{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T19:55:16Z","timestamp":1791921316255,"version":"4.3.4"},"reference-count":26,"publisher":"European Respiratory Society (ERS)","issue":"2","license":[{"start":{"date-parts":[[2025,12,11]],"date-time":"2025-12-11T00:00:00Z","timestamp":1765411200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["GNT1170958"],"award-info":[{"award-number":["GNT1170958"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["GNT2025379"],"award-info":[{"award-number":["GNT2025379"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["GNT2034451"],"award-info":[{"award-number":["GNT2034451"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["MRF2024916"],"award-info":[{"award-number":["MRF2024916"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["publications.ersnet.org"],"crossmark-restriction":true},"short-container-title":["ERJ Open Res"],"accepted":{"date-parts":[[2025,9,28]]},"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Achieving good asthma control is a goal of asthma management. In children, asthma control and quality-of-life assessments include determining the presence of wheeze. However, wheeze is unreliably reported with high disagreement (&gt;50%) between parental and physician detection of wheeze. Objectively defining wheeze using WheezeScan\u2122 (a user-friendly, artificial intelligence-based device) could improve assessment of asthma control and hence management.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Our primary aim is to determine whether adding WheezeScan\u2122 to routine clinical care improves parental asthma control assessment (ACA) in children (aged 4\u201311\u2005years). Our secondary aims are to examine the impact of WheezeScan\u2122 upon patient-reported outcomes (PROs), the parent asthma management self-efficacy scale (PAMS), healthcare costs and ease of WheezeScan\u2122 use. The primary hypothesis is that using WheezeScan\u2122 alters the ACA group.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Our multicentre prospective cohort study involves 125 children with specialist-confirmed asthma. Over 5\u2005weeks, parents\/caregivers use the WheezeScan\u2122 twice-daily at home and whenever wheezing is suspected. After the first week of using the WheezeScan\u2122, asthma medications may be adjusted based upon the child's asthma control score and WheezeScan\u2122 data. Study outcomes are collected at baseline, week\u20051 and week\u20055. Our primary end-point is the proportion of children whose assessment of asthma control changed between week\u20051 and baseline, based upon parental assessments using WheezeScan\u2122 data. Secondary outcomes are PROs (asthma-related quality of life), PAMS, healthcare costs and WheezeScan\u2122 ease of use.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>This protocol describes our study to determine whether using digital technology to accurately identify wheeze in children with asthma improves their asthma assessment and asthma-related PROs, including PAMS and healthcare costs.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1183\/23120541.01217-2025","type":"journal-article","created":{"date-parts":[[2025,12,11]],"date-time":"2025-12-11T18:50:26Z","timestamp":1765479026000},"page":"01217-2025","update-policy":"https:\/\/doi.org\/10.1183\/ers-crossmark-policy","source":"Crossref","is-referenced-by-count":1,"title":["Improving asthma control assessment and outcomes in children with asthma using an artificial intelligence digital tool: a prospective multicentre cohort study"],"prefix":"10.1183","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1331-3706","authenticated-orcid":false,"given":"Anne B.","family":"Chang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephanie T.","family":"Yerkovich","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven M.","family":"McPhail","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiran","family":"Selvadurai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vikas","family":"Goyal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shane","family":"George","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0210-1468","authenticated-orcid":false,"given":"Gabrielle B.","family":"McCallum","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter S.","family":"Morris","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hannah","family":"O'Farrell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lesley A.","family":"Versteegh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3109-6028","authenticated-orcid":false,"given":"Jonathan","family":"Grigg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Margaret S.","family":"McElrea","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sophie","family":"Worley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leanne","family":"Elliot-Holmes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Terase","family":"Yerkovich","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joanna","family":"Williams","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keith","family":"Grimwood","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julie M.","family":"Marchant","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"81","published-online":{"date-parts":[[2025,12,11]]},"reference":[{"key":"2026050510153144000_12.2.01217-2025.1","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1016\/S2213-2600(24)00383-7","article-title":"Asthma: epidemiology, risk factors, and opportunities for prevention and treatment","volume":"13","author":"Jayasooriya","year":"2025","journal-title":"Lancet Respir Med"},{"key":"2026050510153144000_12.2.01217-2025.2","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1002\/ped4.12165","article-title":"Airway function throughout the lifespan: pediatric origins of adult respiratory disease","volume":"3","author":"Allen","year":"2019","journal-title":"Pediatr Investig"},{"key":"2026050510153144000_12.2.01217-2025.3","doi-asserted-by":"publisher","DOI":"10.1183\/16000617.0044-2025"},{"key":"2026050510153144000_12.2.01217-2025.4","unstructured":"Global Initiative for Asthma. 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