{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T16:16:31Z","timestamp":1770826591910,"version":"3.50.1"},"reference-count":19,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2006,3,28]],"date-time":"2006-03-28T00:00:00Z","timestamp":1143504000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Respir Res"],"published-print":{"date-parts":[[2006,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n          <jats:sec>\n            <jats:title>Background<\/jats:title>\n            <jats:p>Only few studies have assessed the relative impact of prenatal and postnatal exposure to tobacco smoke on the child's later asthma or chronic respiratory symptoms and to our knowledge no studies have elaborated respiratory infections and allergies in this context.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Objective<\/jats:title>\n            <jats:p>To assess the effects of prenatal and postnatal exposure to tobacco smoke on respiratory health of Russian school children.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods<\/jats:title>\n            <jats:p>We studied a population of 5951 children (8 to12 years old) from 9 Russian cities, whose parents answered a questionnaire on their children's respiratory health, home environment, and housing characteristics. The main health outcomes were asthma, allergies, chronic respiratory symptoms, chronic bronchitis, and upper respiratory infections. We used adjusted odds ratios (ORs) from logistic regression analyses as measures of effect.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results<\/jats:title>\n            <jats:p>Prenatal exposure due to maternal smoking had the strongest effects on asthma (adjusted OR 2.46, 95% CI 1.19\u20135.08), chronic bronchitis (adjusted OR 1.45, 95% CI 1.08\u20131.96) and respiratory symptoms, such as wheezing (adjusted OR 1.30, 95% CI 0.90\u20131.89). The associations were weaker for exposure during early-life (adjusted ORs 1.38\/1.27\/1.15 respectively) and after 2 years of age (adjusted ORs 1.45\/1.34\/1.18) compared to prenatal exposure and the weakest or non-existent for current exposure (adjusted ORs 1.05\/1.09\/1.06). Upper respiratory infections were associated more strongly with early-life exposure (adjusted OR 1.25, 95% CI 1.09\u20131.42) than with prenatal (adjusted OR 0.74, 95% CI 0.54\u20131.01) or current exposure (adjusted OR1.05, 95% CI 0.92\u20131.20). The risk of allergies was also related to early life exposure to tobacco smoke (adjusted OR 1.26, 95% CI 1.13\u20131.42).<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusion<\/jats:title>\n            <jats:p>Adverse effects of tobacco smoke on asthma, chronic bronchitis, and chronic respiratory symptoms are strongest when smoking takes place during pregnancy. The relations are weaker for exposure during early-life and after 2 years of age and weakest or non-existent for current exposure.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1186\/1465-9921-7-48","type":"journal-article","created":{"date-parts":[[2006,4,6]],"date-time":"2006-04-06T12:50:36Z","timestamp":1144327836000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":67,"title":["Prenatal and postnatal tobacco smoke exposure and respiratory health in Russian children"],"prefix":"10.1186","volume":"7","author":[{"given":"Jouni JK","family":"Jaakkola","sequence":"first","affiliation":[]},{"given":"Anna A","family":"Kosheleva","sequence":"additional","affiliation":[]},{"given":"Boris A","family":"Katsnelson","sequence":"additional","affiliation":[]},{"given":"Sergey V","family":"Kuzmin","sequence":"additional","affiliation":[]},{"given":"Larissa I","family":"Privalova","sequence":"additional","affiliation":[]},{"given":"John D","family":"Spengler","sequence":"additional","affiliation":[]}],"member":"297","published-online":{"date-parts":[[2006,3,28]]},"reference":[{"key":"439_CR1_439","first-page":"663","volume":"65","author":"MS Kramer","year":"1987","unstructured":"Kramer MS: Determinants of low birth weight: methodological assessment and meta-analysis.\nBulletin of the World Health Organization 1987, 65:663\u2013737.","journal-title":"Bulletin of the World Health Organization"},{"key":"439_CR2_439","doi-asserted-by":"publisher","first-page":"1060","DOI":"10.1016\/S0140-6736(96)04446-7","volume":"348","author":"SM Stick","year":"1996","unstructured":"Stick SM, Burton PR, Gurrin L, Sly PD, LeSouef PN: Effects of maternal smoking during pregnancy and a family history of asthma on respiratory function in newborn infants.\nLancet 1996, 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