{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,11]],"date-time":"2026-11-11T15:27:43Z","timestamp":1794410863970,"version":"4.9.0"},"reference-count":38,"publisher":"European Respiratory Society (ERS)","issue":"4","license":[{"start":{"date-parts":[[2025,2,6]],"date-time":"2025-02-06T00:00:00Z","timestamp":1738800000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100004325","name":"AstraZeneca","doi-asserted-by":"publisher","award":["N\/A"],"award-info":[{"award-number":["N\/A"]}],"id":[{"id":"10.13039\/100004325","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["publications.ersnet.org"],"crossmark-restriction":true},"short-container-title":["ERJ Open Res"],"accepted":{"date-parts":[[2025,1,3]]},"published-print":{"date-parts":[[2025,7]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>To assess health status in respiratory diseases, the Chronic Airways Assessment Test (CAAT) was adapted from the COPD Assessment Test (CAT) by replacing COPD-specific wording. It has demonstrated good psychometric properties in asthma and\/or COPD. This cross-sectional analysis evaluated how CAAT scores are associated with clinical characteristics in patients with asthma and\/or COPD.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      Using baseline NOVELTY data (\n                      <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"clintrialgov\" xlink:href=\"NCT02760329\">NCT02760329<\/jats:ext-link>\n                      ) for patients with physician-assigned asthma and\/or COPD, linear regression models were implemented to assess the association between CAAT score (range 0\u201340; higher scores indicating worse health status) and physician-assessed severity, lung function, modified Medical Research Council dyspnoea grade, Respiratory Symptoms Questionnaire score and, for asthma and asthma+COPD, symptom control assessed by Asthma Control Test score.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Among 7828 patients (asthma: 4138; asthma+COPD: 991; COPD: 2699), CAAT score was lower in patients with asthma (mean\u00b1\n                      <jats:sc>sd<\/jats:sc>\n                      14.0\u00b18.5)\n                      <jats:italic>versus<\/jats:italic>\n                      patients with asthma+COPD (17.2\u00b18.6) or COPD (17.0\u00b18.3), indicating better health status in asthma. Associations between CAAT score and clinical characteristics were similar across diagnostic groups (interaction p-values &gt;0.01), with higher CAAT scores associated with more respiratory symptoms, greater exercise limitation due to breathlessness, lower lung function, worse physician-assessed severity and (in asthma+COPD) with worse asthma symptom control. CAAT scores among those with asthma were lower\n                      <jats:italic>versus<\/jats:italic>\n                      other diagnostic groups by physician-assessed severities. Findings were similar when adjusting for age and for age, sex and smoking status.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The CAAT demonstrated consistent cross-sectional validity across asthma and\/or COPD, making it applicable for assessing health status in these conditions in clinical practice and research.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1183\/23120541.01359-2024","type":"journal-article","created":{"date-parts":[[2025,2,6]],"date-time":"2025-02-06T13:10:39Z","timestamp":1738847439000},"page":"01359-2024","update-policy":"https:\/\/doi.org\/10.1183\/ers-crossmark-policy","source":"Crossref","is-referenced-by-count":11,"title":["Validity of the Chronic Airways Assessment Test (CAAT) in asthma, asthma+COPD and COPD in NOVELTY"],"prefix":"10.1183","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6087-9182","authenticated-orcid":false,"given":"Paul W.","family":"Jones","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erin L.","family":"Tomaszewski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Belton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0903-9828","authenticated-orcid":false,"given":"Pierre-R\u00e9gis","family":"Burgel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rod","family":"Hughes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christina","family":"Keen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4349-8745","authenticated-orcid":false,"given":"Barry J.","family":"Make","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6924-4500","authenticated-orcid":false,"given":"Alberto","family":"Papi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hana","family":"M\u00fcllerov\u00e1","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6695-6350","authenticated-orcid":false,"given":"Helen K.","family":"Reddel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"for the NOVELTY Scientific Community and the NOVELTY study investigators","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"81","published-online":{"date-parts":[[2025,2,6]]},"reference":[{"key":"2025072103300624000_11.4.01359-2024.1","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1038\/s41533-019-0149-3","article-title":"A systematic review of psychological, physical health factors, and quality of life in adult asthma","volume":"29","author":"Stanescu","year":"2019","journal-title":"NPJ Prim Care Respir Med"},{"key":"2025072103300624000_11.4.01359-2024.2","doi-asserted-by":"crossref","first-page":"905","DOI":"10.2147\/COPD.S192280","article-title":"To live a life with COPD \u2013 the consequences of symptom burden","volume":"14","author":"Johansson","year":"2019","journal-title":"Int J Chron Obstruct Pulmon Dis"},{"key":"2025072103300624000_11.4.01359-2024.3","unstructured":"Global Initiative for Chronic Obstructive Lung Disease . 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