{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,11]],"date-time":"2026-05-11T11:17:35Z","timestamp":1778498255165,"version":"3.51.4"},"reference-count":21,"publisher":"European Respiratory Society (ERS)","issue":"3","license":[{"start":{"date-parts":[[2025,12,11]],"date-time":"2025-12-11T00:00:00Z","timestamp":1765411200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["publications.ersnet.org"],"crossmark-restriction":true},"short-container-title":["ERJ Open Res"],"accepted":{"date-parts":[[2025,11,20]]},"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Solitary fibrous tumours of the pleura (SFTP) are rare neoplasms for which surgical resection is considered the gold standard treatment. Anecdotally, SFTPs are sometimes conservatively managed, but there are little data on this in published literature. In this study, we aimed to collect data on radiological features in SFTP which might be associated with a benign clinical course to assist in risk stratification, and therefore selection for a more conservative management pathway.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      A service evaluation of outcomes of radiologically diagnosed SFTP was completed in 12 UK centres, between 2005 and 2015. Cases were included\n                      <jats:italic>via<\/jats:italic>\n                      initial search of local radiology databases using key words (\u201cPleural fibroma\u201d OR \u201cfibrous tumour of the pleura\u201d OR \u201cSFTP\u201d). Baseline characteristics and outcome data were obtained from medical records.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 270 patients were included in the study. Factors associated with the need for surgical intervention included lesion size (&gt;128\u2005mm), lesion position (abutting the mediastinum or diaphragm), associated pleural effusion, radiological evidence of necrosis within the lesion and heterogeneous density. In multivariate analysis, computed tomography-measured attenuation and homogeneous density were independent risk factors for adverse clinical outcomes in patients with resected fibromas.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This is the largest study to date on SFTP to include conservatively managed cases who underwent radiological follow-up only. The results suggest several features associated with adverse clinical outcomes, and thereby may identify cases which could be more conservatively (observation only) managed. Further prospective studies are required to assess the identified risk factors as part of a potential radiological scoring system.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1183\/23120541.01018-2025","type":"journal-article","created":{"date-parts":[[2025,12,11]],"date-time":"2025-12-11T18:50:25Z","timestamp":1765479025000},"page":"01018-2025","update-policy":"https:\/\/doi.org\/10.1183\/ers-crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Outcomes of radiologically diagnosed solitary fibrous tumours of the pleura"],"prefix":"10.1183","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8038-5822","authenticated-orcid":false,"given":"Mohamed","family":"Ellayeh","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rachel","family":"Mercer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1180-5325","authenticated-orcid":false,"given":"Sayed","family":"Alqarooni","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zainab","family":"Sharaf","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Graham","family":"Dack","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Shatti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3158-7740","authenticated-orcid":false,"given":"David","family":"Arnold","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lucia","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7751-0111","authenticated-orcid":false,"given":"Gordon W.","family":"Cowell","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alison","family":"Stockbridge","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0859-5550","authenticated-orcid":false,"given":"Avinash","family":"Aujayeb","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Louise","family":"Wing","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rachel","family":"Benamore","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Najib M.","family":"Rahman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"81","published-online":{"date-parts":[[2025,12,11]]},"reference":[{"key":"2026051103401199000_12.3.01018-2025.1","doi-asserted-by":"crossref","first-page":"3865","DOI":"10.1245\/s10434-017-6092-z","article-title":"Size and location are the most important risk factors for malignant behavior in resected solitary fibrous tumors","volume":"24","author":"Gholami","year":"2017","journal-title":"Ann Surg Oncol"},{"key":"2026051103401199000_12.3.01018-2025.2","doi-asserted-by":"crossref","first-page":"796.e9","DOI":"10.1016\/j.crad.2017.03.028","article-title":"Solitary fibrous tumour of pleura: CT differentiation of benign and malignant types","volume":"72","author":"Gupta","year":"2017","journal-title":"Clin Radiol"},{"key":"2026051103401199000_12.3.01018-2025.3","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.11.8430"},{"key":"2026051103401199000_12.3.01018-2025.4","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1016\/j.rcl.2015.12.006","article-title":"Solitary fibrous tumors: 2016 imaging update","volume":"54","author":"Keraliya","year":"2016","journal-title":"Radiol Clin North Am"},{"key":"2026051103401199000_12.3.01018-2025.5","doi-asserted-by":"publisher","DOI":"10.1183\/23120541.00055-2020"},{"key":"2026051103401199000_12.3.01018-2025.6","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-198908000-00003"},{"key":"2026051103401199000_12.3.01018-2025.7","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1016\/j.athoracsur.2012.04.028","article-title":"Solitary fibrous tumor of the pleura: outcomes of 157 complete resections in a single center","volume":"94","author":"Lahon","year":"2012","journal-title":"Ann Thorac Surg"},{"key":"2026051103401199000_12.3.01018-2025.8","doi-asserted-by":"publisher","DOI":"10.1038\/modpathol.2012.83"},{"key":"2026051103401199000_12.3.01018-2025.9","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdx250"},{"key":"2026051103401199000_12.3.01018-2025.10","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1016\/j.diii.2015.04.013","article-title":"Solitary fibrous tumor of the pleura: can computed tomography features help predict malignancy? 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