{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T06:37:42Z","timestamp":1791873462666,"version":"4.3.4"},"reference-count":38,"publisher":"Informa UK Limited","issue":"10","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Current Medical Research and Opinion"],"published-print":{"date-parts":[[2007,10]]},"DOI":"10.1185\/030079907x233098","type":"journal-article","created":{"date-parts":[[2007,9,17]],"date-time":"2007-09-17T21:00:06Z","timestamp":1190062806000},"page":"2597-2605","source":"Crossref","is-referenced-by-count":193,"title":["Efficacy of prolonged release melatonin in insomnia patients aged 55\u201380 years: quality of sleep and next-day alertness outcomes"],"prefix":"10.1185","volume":"23","author":[{"given":"Alan G","family":"Wade","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ian","family":"Ford","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gordon","family":"Crawford","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alex D","family":"McMahon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tali","family":"Nir","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Moshe","family":"Laudon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nava","family":"Zisapel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2007,9,14]]},"reference":[{"key":"CIT0001","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-5415.1982.tb03700.x"},{"key":"CIT0003","doi-asserted-by":"publisher","DOI":"10.1007\/s004060170052"},{"key":"CIT0004","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0404.2000.102004249.x"},{"issue":"2","key":"CIT0006","first-page":"S379","volume":"22","author":"Zammit GK","year":"1999","journal-title":"Sleep"},{"key":"CIT0007","first-page":"583","volume":"42","author":"Pilcher JJ","year":"1997","journal-title":"Sadowsky B. Sleep quality versus sleep quantity: relationships between sleep and measures of health, well-being and sleepiness in college students. J Psychosom Res"},{"key":"CIT0008","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.165.1.35"},{"key":"CIT0009","first-page":"63","volume":"3","author":"Krystal AD","year":"2007","journal-title":"J Clin Sleep Med"},{"key":"CIT0010","doi-asserted-by":"publisher","DOI":"10.1053\/smrv.2002.0274"},{"key":"CIT0011","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.38623.768588.47"},{"key":"CIT0012","doi-asserted-by":"publisher","DOI":"10.2165\/00023210-200013030-00005"},{"key":"CIT0013","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199701163360306"},{"key":"CIT0014","first-page":"330","volume":"15","author":"Nakagawa H","year":"1992","journal-title":"Sleep propensity free-runs with the temperature, melatonin and cortisol rhythms in a totally blind person. Sleep"},{"key":"CIT0015","doi-asserted-by":"publisher","DOI":"10.1177\/074873049701200104"},{"key":"CIT0016","first-page":"432","volume":"15","author":"Cajochen C","year":"2003","journal-title":"Role of melatonin in the regulation of human circadian rhythms and sleep. J Neuroendocrinol"},{"key":"CIT0017","first-page":"609","volume":"29","author":"Wyatt JK","year":"2006","journal-title":"Sleep-facilitating effect of exogenous melatonin in healthy young men and women is circadian-phase dependent. Sleep"},{"key":"CIT0018","doi-asserted-by":"publisher","DOI":"10.1016\/S0896-6273(00)80350-5"},{"key":"CIT0019","first-page":"R364","volume":"273","author":"Shochat T","year":"1997","journal-title":"Nocturnal melatonin onset is phase locked to the primary sleep gate. Am J Physiol"},{"key":"CIT0020","first-page":"410","volume":"31","author":"Gorfine T","year":"2006","journal-title":"Sleep-anticipating effects of melatonin in the human brain. Neuroimage"},{"key":"CIT0021","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-079X.2007.00446.x"},{"key":"CIT0022","doi-asserted-by":"publisher","DOI":"10.1016\/0006-3223(89)90178-9"},{"key":"CIT0023","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.309.6948.167"},{"key":"CIT0024","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-079X.1995.tb00179.x"},{"key":"CIT0026","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-1497.2005.0243.x"},{"key":"CIT0027","doi-asserted-by":"publisher","DOI":"10.1007\/BF00434408"},{"key":"CIT0028","doi-asserted-by":"publisher","DOI":"10.1002\/hup.455"},{"key":"CIT0029","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291700014379"},{"key":"CIT0030","first-page":"603","volume":"18","author":"Tarrasch R","year":"2003","journal-title":"Cross-cultural validation of the Leeds sleep evaluation questionnaire (LSEQ) in insomnia patients. Hum Psychopharmacol"},{"key":"CIT0031","first-page":"845","volume":"18","author":"Rombaut N","year":"1990","journal-title":"Med Sci Res"},{"key":"CIT0032","first-page":"3287","volume":"23","author":"Kieser M","year":"2004","journal-title":"Power and sample size determination when assessing the clinical relevance of trial results by \u2018responder analyses\u2019. Stat Med"},{"key":"CIT0033","doi-asserted-by":"publisher","DOI":"10.1046\/j.0962-1105.2003.00365.x"},{"key":"CIT0034","author":"Assocation WP","year":"1991","journal-title":"The management of insomnia"},{"key":"CIT0035","first-page":"237","volume":"23","author":"Jr Chesson A","year":"2000","journal-title":"An American Academy of Sleep Medicine report. Standards of Practice Committee of the American Academy of Sleep Medicine. Sleep"},{"key":"CIT0036","doi-asserted-by":"crossref","first-page":"1155","DOI":"10.1093\/sleep\/29.9.1155","volume":"29","author":"Buysse DJ","year":"2006","journal-title":"Sleep"},{"key":"CIT0037","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3999(02)00330-6"},{"key":"CIT0039","doi-asserted-by":"publisher","DOI":"10.1002\/mpr.145"},{"key":"CIT0040","first-page":"114","volume":"1","author":"Ancoli-Israel S","year":"1999","journal-title":"Zaleplon, A novel nonbenzodiazepine hypnotic, effectively treats insomnia in elderly patients without causing rebound effects. Prim Care Companion J Clin Psychiatry"},{"key":"CIT0041","doi-asserted-by":"publisher","DOI":"10.1016\/0166-4328(95)00017-N"},{"key":"CIT0042","doi-asserted-by":"publisher","DOI":"10.1016\/j.sleep.2006.01.003"}],"container-title":["Current Medical Research and Opinion"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.tandfonline.com\/doi\/pdf\/10.1185\/030079907X233098","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,2]],"date-time":"2019-05-02T22:55:47Z","timestamp":1556837747000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.tandfonline.com\/doi\/full\/10.1185\/030079907X233098"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,9,14]]},"references-count":38,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2007,8,13]]},"published-print":{"date-parts":[[2007,10]]}},"alternative-id":["10.1185\/030079907X233098"],"URL":"https:\/\/doi.org\/10.1185\/030079907x233098","relation":{},"ISSN":["0300-7995","1473-4877"],"issn-type":[{"value":"0300-7995","type":"print"},{"value":"1473-4877","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,9,14]]}}}