{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,3,25]],"date-time":"2025-03-25T04:06:39Z","timestamp":1742875599207,"version":"3.40.2"},"reference-count":43,"publisher":"European Respiratory Society (ERS)","issue":"2","license":[{"start":{"date-parts":[[2024,10,31]],"date-time":"2024-10-31T00:00:00Z","timestamp":1730332800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"Programa Operacional Competitividade e Internacionaliza\u00e7\u00e3o","award":["COMPETE 2020 - POCI-01-0145-FEDER-007628; UIDB\/045"],"award-info":[{"award-number":["COMPETE 2020 - POCI-01-0145-FEDER-007628; UIDB\/045"]}]},{"name":"Programa Operacional Inclus\u00e3o Social e Emprego","award":["POISE-03-4639-FSE-000597"],"award-info":[{"award-number":["POISE-03-4639-FSE-000597"]}]},{"DOI":"10.13039\/501100001871","name":"Funda\u00e7\u00e3o para a Ci\u00eancia e a Tecnologia","doi-asserted-by":"publisher","award":["2023.01387.BDANA","COVID\/BD\/153477\/2023","SFRH\/BD\/148741\/2019"],"award-info":[{"award-number":["2023.01387.BDANA","COVID\/BD\/153477\/2023","SFRH\/BD\/148741\/2019"]}],"id":[{"id":"10.13039\/501100001871","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100008530","name":"European Regional Development Fund","doi-asserted-by":"publisher","award":["POCI-01-0145-FEDER- 007628","SAICT-POL\/23926\/2016"],"award-info":[{"award-number":["POCI-01-0145-FEDER- 007628","SAICT-POL\/23926\/2016"]}],"id":[{"id":"10.13039\/501100008530","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100020794","name":"Institute of Biomedicine, University of Aveiro","doi-asserted-by":"publisher","award":["UIDB\/04501\/2020"],"award-info":[{"award-number":["UIDB\/04501\/2020"]}],"id":[{"id":"10.13039\/100020794","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["publications.ersnet.org"],"crossmark-restriction":true},"short-container-title":["ERJ Open Res"],"accepted":{"date-parts":[[2024,9,4]]},"published-print":{"date-parts":[[2025,3]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Pulmonary rehabilitation (PR) is essential for people with chronic respiratory diseases (CRDs), yet its impact on cough-related quality of life (CR-QoL) remains unexplored. We assessed the effects of PR on CR-QoL, described the characteristics of responders and nonresponders to PR, and explored determinants of responsiveness in this health domain in individuals with CRDs.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A retrospective study was conducted. We assessed CR-QoL using the Leicester Cough Questionnaire (LCQ) and the impact of the disease with the COPD Assessment Test (CAT), before and after PR. Cut-offs of &lt;17.05 in LCQ total score and \u226510 in CAT were used to detect low CR-QoL and medium impact of the disease. Responders were defined as achieving a minimal clinically important difference (MCID) of \u22651.3 on the LCQ total score. Pre-<jats:italic>versus<\/jats:italic>post-PR analysis involved the t-test, Wilcoxon test or McNemar test and comparisons between groups included the independent t-test, Mann\u2013Whitney U-test or Fisher's exact test. Logistic regression was employed to investigate factors influencing MCID achievement.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>135 participants with CRDs (39% females; age 68\u00b110\u2005years; 61% COPD; forced expiratory volume in 1\u2005s (FEV<jats:sub>1<\/jats:sub>) % pred 62.6\u00b123.0%) were included. After PR, significant improvements were observed in all LCQ domains and CAT. 31% of participants were identified as responders in the LCQ (36% females; age 66\u00b110\u2005years; 62% COPD; FEV<jats:sub>1<\/jats:sub>% pred 60.0\u00b122.3%), showcasing significant differences in the LCQ and CAT compared to nonresponders. People with low CR-QoL and medium\/high impact of the disease at baseline were 11 and 4 times more likely to respond to PR in CR-QoL, respectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>PR enhances CR-QoL. Identification of CR-QoL and disease impact traits at baseline offers insights to optimise this outcome responsiveness to PR.<\/jats:p><\/jats:sec>","DOI":"10.1183\/23120541.00308-2024","type":"journal-article","created":{"date-parts":[[2024,10,31]],"date-time":"2024-10-31T17:15:18Z","timestamp":1730394918000},"page":"00308-2024","update-policy":"https:\/\/doi.org\/10.1183\/ers-crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Cough in pulmonary rehabilitation: a retrospective analysis of responders and nonresponders"],"prefix":"10.1183","volume":"11","author":[{"given":"Ana 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