{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T20:03:40Z","timestamp":1778702620784,"version":"3.51.4"},"reference-count":34,"publisher":"European Respiratory Society (ERS)","issue":"4","license":[{"start":{"date-parts":[[2022,9,16]],"date-time":"2022-09-16T00:00:00Z","timestamp":1663286400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"APHP-Fondation de France"}],"content-domain":{"domain":["publications.ersnet.org"],"crossmark-restriction":true},"short-container-title":["ERJ Open Res"],"accepted":{"date-parts":[[2022,7,24]]},"published-print":{"date-parts":[[2022,10]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>The prognosis of asthmatic outpatients with COVID-19 needs to be clarified. The objectives of this study were: 1) to investigate the characteristics and outcomes of asthmatic patients receiving initial ambulatory care and home monitoring for COVID-19 with Covidom, a telesurveillance solution; and 2) to compare the characteristics and outcomes between asthmatic and non-asthmatic patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Inclusion criteria were age \u226518\u2005years, suspected or confirmed COVID-19 diagnosis allowing initial ambulatory care, registration in Covidom between March 2020 and April 2021 and completion of the initial medical questionnaire. We compared clinical characteristics and outcomes between asthmatic and non-asthmatic patients, and we evaluated whether asthma was independently associated with clinical worsening (hospitalisation or death) within 30\u2005days follow-up using a multivariate logistic regression model.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>33\u2009815 patients met the inclusion criteria. Asthma was reported in 4276 (12.6%). The main comorbidities among asthmatic patients were obesity (23.1%), hypertension (12.7%) and diabetes (4.5%). As compared with non-asthmatic patients, asthmatic patients were more often female (70.0<jats:italic>versus<\/jats:italic>62.1%, p&lt;0.001), of younger age (42.2<jats:italic>versus<\/jats:italic>43.8\u2005years, p&lt;0.001) and obese (23.1<jats:italic>versus<\/jats:italic>17.6%, p&lt;0.001). The rate of hospitalisation did not differ significantly (4.7<jats:italic>versus<\/jats:italic>4.2%, p=0.203) and no asthmatic patient died during follow-up (<jats:italic>versus<\/jats:italic>25 non-asthmatic patients, 0.1%; p=0.109). In multivariate analysis, asthma was independently associated with higher risk of clinical worsening (OR 1.23, 95% CI 1.04\u20131.44, p=0.013).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>In a large French cohort of patients receiving initial ambulatory care and home monitoring for COVID-19, asthma was independently associated with higher risk of clinical worsening although no asthmatic patient died within the 30\u2005days follow-up.<\/jats:p><\/jats:sec>","DOI":"10.1183\/23120541.00012-2022","type":"journal-article","created":{"date-parts":[[2022,9,16]],"date-time":"2022-09-16T14:14:46Z","timestamp":1663337686000},"page":"00012-2022","update-policy":"https:\/\/doi.org\/10.1183\/ers-crossmark-policy","source":"Crossref","is-referenced-by-count":2,"title":["Characteristics and outcomes of asthmatic outpatients with COVID-19 who receive home telesurveillance"],"prefix":"10.1183","volume":"8","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0481-3266","authenticated-orcid":false,"given":"Antoine","family":"Beurnier","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Youri","family":"Yordanov","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Agn\u00e8s","family":"Dechartres","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aur\u00e9lien","family":"Dinh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erwan","family":"Debuc","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fran\u00e7ois-Xavier","family":"Lescure","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patrick","family":"Jourdain","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5815-2504","authenticated-orcid":false,"given":"Luc","family":"Jaulmes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0703-2892","authenticated-orcid":false,"given":"Marc","family":"Humbert","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"81","published-online":{"date-parts":[[2022,9,16]]},"reference":[{"key":"2024101711394641000_8.4.00012-2022.1","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1016\/S2213-2600(20)30105-3","article-title":"Prevalence and attributable health burden of chronic respiratory diseases, 1990\u20132017: a systematic analysis for the Global Burden of Disease Study 2017","volume":"8","year":"2020","journal-title":"Lancet Respir Med"},{"key":"2024101711394641000_8.4.00012-2022.2","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1136\/bmjebm-2020-111506","article-title":"Asthma and COVID-19: review of evidence on risks and management considerations","volume":"26","author":"Hartmann-Boyce","year":"2021","journal-title":"BMJ Evidence-Based Med"},{"key":"2024101711394641000_8.4.00012-2022.3","doi-asserted-by":"publisher","DOI":"10.1111\/all.14238"},{"key":"2024101711394641000_8.4.00012-2022.4","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2020.04.006"},{"key":"2024101711394641000_8.4.00012-2022.5","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.01875-2020"},{"key":"2024101711394641000_8.4.00012-2022.6","doi-asserted-by":"crossref","unstructured":"Caminati M , Vultaggio A , Matucci A , et al. Asthma in a large COVID-19 cohort: prevalence, features, and determinants of COVID-19 disease severity. Respir Med 2021; 176: 106261. doi:10.1016\/j.rmed.2020.106261","DOI":"10.1016\/j.rmed.2020.106261"},{"key":"2024101711394641000_8.4.00012-2022.7","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.02226-2020"},{"key":"2024101711394641000_8.4.00012-2022.8","doi-asserted-by":"crossref","first-page":"1027","DOI":"10.1016\/j.jaci.2020.07.026","article-title":"Asthma among hospitalised patients with COVID-19 and related outcomes","volume":"146","author":"Lovinsky-Desir","year":"2020","journal-title":"J Allergy Clin Immunol"},{"key":"2024101711394641000_8.4.00012-2022.9","doi-asserted-by":"crossref","first-page":"e20748","DOI":"10.2196\/20748","article-title":"Covidom, a telesurveillance solution for home monitoring patients with COVID-19","volume":"22","author":"Yordanov","year":"2020","journal-title":"J Med Internet Res"},{"key":"2024101711394641000_8.4.00012-2022.10","doi-asserted-by":"crossref","first-page":"1158","DOI":"10.1016\/j.cmi.2021.04.010","article-title":"Clinical characteristics and factors associated with hospital admission or death in 43\u2009103 adult outpatients with coronavirus disease 2019 managed with the Covidom telesurveillance solution: a prospective cohort study","volume":"27","author":"Yordanov","year":"2021","journal-title":"Clin Microbiol Infect"},{"key":"2024101711394641000_8.4.00012-2022.11","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.congress-2018.OA292"},{"key":"2024101711394641000_8.4.00012-2022.12","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2458-9-213"},{"key":"2024101711394641000_8.4.00012-2022.13","doi-asserted-by":"publisher","DOI":"10.1136\/thoraxjnl-2011-201249"},{"key":"2024101711394641000_8.4.00012-2022.14","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.00165109"},{"key":"2024101711394641000_8.4.00012-2022.15","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1016\/j.jaci.2020.06.010","article-title":"Prevalence and characterisation of asthma in hospitalised and nonhospitalised patients with COVID-19","volume":"146","author":"Chhiba","year":"2020","journal-title":"J Allergy Clin Immunol"},{"key":"2024101711394641000_8.4.00012-2022.16","doi-asserted-by":"publisher","DOI":"10.1503\/cmaj.081332"},{"key":"2024101711394641000_8.4.00012-2022.17","unstructured":"Global Initiative for Asthma (GINA). Global Strategy for Asthma Management and Prevention. 2021. Available from: http:\/\/ginasthma.org\/"},{"key":"2024101711394641000_8.4.00012-2022.18","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-020-77791-8"},{"key":"2024101711394641000_8.4.00012-2022.19","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-020-2521-4"},{"key":"2024101711394641000_8.4.00012-2022.20","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1016\/j.jaci.2021.06.006","article-title":"COVID-19 risk and outcomes in adult asthmatic patients treated with biologics or systemic corticosteroids: nationwide real-world evidence","volume":"148","author":"Adir","year":"2021","journal-title":"J Allergy Clin Immunol"},{"key":"2024101711394641000_8.4.00012-2022.21","doi-asserted-by":"publisher","DOI":"10.1016\/j.pcrj.2004.10.007"},{"key":"2024101711394641000_8.4.00012-2022.22","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.01578-2021"},{"key":"2024101711394641000_8.4.00012-2022.23","doi-asserted-by":"crossref","first-page":"2591","DOI":"10.3390\/jcm10122591","article-title":"Exercise ventilatory inefficiency in post-COVID-19 syndrome: insights from a prospective evaluation","volume":"10","author":"Aparisi","year":"2021","journal-title":"J Clin Med"},{"key":"2024101711394641000_8.4.00012-2022.24","doi-asserted-by":"crossref","first-page":"614590","DOI":"10.3389\/fphys.2020.614590","article-title":"Hyperventilation: a possible explanation for long-lasting exercise intolerance in mild COVID-19 survivors?","volume":"11","author":"Motiejunaite","year":"2020","journal-title":"Front Physiol"},{"key":"2024101711394641000_8.4.00012-2022.25","doi-asserted-by":"crossref","unstructured":"Taverne J , Salvator H , Leboulch C , et al. High incidence of hyperventilation syndrome after COVID-19. J Thorac Dis 2021; 13: 3918\u20133922. doi:10.21037\/jtd-20-2753","DOI":"10.21037\/jtd-20-2753"},{"key":"2024101711394641000_8.4.00012-2022.26","doi-asserted-by":"publisher","DOI":"10.1136\/thoraxjnl-2020-215314"},{"key":"2024101711394641000_8.4.00012-2022.27","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1111\/cea.13773","article-title":"The relationship between severe or dead COVID-19 and asthma: a meta-analysis","volume":"51","author":"Wang","year":"2021","journal-title":"Clin Exp Allergy"},{"key":"2024101711394641000_8.4.00012-2022.28","doi-asserted-by":"crossref","first-page":"902","DOI":"10.1111\/all.14558","article-title":"Severe asthma in adults does not significantly affect the outcome of COVID-19 disease: results from the Italian Severe Asthma Registry","volume":"76","author":"Antonicelli","year":"2021","journal-title":"Allergy"},{"key":"2024101711394641000_8.4.00012-2022.29","doi-asserted-by":"publisher","DOI":"10.1183\/16000617.0152-2021"},{"key":"2024101711394641000_8.4.00012-2022.30","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.03045-2020"},{"key":"2024101711394641000_8.4.00012-2022.31","first-page":"CD015125","article-title":"Inhaled corticosteroids for the treatment of COVID-19","volume":"3","author":"Griesel","year":"2022","journal-title":"Cochrane Database Syst Rev"},{"key":"2024101711394641000_8.4.00012-2022.32","doi-asserted-by":"crossref","first-page":"343","DOI":"10.4104\/pcrj.2009.00064","article-title":"The CYMPLA trial. Mobile phone-based structured intervention to achieve asthma control in patients with uncontrolled persistent asthma: a pragmatic randomised controlled trial","volume":"18","author":"Ryan","year":"2009","journal-title":"Prim Care Respir J J Gen Pract Airw Group"},{"key":"2024101711394641000_8.4.00012-2022.33","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1080\/02770903.2019.1709864","article-title":"Home self-monitoring in patients with asthma using a mobile spirometry system","volume":"58","author":"Kupczyk","year":"2021","journal-title":"J Asthma"},{"key":"2024101711394641000_8.4.00012-2022.34","doi-asserted-by":"crossref","first-page":"1343","DOI":"10.1513\/AnnalsATS.202005-514ST","article-title":"Restoring pulmonary and sleep services as the COVID-19 pandemic lessens. From an association of pulmonary, critical care, and sleep division directors and American Thoracic Society\u2013coordinated Task Force","volume":"17","author":"Wilson","year":"2020","journal-title":"Ann Am Thorac Soc"}],"container-title":["ERJ Open Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1183\/23120541.00012-2022","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,24]],"date-time":"2025-02-24T05:20:53Z","timestamp":1740374453000},"score":1,"resource":{"primary":{"URL":"https:\/\/publications.ersnet.org\/lookup\/doi\/10.1183\/23120541.00012-2022"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,9,16]]},"references-count":34,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2022,10,24]]},"published-print":{"date-parts":[[2022,10]]}},"alternative-id":["10.1183\/23120541.00012-2022"],"URL":"https:\/\/doi.org\/10.1183\/23120541.00012-2022","relation":{},"ISSN":["2312-0541"],"issn-type":[{"value":"2312-0541","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,9,16]]}}}