{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T16:09:14Z","timestamp":1785427754112,"version":"3.56.0"},"reference-count":30,"publisher":"European Respiratory Society (ERS)","issue":"167","license":[{"start":{"date-parts":[[2023,1,11]],"date-time":"2023-01-11T00:00:00Z","timestamp":1673395200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["publications.ersnet.org"],"crossmark-restriction":true},"short-container-title":["Eur Respir Rev"],"accepted":{"date-parts":[[2022,10,13]]},"published-print":{"date-parts":[[2023,3,31]]},"abstract":"<jats:p>Since 2015, the World Health Organization (WHO) has recommended prioritising testing and treatment of tuberculosis (TB) infection (TBI) in 11 high-risk groups. With new options emerging for TB preventive treatment, we conducted a scoping review, in consultation with the WHO's Global Tuberculosis Programme, to explore the evidence for other population groups at potentially high risk of progression to active TB. We searched six databases for preprints and articles published between 2000 and August 2022. 18 out of 33\u2009668 screened records were included (six meta-analyses and 12 original research studies). Most were observational studies reporting the incidence of active TB in a risk group<jats:italic>versus<\/jats:italic>control. Glomerular diseases had the strongest association with active TB (standardised incidence ratio 23.36, 95% CI 16.76\u201331.68) based on an unpublished study. Other conditions associated with increased risk of active TB included hepatitis C, malignancies, diabetes mellitus, rheumatoid arthritis and vitamin D deficiency. Corticosteroid use was also associated with increased risk in several studies, although heterogeneous definitions of exposure and indications for use challenge interpretation. Despite methodological limitations of the identified studies, expanding the recommendations for TBI screening and treatment to new risk groups such as those reported here should be considered. Further group-specific systematic reviews may provide additional data for decision-making.<\/jats:p>","DOI":"10.1183\/16000617.0127-2022","type":"journal-article","created":{"date-parts":[[2023,1,11]],"date-time":"2023-01-11T10:46:40Z","timestamp":1673434000000},"page":"220127","update-policy":"https:\/\/doi.org\/10.1183\/ers-crossmark-policy","source":"Crossref","is-referenced-by-count":10,"title":["A scoping review on the risk of tuberculosis in specific population groups: can we expand the World Health Organization recommendations?"],"prefix":"10.1183","volume":"32","author":[{"given":"Jacob","family":"Bigio","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5210-5109","authenticated-orcid":false,"given":"Angelo","family":"Viscardi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Genevieve","family":"Gore","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5109-9248","authenticated-orcid":false,"given":"Alberto","family":"Matteelli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6641-0094","authenticated-orcid":false,"given":"Giorgia","family":"Sulis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"81","published-online":{"date-parts":[[2023,1,11]]},"reference":[{"key":"2024102404091345000_32.167.220127.1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.1002152"},{"key":"2024102404091345000_32.167.220127.2","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.aje.a121593"},{"key":"2024102404091345000_32.167.220127.3","unstructured":"World Health Organization (WHO) . The End TB Strategy. 2015. www.who.int\/teams\/global-tuberculosis-programme\/the-end-tb-strategy Date last accessed: 22 June 2022."},{"key":"2024102404091345000_32.167.220127.4","doi-asserted-by":"crossref","first-page":"190","DOI":"10.5588\/ijtld.21.0753","article-title":"Clinical standards for the diagnosis, treatment and prevention of TB infection","volume":"26","author":"Migliori","year":"2022","journal-title":"Int J Tuberc Lung Dis"},{"key":"2024102404091345000_32.167.220127.5","unstructured":"World Health Organization (WHO) . WHO Consolidated Guidelines on Tuberculosis. Module 1: Prevention \u2013 Tuberculosis Preventive Treatment. 2020. https:\/\/apps.who.int\/iris\/bitstream\/handle\/10665\/331170\/9789240001503-eng.pdf Date last accessed: 22 June 2022."},{"key":"2024102404091345000_32.167.220127.6","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.01245-2015"},{"key":"2024102404091345000_32.167.220127.7","unstructured":"World Health Organization (WHO) . The End TB Strategy: Global Strategy and Targets for Tuberculosis Prevention, Care and Control after 2015. Geneva, WHO, 2014."},{"key":"2024102404091345000_32.167.220127.8","unstructured":"World Health Organization (WHO) . Latent Tuberculosis Infection: Updated and Consolidated Guidelines for Programmatic Management. 2018. https:\/\/apps.who.int\/iris\/bitstream\/handle\/10665\/260233\/9789241550239-eng.pdf?sequence=1&isAllowed=y Date last accessed: 22 June 2022."},{"key":"2024102404091345000_32.167.220127.9","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1016\/j.ijid.2022.01.063","article-title":"Effect of implementation of a 12-dose once-weekly treatment (3HP) in addition to standard regimens to prevent TB on completion rates: interrupted time series design","volume":"117","author":"Alvarez","year":"2022","journal-title":"Int J Infect Dis"},{"key":"2024102404091345000_32.167.220127.10","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1093\/jac\/dky403","article-title":"Cost-effectiveness of 3\u2009months of weekly rifapentine and isoniazid compared with other standard treatment regimens for latent tuberculosis infection: a decision analysis study","volume":"74","author":"Doan","year":"2019","journal-title":"J Antimicrob Chemother"},{"key":"2024102404091345000_32.167.220127.11","unstructured":"The Aurum Institute . IMPAACT4TB: Literature Review to Support the Public Health Case for the Scale-up of 3HP. 2018. www.impaact4tb.org\/impaact4tb-public-health-rationale-report\/"},{"key":"2024102404091345000_32.167.220127.12","doi-asserted-by":"crossref","first-page":"490","DOI":"10.1681\/ASN.20213210S1490c","article-title":"Patients with glomerular disease are at very high risk of TB infection compared to the general population","volume":"32","author":"Gunning HMC","year":"2021","journal-title":"J Am Soc Nephrol"},{"key":"2024102404091345000_32.167.220127.13","doi-asserted-by":"publisher","DOI":"10.1086\/506935"},{"key":"2024102404091345000_32.167.220127.14","doi-asserted-by":"publisher","DOI":"10.1002\/art.24476"},{"key":"2024102404091345000_32.167.220127.15","first-page":"1436","article-title":"Increased risk of tuberculosis in patients with rheumatoid arthritis","volume":"30","author":"Carmona","year":"2003","journal-title":"J Rheumatol"},{"key":"2024102404091345000_32.167.220127.16","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2012.12.966"},{"key":"2024102404091345000_32.167.220127.17","doi-asserted-by":"crossref","first-page":"1243","DOI":"10.1016\/j.jaad.2019.12.033","article-title":"Ustekinumab does not increase tuberculosis risk: results from a national database in South Korea","volume":"82","author":"Cho","year":"2020","journal-title":"J Am Acad Dermatol"},{"key":"2024102404091345000_32.167.220127.18","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1186\/s12890-017-0425-3","article-title":"Risk of incident active tuberculosis disease in patients treated with non-steroidal anti-inflammatory drugs: a population-based study","volume":"17","author":"Wu","year":"2017","journal-title":"BMC Pulm Med"},{"key":"2024102404091345000_32.167.220127.19","doi-asserted-by":"publisher","DOI":"10.5588\/ijtld.15.0031"},{"key":"2024102404091345000_32.167.220127.20","doi-asserted-by":"publisher","DOI":"10.1111\/resp.13338"},{"key":"2024102404091345000_32.167.220127.21","doi-asserted-by":"crossref","unstructured":"Baliashvili D , Blumberg HM , Benkeser D , et al . Association of treated and untreated chronic hepatitis C with the incidence of active tuberculosis disease: a population-based cohort study. Clin Infect Dis 2022; in press [https:\/\/doi.org\/10.1093\/cid\/ciac786].","DOI":"10.1093\/cid\/ciac786"},{"key":"2024102404091345000_32.167.220127.22","doi-asserted-by":"crossref","first-page":"4950","DOI":"10.21037\/jtd.2020.02.50","article-title":"Active tuberculosis risk associated with malignancies: an 18-year retrospective cohort study in Korea","volume":"12","author":"Cheon","year":"2020","journal-title":"J Thorac Dis"},{"key":"2024102404091345000_32.167.220127.23","doi-asserted-by":"crossref","first-page":"916","DOI":"10.5588\/ijtld.19.0605","article-title":"Vitamin D deficiency predicts latent TB reactivation independent of preventive therapy: a longitudinal study","volume":"24","author":"Patterson","year":"2020","journal-title":"Int J Tuberc Lung Dis"},{"key":"2024102404091345000_32.167.220127.24","doi-asserted-by":"crossref","first-page":"e0187967","DOI":"10.1371\/journal.pone.0187967","article-title":"Association between diabetes mellitus and active tuberculosis: a systematic review and meta-analysis","volume":"12","author":"Al-Rifai","year":"2017","journal-title":"PLoS One"},{"key":"2024102404091345000_32.167.220127.25","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.0050152"},{"key":"2024102404091345000_32.167.220127.26","doi-asserted-by":"crossref","first-page":"e0261246","DOI":"10.1371\/journal.pone.0261246","article-title":"Diabetes mellitus and tuberculosis, a systematic review and meta-analysis with sensitivity analysis for studies comparable for confounders","volume":"16","author":"Foe-Essomba","year":"2021","journal-title":"PLoS One"},{"key":"2024102404091345000_32.167.220127.27","doi-asserted-by":"crossref","first-page":"2219","DOI":"10.2147\/COPD.S209273","article-title":"Inhaled corticosteroids and risk of tuberculosis in patients with obstructive lung diseases: a systematic review and meta-analysis of non-randomized studies","volume":"14","author":"Castellana","year":"2019","journal-title":"Int J Chron Obstruct Pulmon Dis"},{"key":"2024102404091345000_32.167.220127.28","doi-asserted-by":"publisher","DOI":"10.1378\/chest.13-2137"},{"key":"2024102404091345000_32.167.220127.29","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.00157-2017"},{"key":"2024102404091345000_32.167.220127.30","unstructured":"National Institute for Health and Care Excellence (NICE) . Vitamin D Deficiency in Adults. 2022. https:\/\/cks.nice.org.uk\/topics\/vitamin-d-deficiency-in-adults\/ Date last accessed: 22 June 2022."}],"container-title":["European Respiratory Review"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1183\/16000617.0127-2022","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,24]],"date-time":"2025-02-24T05:05:37Z","timestamp":1740373537000},"score":1,"resource":{"primary":{"URL":"https:\/\/publications.ersnet.org\/lookup\/doi\/10.1183\/16000617.0127-2022"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,1,11]]},"references-count":30,"journal-issue":{"issue":"167","published-online":{"date-parts":[[2023,1,11]]},"published-print":{"date-parts":[[2023,3,31]]}},"alternative-id":["10.1183\/16000617.0127-2022"],"URL":"https:\/\/doi.org\/10.1183\/16000617.0127-2022","relation":{},"ISSN":["0905-9180","1600-0617"],"issn-type":[{"value":"0905-9180","type":"print"},{"value":"1600-0617","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,1,11]]}}}