{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T16:35:55Z","timestamp":1778776555340,"version":"3.51.4"},"reference-count":72,"publisher":"Informa Healthcare","issue":"10","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Current Medical Research and Opinion"],"published-print":{"date-parts":[[2012,10,1]]},"DOI":"10.1185\/03007995.2012.729505","type":"journal-article","created":{"date-parts":[[2012,9,17]],"date-time":"2012-09-17T11:31:07Z","timestamp":1347881467000},"page":"1685-1697","source":"Crossref","is-referenced-by-count":20,"title":["Are fixed-dose combination antihypertensives suitable as first-line therapy?"],"prefix":"10.1185","volume":"28","author":[{"given":"Sverre E.","family":"Kjeldsen","sequence":"first","affiliation":[{"name":"Oslo University Hospital\rUllevaal, OsloNorway"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Franz H.","family":"Messerli","sequence":"additional","affiliation":[{"name":"Columbia University College of Physicians and Surgeons\rNew York, NYUSA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chern-En","family":"Chiang","sequence":"additional","affiliation":[{"name":"Taipei Veterans General Hospital, National Yang-Ming University\rTaipeiTaiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter A.","family":"Meredith","sequence":"additional","affiliation":[{"name":"Gardiner Institute, Western Infirmary\rGlasgow, ScotlandUK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lisheng","family":"Liu","sequence":"additional","affiliation":[{"name":"Fu Wai Hospital\rCAMS, BeijingChina"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"3197","published-online":{"date-parts":[[2012,9,26]]},"reference":[{"key":"CIT0001","first-page":"868","volume":"49","author":"Porapakkham Y","year":"2008","journal-title":"Singapore Med J"},{"key":"CIT0002","doi-asserted-by":"publisher","DOI":"10.1161\/01.HYP.0000252676.46043.18"},{"key":"CIT0003","doi-asserted-by":"publisher","DOI":"10.1097\/01.hjh.0000239286.02389.0f"},{"key":"CIT0004","first-page":"20","volume":"45","author":"Lim TO","year":"2004","journal-title":"Singapore Med J"},{"key":"CIT0005","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2012.04.140"},{"key":"CIT0006","doi-asserted-by":"publisher","DOI":"10.1038\/ajh.2012.2"},{"key":"CIT0007","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.b1665"},{"key":"CIT0008","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.0000116869.64771.5A"},{"key":"CIT0009","doi-asserted-by":"publisher","DOI":"10.3109\/10641969909060986"},{"key":"CIT0010","doi-asserted-by":"publisher","DOI":"10.1038\/sj.jhh.1001581"},{"key":"CIT0011","doi-asserted-by":"publisher","DOI":"10.2217\/WHE.11.25"},{"key":"CIT0012","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.108.128413"},{"key":"CIT0013","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.110.152892"},{"key":"CIT0014","doi-asserted-by":"publisher","DOI":"10.1097\/HJH.0b013e3281fc975a"},{"key":"CIT0015","doi-asserted-by":"publisher","DOI":"10.1097\/HJH.0b013e328333146d"},{"key":"CIT0016","doi-asserted-by":"publisher","DOI":"10.1161\/01.HYP.0000107251.49515.c2"},{"key":"CIT0017","doi-asserted-by":"publisher","DOI":"10.1016\/S0929-6646(10)60120-9"},{"key":"CIT0018","first-page":"579","volume":"39","author":"Liu LS","year":"2011","journal-title":"Zhonghua Xin Xue Guan Bing Za Zhi"},{"issue":"1","key":"CIT0019","first-page":"A6","volume":"13","author":"Jaffe MG","year":"2011","journal-title":"J Clin Hypertens"},{"key":"CIT0020","unstructured":"Canadian Hypertension Education Program. The 2012 CHEP recommendations. Hypertension Canada. Available at: http:\/\/www.hypertension.ca\/chep-recommendations. [Last accessed 22 March 2012]"},{"key":"CIT0021","doi-asserted-by":"publisher","DOI":"10.1016\/j.jash.2010.03.001"},{"key":"CIT0022","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-6175.2002.02045.x"},{"key":"CIT0023","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjmed.2008.09.038"},{"key":"CIT0024","doi-asserted-by":"publisher","DOI":"10.1097\/00001573-200111000-00006"},{"key":"CIT0025","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(10)62003-X"},{"key":"CIT0026","doi-asserted-by":"publisher","DOI":"10.1097\/HJH.0b013e3282f4edd7"},{"key":"CIT0027","doi-asserted-by":"publisher","DOI":"10.1097\/MBP.0b013e3282f6495b"},{"key":"CIT0028","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjhyper.2004.02.003"},{"key":"CIT0029","doi-asserted-by":"publisher","DOI":"10.1038\/jhh.2008.153"},{"key":"CIT0030","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.326.7404.1427"},{"key":"CIT0031","doi-asserted-by":"publisher","DOI":"10.1097\/MBP.0b013e32833a23d4"},{"key":"CIT0032","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinthera.2007.03.018"},{"key":"CIT0033","doi-asserted-by":"publisher","DOI":"10.1111\/j.1751-7176.2009.00098.x"},{"key":"CIT0034","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinthera.2008.04.002"},{"key":"CIT0035","doi-asserted-by":"publisher","DOI":"10.2165\/11598110-000000000-00000"},{"key":"CIT0036","doi-asserted-by":"publisher","DOI":"10.1097\/HJH.0b013e328342ef04"},{"key":"CIT0037","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0806182"},{"key":"CIT0038","unstructured":"Weber M. Effect of body mass on cardiovascular outcomes during hypertension treatment: an ACCOMPLISH analysis. American Society of Hypertension; May 19-22, 2012. New York, NY. Abstract LB-OR-03"},{"key":"CIT0039","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(05)67185-1"},{"key":"CIT0040","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(02)08089-3"},{"key":"CIT0041","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(04)16451-9"},{"key":"CIT0042","doi-asserted-by":"publisher","DOI":"10.1291\/hypres.31.1595"},{"key":"CIT0043","doi-asserted-by":"publisher","DOI":"10.1038\/jhh.2009.77"},{"key":"CIT0044","doi-asserted-by":"publisher","DOI":"10.1038\/jhh.2010.45"},{"key":"CIT0045","doi-asserted-by":"publisher","DOI":"10.1097\/00004872-200502000-00028"},{"key":"CIT0046","doi-asserted-by":"publisher","DOI":"10.1038\/jhh.2010.19"},{"key":"CIT0047","doi-asserted-by":"publisher","DOI":"10.1038\/jhh.2010.64"},{"key":"CIT0048","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(04)16456-8"},{"key":"CIT0049","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.111.177592"},{"key":"CIT0050","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-148-1-200801010-00189"},{"key":"CIT0051","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0801317"},{"key":"CIT0052","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjmed.2009.06.032"},{"key":"CIT0053","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjmed.2010.08.007"},{"key":"CIT0054","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.108.123455"},{"key":"CIT0055","doi-asserted-by":"publisher","DOI":"10.3111\/13696998.2012.689792"},{"key":"CIT0056","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjmed.2006.08.033"},{"key":"CIT0057","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.109.139816"},{"key":"CIT0058","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.112.194167"},{"key":"CIT0059","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinthera.2007.12.017"},{"key":"CIT0060","doi-asserted-by":"publisher","DOI":"10.3109\/10641963.2010.531849"},{"key":"CIT0061","doi-asserted-by":"publisher","DOI":"10.1185\/03007995.2010.487391"},{"key":"CIT0062","doi-asserted-by":"publisher","DOI":"10.1111\/1755-5922.12003"},{"key":"CIT0063","first-page":"204","volume":"18","author":"Dickson M","year":"2008","journal-title":"Ethn Dis"},{"key":"CIT0064","doi-asserted-by":"publisher","DOI":"10.1038\/jhh.2009.109"},{"key":"CIT0065","doi-asserted-by":"publisher","DOI":"10.2165\/00129784-200808010-00006"},{"key":"CIT0066","doi-asserted-by":"publisher","DOI":"10.1291\/hypres.28.585"},{"key":"CIT0067","first-page":"298","volume":"21","author":"Meredith P","year":"2010","journal-title":"Cardiovasc J Afr"},{"key":"CIT0068","doi-asserted-by":"publisher","DOI":"10.1161\/01.HYP.0000236119.96301.f2"},{"key":"CIT0069","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.160.12.1842"},{"key":"CIT0070","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-154-8-201104190-00335"},{"key":"CIT0071","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.109.131300"},{"key":"CIT0072","doi-asserted-by":"publisher","DOI":"10.2165\/11204350-000000000-00000"}],"container-title":["Current Medical Research and Opinion"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1185\/03007995.2012.729505","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,9,6]],"date-time":"2020-09-06T22:51:47Z","timestamp":1599432707000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1185\/03007995.2012.729505"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,9,26]]},"references-count":72,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2012,10,1]]}},"alternative-id":["10.1185\/03007995.2012.729505"],"URL":"https:\/\/doi.org\/10.1185\/03007995.2012.729505","relation":{},"ISSN":["0300-7995","1473-4877"],"issn-type":[{"value":"0300-7995","type":"print"},{"value":"1473-4877","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,9,26]]}}}