{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,2]],"date-time":"2025-11-02T16:40:10Z","timestamp":1762101610665},"reference-count":39,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2014,10,2]],"date-time":"2014-10-02T00:00:00Z","timestamp":1412208000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Headache Pain"],"published-print":{"date-parts":[[2014,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n          <jats:sec>\n            <jats:title>Background<\/jats:title>\n            <jats:p>The peripheral and central origins of pain in cluster headache (CH) have been a matter of much debate. The development and application of functional imaging techniques have provided more evidence supporting the hypothesis that CH is not a disorder exclusively peripheral in origin, and in fact central regions might be more important. Event-related potentials confer advantages in the functional evaluation of the cortex, but few studies thus far have employed this method in cluster headache.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods<\/jats:title>\n            <jats:p>Seventeen cluster patients (15 males; mean age\u2009=\u200935.4\u00a0years) and 15 age-matched healthy participants (13 males; mean age\u2009=\u200934.6\u00a0years) were recruited. A visual oddball paradigm was employed to analyze target processing using event-related potentials. We investigated the P3\/P3d components in the experiment.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results<\/jats:title>\n            <jats:p>P3\/P3d amplitudes were decreased in CH patients (P3, 3.82\u00a0\u03bcV; P3d, 5.8\u00a0\u03bcV) compared with controls (P3, 7.28\u00a0\u03bcV; P3d, 8.95\u00a0\u03bcV), <jats:italic>F<\/jats:italic>(1,30)\u2009=\u20094.919, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05, \u03b72\u2009=\u20090.141 for P3 and <jats:italic>F<\/jats:italic>(1,30)\u2009=\u20098.514, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05, \u03b72\u2009=\u20090.221 for P3d, respectively). Moreover, the amplitudes of P3\/P3d were no significantl difference in the side of pain as compared to contralateral one (p\u2009&gt;\u20090.05).<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusions<\/jats:title>\n            <jats:p>These results provide evidence of dysfunction in the cognitive processing of CH patients, which may also contribute to the pathophysiology of CH.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1186\/1129-2377-15-66","type":"journal-article","created":{"date-parts":[[2014,10,2]],"date-time":"2014-10-02T13:01:38Z","timestamp":1412254898000},"update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Cognitive processing of cluster headache patients: evidence from event-related potentials"],"prefix":"10.1186","volume":"15","author":[{"given":"Rongfei","family":"Wang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhao","family":"Dong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaoyan","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ruozhuo","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mingjie","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jinglong","family":"Wu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shengyuan","family":"Yu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2014,10,2]]},"reference":[{"key":"1010_CR1","doi-asserted-by":"publisher","first-page":"e50898","DOI":"10.1371\/journal.pone.0050898","volume":"7","author":"Z Dong","year":"2012","unstructured":"Dong Z, Di H, Dai W, Liang J, Pan M, Zhang M, Zhou Z, Li Z, Liu R, Yu S: Application of ICHD-II criteria in a headache clinic of China. 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