{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,19]],"date-time":"2026-05-19T10:10:46Z","timestamp":1779185446038,"version":"3.51.4"},"reference-count":20,"publisher":"European Respiratory Society (ERS)","issue":"2","license":[{"start":{"date-parts":[[2025,11,9]],"date-time":"2025-11-09T00:00:00Z","timestamp":1762646400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000056","name":"National Institute of Nursing Research","doi-asserted-by":"publisher","award":["NR010006"],"award-info":[{"award-number":["NR010006"]}],"id":[{"id":"10.13039\/100000056","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["publications.ersnet.org"],"crossmark-restriction":true},"short-container-title":["ERJ Open Res"],"accepted":{"date-parts":[[2025,8,27]]},"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Patients can report respiratory discomfort (dyspnoea) on a 0\u201310 scale. Patients reporting dyspnoea at admission have a four-fold risk of in-hospital death. We asked whether assessing dyspnoea throughout hospitalisation identifies additional patients at risk of death or other poor outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We conducted a retrospective cohort study of non-intensive care unit patients at a tertiary care hospital. On each shift, bedside nurses documented patients\u2019 pain and dyspnoea ratings. We tested associations with inpatient mortality, 2-year mortality and other outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      We evaluated 9785 admissions; 18% of patients reported dyspnoea at admission and 10% developed post-admission dyspnoea. Patients with post-admission-onset dyspnoea had six-fold greater odds of death during hospitalisation (OR 6.0, 95% CI 4.2\u20138.5, p&lt;0.0001)\n                      <jats:italic>versus<\/jats:italic>\n                      patients without dyspnoea. Compared with those without dyspnoea, patients with dyspnoea had 50% greater mortality during the following 2\u2005years, and those with dyspnoea on the day of discharge had even greater mortality (HR 2.6, 95% CI 2.1\u20133.2, p&lt;0.0001). Higher patient dyspnoea ratings predicted higher in-hospital and 2-year mortality. Pain (reported by 72% of patients) was not significantly associated with mortality. Dyspnoea was also related to greater length of stay, rapid response team activation, transfer to the intensive care unit and discharge to extended care.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>In contrast to pain, both admission dyspnoea and post-admission-onset dyspnoea were associated with substantially increased odds of poor patient outcomes during hospitalisation and following discharge. Documenting dyspnoea throughout hospitalisation provides a powerful alarm of clinical compromise that may warrant additional attention and outpatient follow-up.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1183\/23120541.00804-2025","type":"journal-article","created":{"date-parts":[[2025,11,10]],"date-time":"2025-11-10T02:15:14Z","timestamp":1762740914000},"page":"00804-2025","update-policy":"https:\/\/doi.org\/10.1183\/ers-crossmark-policy","source":"Crossref","is-referenced-by-count":1,"title":["Patient-reported dyspnoea predicts six-fold increased hospital mortality"],"prefix":"10.1183","volume":"12","author":[{"given":"Jennifer P.","family":"Stevens","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Richard M.","family":"Schwartzstein","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrew R.","family":"Sheridan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carl R.","family":"O'Donnell","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kathy M.","family":"Baker","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3626-5735","authenticated-orcid":false,"given":"Robert B.","family":"Banzett","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"81","published-online":{"date-parts":[[2025,11,9]]},"reference":[{"key":"2026050510151376000_12.2.00804-2025.1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201111-2042ST"},{"key":"2026050510151376000_12.2.00804-2025.2","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.02099-2016"},{"key":"2026050510151376000_12.2.00804-2025.3","doi-asserted-by":"publisher","DOI":"10.1136\/bmjresp-2019-000493"},{"key":"2026050510151376000_12.2.00804-2025.4","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa042741"},{"key":"2026050510151376000_12.2.00804-2025.5","doi-asserted-by":"publisher","DOI":"10.1378\/chest.121.5.1434"},{"key":"2026050510151376000_12.2.00804-2025.6","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.jpainsymman.2018.02.013","article-title":"Prevalence of dyspnea among hospitalized patients at the time of admission","volume":"56","author":"Stevens","year":"2018","journal-title":"J Pain Symptom Manage"},{"key":"2026050510151376000_12.2.00804-2025.7","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.02107-2019"},{"key":"2026050510151376000_12.2.00804-2025.8","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.00988-2021"},{"key":"2026050510151376000_12.2.00804-2025.9","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1186\/s12912-016-0196-9","article-title":"Routine dyspnea assessment and documentation: nurses\u2019 experience yields wide acceptance","volume":"16","author":"Baker","year":"2017","journal-title":"BMC Nurs"},{"key":"2026050510151376000_12.2.00804-2025.10","doi-asserted-by":"crossref","first-page":"e0152601","DOI":"10.1371\/journal.pone.0152601","article-title":"Prevalence and predictive value of dyspnea ratings in hospitalized patients: pilot studies","volume":"11","author":"Stevens","year":"2016","journal-title":"PLoS ONE"},{"key":"2026050510151376000_12.2.00804-2025.11","doi-asserted-by":"publisher","DOI":"10.1080\/03007995.2017.1297702"},{"key":"2026050510151376000_12.2.00804-2025.12","doi-asserted-by":"publisher","DOI":"10.1111\/crj.12191"},{"key":"2026050510151376000_12.2.00804-2025.13","doi-asserted-by":"publisher","DOI":"10.1093\/occmed\/kqm162"},{"key":"2026050510151376000_12.2.00804-2025.14","doi-asserted-by":"crossref","first-page":"e0165111","DOI":"10.1371\/journal.pone.0165111","article-title":"Prognostic importance of dyspnea for cardiovascular outcomes and mortality in persons without prevalent cardiopulmonary disease: the atherosclerosis risk in communities study","volume":"11","author":"Santos","year":"2016","journal-title":"PLoS ONE"},{"key":"2026050510151376000_12.2.00804-2025.15","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1186\/s13049-016-0204-9","article-title":"Dyspnea, a high-risk symptom in patients suspected of myocardial infarction in the ambulance? 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