced cardiotoxicity in dogs","volume":"84","author":"Porter","year":"2000","journal-title":"Br J Anaesth"},{"key":"2024102403412701000_28.153.190084.21","doi-asserted-by":"publisher","DOI":"10.1006\/jtbi.1995.0033"},{"key":"2024102403412701000_28.153.190084.22","doi-asserted-by":"crossref","unstructured":"Javed F , Tamisier R , Pepin JL , et al. 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