{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T12:18:12Z","timestamp":1791807492329,"version":"4.3.4"},"reference-count":25,"publisher":"European Respiratory Society (ERS)","issue":"4","content-domain":{"domain":["publications.ersnet.org"],"crossmark-restriction":true},"short-container-title":["ERJ Open Res"],"accepted":{"date-parts":[[2017,11,2]]},"published-print":{"date-parts":[[2017,10]]},"abstract":"<jats:p>This study was undertaken to investigate idiopathic pulmonary fibrosis (IPF) patients' health-related quality of life (HRQoL) and symptoms in a real-life cross-sectional study. Our secondary aim was to create a simple identification method for patients with increased need for palliative care by studying the relationship between modified Medical Research Council (mMRC) dyspnoea scale, HRQoL and symptoms.<\/jats:p>\n                  <jats:p>We sent a self-rating HRQoL questionnaire (RAND-36) and modified Edmonton Symptom Assessment Scale (ESAS) to 300 IPF patients; 84% of the patients responded to these questionnaires.<\/jats:p>\n                  <jats:p>The most prevalent (&gt;80%) symptoms were tiredness, breathlessness, cough and pain in movement. An increasing mMRC score showed a linear relationship (p&lt;0.001) to impaired HRQoL in all dimensions of RAND-36 and the severity of all symptoms in ESAS. Dimensions of RAND-36 fell below general population reference values in patients with mMRC score =2. The intensity of pain in movement (p&lt;0.001) and at rest (p=0.041), and the prevalence of chest pain (p&lt;0.001) had a positive linear relationship to increased mMRC score.<\/jats:p>\n                  <jats:p>An increasing mMRC score reflects impaired HRQoL and a high symptom burden. In clinical practice, the mMRC scale could be used for screening and identification of IPF patients with increased need for palliative care.<\/jats:p>","DOI":"10.1183\/23120541.00084-2017","type":"journal-article","created":{"date-parts":[[2017,12,15]],"date-time":"2017-12-15T20:30:24Z","timestamp":1513369824000},"page":"00084-2017","update-policy":"https:\/\/doi.org\/10.1183\/ers-crossmark-policy","source":"Crossref","is-referenced-by-count":101,"title":["mMRC dyspnoea scale indicates impaired quality of life and increased pain in patients with idiopathic pulmonary fibrosis"],"prefix":"10.1183","volume":"3","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6198-3627","authenticated-orcid":false,"given":"Kaisa","family":"Rajala","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juho T.","family":"Lehto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eva","family":"Sutinen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hannu","family":"Kautiainen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marjukka","family":"Myll\ufffdrniemi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tiina","family":"Saarto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"81","published-online":{"date-parts":[[2017,12,15]]},"reference":[{"key":"2024101706562181000_3.4.00084-2017.1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.2009-040GL"},{"key":"2024101706562181000_3.4.00084-2017.2","doi-asserted-by":"crossref","unstructured":"Kaunisto J , Kelloniemi K , Sutinen E , et al. Re-evaluation of diagnostic parameters is crucial for obtaining accurate data on idiopathic pulmonary fibrosis. BMC Pulm Med 2015; 15: 92-015-0074-3.","DOI":"10.1186\/s12890-015-0074-3"},{"key":"2024101706562181000_3.4.00084-2017.3","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1402584"},{"key":"2024101706562181000_3.4.00084-2017.4","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1402582"},{"key":"2024101706562181000_3.4.00084-2017.5","doi-asserted-by":"crossref","unstructured":"Behr J , Richeldi L . Recommendations on treatment for IPF. Respir Res 2013; 14: Suppl. 1, S6-9921-14-S1-S6.","DOI":"10.1186\/1465-9921-14-S1-S6"},{"key":"2024101706562181000_3.4.00084-2017.6","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201506-1063ST"},{"key":"2024101706562181000_3.4.00084-2017.7","doi-asserted-by":"publisher","DOI":"10.1136\/thoraxjnl-2015-207439"},{"key":"2024101706562181000_3.4.00084-2017.8","doi-asserted-by":"publisher","DOI":"10.1177\/0269216313497226"},{"key":"2024101706562181000_3.4.00084-2017.9","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0151425"},{"key":"2024101706562181000_3.4.00084-2017.10","doi-asserted-by":"publisher","DOI":"10.1016\/j.rmed.2014.01.008"},{"key":"2024101706562181000_3.4.00084-2017.11","doi-asserted-by":"publisher","DOI":"10.1016\/j.rmed.2010.02.008"},{"key":"2024101706562181000_3.4.00084-2017.12","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.200805-725OC"},{"key":"2024101706562181000_3.4.00084-2017.13","doi-asserted-by":"publisher","DOI":"10.2169\/internalmedicine.46.6218"},{"key":"2024101706562181000_3.4.00084-2017.14","doi-asserted-by":"publisher","DOI":"10.1378\/chest.117.6.1627"},{"key":"2024101706562181000_3.4.00084-2017.15","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1177\/082585979100700202","article-title":"The Edmonton Symptom Assessment System (ESAS): a simple method for the assessment of palliative care patients","volume":"7","author":"Bruera","year":"1991","journal-title":"J Palliat Care"},{"key":"2024101706562181000_3.4.00084-2017.16","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0142(20000501)88:9<2164::AID-CNCR24>3.0.CO;2-5"},{"key":"2024101706562181000_3.4.00084-2017.17","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpainsymman.2014.10.013"},{"key":"2024101706562181000_3.4.00084-2017.18","doi-asserted-by":"publisher","DOI":"10.1378\/chest.93.3.580"},{"key":"2024101706562181000_3.4.00084-2017.19","doi-asserted-by":"publisher","DOI":"10.1136\/thx.54.7.581"},{"key":"2024101706562181000_3.4.00084-2017.20","doi-asserted-by":"publisher","DOI":"10.3109\/07853890109002089"},{"key":"2024101706562181000_3.4.00084-2017.21","first-page":"1","article-title":"RAND-36 terveyteen liittyv\ufffdn el\ufffdm\ufffdnlaadun mittarina : Mittarin luotettavuus ja suomalaiset v\ufffdest\ufffdarvot [RAND-36 health-related quality of life: meter reliability and Finnish population values]","volume":"101","author":"Aalto","year":"1999","journal-title":"Tutkimuksia\/Sosiaali- ja terveysalan tutkimus- ja kehitt\ufffdmiskeskus"},{"key":"2024101706562181000_3.4.00084-2017.22","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1007\/s00408-016-9850-y","article-title":"Health-related quality of life in patients with idiopathic pulmonary fibrosis","volume":"194","author":"Yount","year":"2016","journal-title":"Lung"},{"key":"2024101706562181000_3.4.00084-2017.23","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.00152609"},{"key":"2024101706562181000_3.4.00084-2017.24","doi-asserted-by":"crossref","unstructured":"Janssen DJ , Wouters EF , Parra YL , et al. Prevalence of thoracic pain in patients with chronic obstructive pulmonary disease and relationship with patient characteristics: A cross-sectional observational study. BMC Pulm Med 2016; 16: 47-016-0210-8.","DOI":"10.1186\/s12890-016-0210-8"},{"key":"2024101706562181000_3.4.00084-2017.25","doi-asserted-by":"publisher","DOI":"10.1016\/0007-0971(76)90030-9"}],"container-title":["ERJ Open Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1183\/23120541.00084-2017","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,23]],"date-time":"2025-02-23T23:55:15Z","timestamp":1740354915000},"score":1,"resource":{"primary":{"URL":"https:\/\/publications.ersnet.org\/lookup\/doi\/10.1183\/23120541.00084-2017"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,10]]},"references-count":25,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2017,12,15]]},"published-print":{"date-parts":[[2017,10]]}},"alternative-id":["10.1183\/23120541.00084-2017"],"URL":"https:\/\/doi.org\/10.1183\/23120541.00084-2017","relation":{},"ISSN":["2312-0541"],"issn-type":[{"value":"2312-0541","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,10]]}}}