{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T07:14:52Z","timestamp":1791616492608,"version":"4.3.4"},"reference-count":52,"publisher":"Informa UK Limited","issue":"10","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Current Medical Research and Opinion"],"published-print":{"date-parts":[[2007,10]]},"DOI":"10.1185\/030079907x226302","type":"journal-article","created":{"date-parts":[[2007,8,28]],"date-time":"2007-08-28T00:43:51Z","timestamp":1188261831000},"page":"2441-2452","source":"Crossref","is-referenced-by-count":93,"title":["Azelastine hydrochloride:a review of pharmacology, pharmacokinetics, clinical efficacy and tolerability"],"prefix":"10.1185","volume":"23","author":[{"given":"Jonathan A.","family":"Bernstein","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2007,8,24]]},"reference":[{"key":"CIT0001","doi-asserted-by":"publisher","DOI":"10.1016\/S1081-1206(10)63155-9"},{"key":"CIT0002","first-page":"345","volume":"22","author":"Reed SD","year":"2004","journal-title":"McCrory DC. The economic burden of allergic rhinitis: a critical evaluation of the literature. Pharmacoeconomics"},{"key":"CIT0003","doi-asserted-by":"publisher","DOI":"10.1016\/S0091-6749(99)70463-X"},{"key":"CIT0004","first-page":"185","volume":"22","author":"Settipane RA","year":"2001","journal-title":"Allergy Asthma Proc"},{"key":"CIT0005","doi-asserted-by":"publisher","DOI":"10.1016\/S1081-1206(10)62543-4"},{"key":"CIT0006","doi-asserted-by":"publisher","DOI":"10.1067\/mai.2001.118891"},{"key":"CIT0008","first-page":"611","volume":"21","author":"Lieberman P","year":"2005","journal-title":"Open-label evaluation of azelastine nasal spray in patients with seasonal allergic rhinitis and nonallergic vasomotor rhinitis. Curr Med Res Opin"},{"key":"CIT0009","doi-asserted-by":"publisher","DOI":"10.1016\/0091-6749(93)90171-B"},{"key":"CIT0010","doi-asserted-by":"publisher","DOI":"10.1067\/mai.2001.115569"},{"key":"CIT0012","doi-asserted-by":"publisher","DOI":"10.1097\/01.moo.0000122310.13359.79"},{"key":"CIT0014","doi-asserted-by":"publisher","DOI":"10.1016\/S1081-1206(10)62352-6"},{"key":"CIT0016","doi-asserted-by":"publisher","DOI":"10.1016\/S1081-1206(10)63546-6"},{"key":"CIT0024","doi-asserted-by":"publisher","DOI":"10.2500\/ajr.2007.21.3058"},{"key":"CIT0025","first-page":"258","volume":"91","author":"Pearlman D","year":"2003","journal-title":"Histamine skin test reactivity following single and multiple doses of azelastine nasal spray in patients with seasonal allergic rhinitis. Ann Allergy Asthma Immunol"},{"key":"CIT0028","first-page":"1184","volume":"31","author":"Zechel HJ","year":"1981","journal-title":"Pharmacological and toxicological properties of azelastine, a novel anti-allergic agent. Arzneim-Forsch"},{"key":"CIT0030","doi-asserted-by":"publisher","DOI":"10.1016\/0091-6749(89)90013-4"},{"key":"CIT0031","first-page":"1196","volume":"31","author":"Katayama S","year":"1981","journal-title":"Arzneim-Forsch"},{"key":"CIT0032","doi-asserted-by":"publisher","DOI":"10.1016\/S1081-1206(10)63289-9"},{"key":"CIT0033","doi-asserted-by":"publisher","DOI":"10.1111\/j.1398-9995.1997.tb04878.x"},{"key":"CIT0034","doi-asserted-by":"publisher","DOI":"10.1159\/000234309"},{"key":"CIT0035","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2222.1992.tb03085.x"},{"key":"CIT0036","first-page":"206","volume":"9","author":"Matsumura M","year":"1990","journal-title":"Respir Res"},{"key":"CIT0037","doi-asserted-by":"publisher","DOI":"10.1016\/S1081-1206(10)63465-5"},{"key":"CIT0038","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2222.1993.tb02486.x"},{"key":"CIT0039","doi-asserted-by":"crossref","first-page":"2932","DOI":"10.4049\/jimmunol.159.6.2932","volume":"159","author":"Hide I","year":"1997","journal-title":"J Immunol"},{"key":"CIT0040","first-page":"481","volume":"12","author":"Matsuo S","year":"1998","journal-title":"In Vivo"},{"key":"CIT0041","doi-asserted-by":"publisher","DOI":"10.1254\/jjp.73.145"},{"key":"CIT0042","first-page":"1143","volume":"48","author":"Ito H","year":"1998","journal-title":"Arzneim-Forsch"},{"key":"CIT0044","doi-asserted-by":"publisher","DOI":"10.1016\/S0091-6749(96)80196-5"},{"key":"CIT0045","doi-asserted-by":"publisher","DOI":"10.1016\/S1081-1206(10)61829-7"},{"key":"CIT0046","doi-asserted-by":"publisher","DOI":"10.1016\/0091-6749(89)90125-5"},{"key":"CIT0047","doi-asserted-by":"publisher","DOI":"10.1016\/0006-2952(92)90619-T"},{"key":"CIT0048","doi-asserted-by":"publisher","DOI":"10.1185\/03007999309111546"},{"key":"CIT0049","doi-asserted-by":"publisher","DOI":"10.1016\/0014-2999(88)90451-7"},{"key":"CIT0050","doi-asserted-by":"publisher","DOI":"10.1002\/j.1552-4604.1997.tb04289.x"},{"key":"CIT0051","first-page":"91","volume":"76","author":"Sale M","year":"1996","journal-title":"Ann Allergy Asthma Immunol"},{"key":"CIT0052","doi-asserted-by":"publisher","DOI":"10.1016\/0091-6749(94)90115-5"},{"key":"CIT0053","first-page":"354","volume":"72","author":"Meltzer EO","year":"1994","journal-title":"Ann Allergy"},{"key":"CIT0054","doi-asserted-by":"publisher","DOI":"10.1016\/0091-6749(94)90148-1"},{"key":"CIT0055","first-page":"382","volume":"73","author":"Storms WW","year":"1994","journal-title":"ENT J"},{"key":"CIT0056","doi-asserted-by":"publisher","DOI":"10.1016\/S1081-1206(10)63420-5"},{"key":"CIT0058","first-page":"205","volume":"91","author":"Berger WE","year":"2003","journal-title":"Efficacy of azelastine nasal spray in patients with an unsatisfactory response to loratadine. Ann Allergy Asthma Immunol"},{"key":"CIT0059","doi-asserted-by":"publisher","DOI":"10.1016\/S1081-1206(10)61468-8"},{"key":"CIT0060","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinthera.2005.04.012"},{"key":"CIT0061","doi-asserted-by":"publisher","DOI":"10.1016\/S1081-1206(10)60804-6"},{"key":"CIT0062","doi-asserted-by":"publisher","DOI":"10.1378\/chest.106.5.1487"},{"key":"CIT0063","first-page":"1189","volume":"110","author":"Tomooka LT","year":"2000","journal-title":"Clinical study and literature review of nasal irrigation. Laryngoscope"},{"key":"CIT0064","doi-asserted-by":"publisher","DOI":"10.1016\/S0091-6749(99)70380-5"},{"key":"CIT0067","doi-asserted-by":"publisher","DOI":"10.1016\/S0091-6749(95)70220-2"},{"key":"CIT0069","doi-asserted-by":"publisher","DOI":"10.1007\/BF03256639"},{"key":"CIT0071","doi-asserted-by":"publisher","DOI":"10.1016\/S0091-6749(97)70046-0"},{"key":"CIT0072","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2222.1996.tb00653.x"}],"container-title":["Current Medical Research and Opinion"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.tandfonline.com\/doi\/pdf\/10.1185\/030079907X226302","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,13]],"date-time":"2023-05-13T22:54:55Z","timestamp":1684018495000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.tandfonline.com\/doi\/full\/10.1185\/030079907X226302"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,8,24]]},"references-count":52,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2007,8,13]]},"published-print":{"date-parts":[[2007,10]]}},"alternative-id":["10.1185\/030079907X226302"],"URL":"https:\/\/doi.org\/10.1185\/030079907x226302","relation":{},"ISSN":["0300-7995","1473-4877"],"issn-type":[{"value":"0300-7995","type":"print"},{"value":"1473-4877","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,8,24]]}}}