{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T02:20:19Z","timestamp":1787019619283,"version":"build-2736575974"},"reference-count":31,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2006,5,17]],"date-time":"2006-05-17T00:00:00Z","timestamp":1147824000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Respir Res"],"published-print":{"date-parts":[[2006,12]]},"DOI":"10.1186\/1465-9921-7-77","type":"journal-article","created":{"date-parts":[[2006,5,17]],"date-time":"2006-05-17T14:24:29Z","timestamp":1147875869000},"source":"Crossref","is-referenced-by-count":69,"title":["Tuberculosis contact investigation with a new, specific blood test in a low-incidence population containing a high proportion of BCG-vaccinated persons"],"prefix":"10.1186","volume":"7","author":[{"given":"R","family":"Diel","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A","family":"Nienhaus","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C","family":"Lange","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K","family":"Meywald-Walter","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M","family":"For\u00dfbohm","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T","family":"Schaberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2006,5,17]]},"reference":[{"key":"468_CR1_468","doi-asserted-by":"publisher","first-page":"1104","DOI":"10.1086\/517405","volume":"177","author":"WZ Bradford","year":"1988","unstructured":"Bradford WZ, Koehler J, El-Hajj H, Hopewell PC, Reingold AL, Agasino CB, Cave MD, Rane S, Yang Z, Crane CM, Small PM: Dissemination of Mycobacterium tuberculosis across the San Francisco Bay Area. J Infect Dis 1988, 177:1104\u20131107.","journal-title":"J Infect Dis"},{"key":"468_CR2_468","doi-asserted-by":"crossref","first-page":"486","DOI":"10.1128\/JCM.36.2.486-492.1998","volume":"36","author":"MC Gutierrez","year":"1998","unstructured":"Gutierrez MC, Vincent V, Aubert D, Bizet J, Gaillot O, Lebrun L, Le Pendeven C, Le Pennec MP, Mathieu D, Offredo C, Pangon B, Pierre-Audigier C: Molecular fingerprinting of Mycobacterium tuberculosis and risk factors for tuberculosis transmission in Paris, France, and surrounding area. J Clin Microbiol 1998, 36:486\u2013492.","journal-title":"J Clin Microbiol"},{"key":"468_CR3_468","doi-asserted-by":"publisher","first-page":"726","DOI":"10.1086\/314930","volume":"3","author":"D Van Soolingen","year":"1999","unstructured":"Van Soolingen D, Borgdorff MW, de Haas PE, Sebek MM, Veen J, Dessens M, Kremer K, van Embden JD: Molecular epidemiology of tuberculosis in the Netherlands: a nationwide study from 1993 through 1997. J Infect Dis 1999, 3:726\u2013736.","journal-title":"J Infect Dis"},{"key":"468_CR4_468","doi-asserted-by":"publisher","first-page":"1710","DOI":"10.1056\/NEJM199406163302403","volume":"330","author":"D Alland","year":"1994","unstructured":"Alland D, Kalkut GE, Moss AR, McAdam RA, Hahn JA, Bosworth W, Drucker E, Bloom BR: Transmission of tuberculosis in New York City. An analysis by DNA fingerprinting and conventional epidemiological methods. N Engl J Med 1994, 330:1710\u20131716.","journal-title":"N Engl J Med"},{"key":"468_CR5_468","doi-asserted-by":"publisher","first-page":"1703","DOI":"10.1056\/NEJM199406163302402","volume":"330","author":"PM Small","year":"1994","unstructured":"Small PM, Hopewell PC, Singh SP, Paz A, Parsonnet J, Ruston DC, Schecter GF, Daley CL, Schoolnik GK: The epidemiology of tuberculosis in San Francisco. A population-based study using conventional and molecular methods. N Engl J Med 1994, 330:1703\u20131709.","journal-title":"N Engl J Med"},{"key":"468_CR6_468","doi-asserted-by":"publisher","first-page":"1099","DOI":"10.1016\/S0140-6736(00)02742-2","volume":"356","author":"P Andersen","year":"2000","unstructured":"Andersen P, Munk ME, Pollock JM, Doherty TM: Specific immune-based diagnosis of tuberculosis. Lancet 2000, 356:1099\u20131104.","journal-title":"Lancet"},{"key":"468_CR7_468","doi-asserted-by":"publisher","first-page":"184","DOI":"10.1086\/426139","volume":"40","author":"KA Wilkinson","year":"2005","unstructured":"Wilkinson KA, Wilkinson RJ, Pathan A, Ewer K, Prakash M, Klenermann P, Maskell N, Davies R, Pasvol G, Lalvani A: Ex vivo characterization of early secretory antigen target 6-specific T cells at sites of active disease in pleural tuberculosis. Clin Infect Dis 2005, 40:184\u2013187.","journal-title":"Clin Infect Dis"},{"key":"468_CR8_468","doi-asserted-by":"publisher","first-page":"59","DOI":"10.1164\/rccm.200402-179OC","volume":"170","author":"T Mori","year":"2004","unstructured":"Mori T, Sakatani M, Yamagishi F, Takashima T, Kawabe Y, Nagao K, Shigeto E, Harada N, Mitarai S, Okada M, Suzuki K, Inoue Y, Tsuyuguchi K, Sasaki Y, Mazurek GH, Tsuyuguchi I: Specific detection of tuberculosis infection: an interferon-gamma-based assay using new antigens. Am J Respir Crit Care Med 2004, 170:59\u201364.","journal-title":"Am J Respir Crit Care Med"},{"key":"468_CR9_468","doi-asserted-by":"publisher","first-page":"631","DOI":"10.1164\/rccm.200502-196OC","volume":"172","author":"G Ferrara","year":"2005","unstructured":"Ferrara G, Losi M, Meacci M, Meccugni B, Meccugni B, Piro R, Roversi P, Bergamini BM, D'Amico R, Marchegiano P, Rumpianesi F, Fabbri LM, Richeldi L: Routine hospital use of a commercial whole blood interferon-{gamma} assay for tuberculosis infection. Am J Respir Crit Care Med 2005, 172:631\u2013635.","journal-title":"Am J Respir Crit Care Med"},{"key":"468_CR10_468","doi-asserted-by":"publisher","first-page":"2756","DOI":"10.1001\/jama.293.22.2756","volume":"293","author":"YA Kang","year":"2005","unstructured":"Kang YA, Lee HW, Yoon HI, Cho B, Han SK, Shim YS, Yim JJ: Discrepancy between the tuberculin skin test and the whole-blood interferon gamma assay for the diagnosis of latent tuberculosis infection in an intermediate tuberculosis-burden country. JAMA 2005, 293:2756\u20132761.","journal-title":"JAMA"},{"key":"468_CR11_468","first-page":"462","volume":"5","author":"I Brock","year":"2001","unstructured":"Brock I, Munk ME, Kok-Jensen A, Andersen P: Performance of whole blood IFN-gamma test for tuberculosis diagnosis based on PPD or the specific antigens ESAT-6 and CFP-10. Int J Tuberc Lung Dis 2001, 5:462\u2013467.","journal-title":"Int J Tuberc Lung Dis"},{"key":"468_CR12_468","first-page":"527","volume":"80","author":"K Funayama","year":"2005","unstructured":"Funayama K, Tsujimoto A, Mori M, Yamamoto H, Fujiwara K, Nishimura T, Hasegawa N, Horiguchi I, Mori T, Marui E: Usefulness of QuantiFERON \u00ae TB-2G in contact investigation of a tuberculosis outbreak in a university. Kekkaku 2005, 80:527\u2013534.","journal-title":"Kekkaku"},{"key":"468_CR13_468","doi-asserted-by":"publisher","first-page":"65","DOI":"10.1164\/rccm.200402-232OC","volume":"170","author":"I Brock","year":"2004","unstructured":"Brock I, Weldingh K, Lillebaek T, Follmann F, Andersen P: Comparison of tuberculin skin test and new specific blood test in tuberculosis contacts. Am J Respir Crit Care Med 2004, 170:65\u201369.","journal-title":"Am J Respir Crit Care Med"},{"key":"468_CR14_468","unstructured":"Institut f\u00fcr Hygiene und Umwelt, Hamburg: Meldepflichtige Infektionskrankheiten in Hamburg 2004. Epidemiologischer Bericht 9."},{"key":"468_CR15_468","unstructured":"Statistische \u00c4mter des Bundes und der L\u00e4nder: Gebiet und Bev\u00f6lkerung \u2013 Ausl\u00e4ndische Bev\u00f6lkerung. Ausgabe 2005."},{"key":"468_CR16_468","doi-asserted-by":"publisher","first-page":"465","DOI":"10.1164\/ajrccm.158.2.9801062","volume":"158","author":"A Behr","year":"1998","unstructured":"Behr A, Hopewell PC, Paz EA, Kamamura LM, Schecter GF, Small PM: Predictive value of contact investigation for identifying recent transmission of Mycobacterium tuberculosis . Am J Respir Crit Care Med 1998, 158:465\u2013469.","journal-title":"Am J Respir Crit Care Med"},{"key":"468_CR17_468","unstructured":"[ http:\/\/www.cellestis.com ]"},{"key":"468_CR18_468","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-662-05745-2","volume-title":"Angewandte Statistik: Anwendung statistischer Methoden","author":"L Sachs","year":"2002","unstructured":"Sachs L: Angewandte Statistik: Anwendung statistischer Methoden. 10th edition. Berlin, Springer; 2002.","edition":"10"},{"key":"468_CR19_468","unstructured":"Euro TB (CESES\/KNCV) and the national coordinators for tuberculosis surveillance in the WHO European RegionReport on tuberculosis cases notified in 1996 1998."},{"key":"468_CR20_468","doi-asserted-by":"publisher","first-page":"255","DOI":"10.1055\/s-2004-818448","volume":"58","author":"T Schaberg","year":"2004","unstructured":"Schaberg T, Hauer B, Loddenkemper R, Brendel A, Haas W, Just HM, Loytved G, Meyer C, Rieder HL, Ruden H, Sagebiel D: Latent tuberculosis infection: recommendations for preventive therapy in adults in Germany. Pneumologie 2004, 58:255\u201370.","journal-title":"Pneumologie"},{"key":"468_CR21_468","doi-asserted-by":"crossref","unstructured":"American Thoracic Society. Targeted tuberculin testing and treatment of latent tuberculosis infectionAm J Respir Crit Care Med 2000, 161:S221\u2013247.","DOI":"10.1164\/ajrccm.161.supplement_3.ats600"},{"key":"468_CR22_468","doi-asserted-by":"publisher","first-page":"1168","DOI":"10.1016\/S0140-6736(03)12950-9","volume":"361","author":"K Ewer","year":"2003","unstructured":"Ewer K, Deeks J, Alvarez L, Bryant G, Waller S, Andersen P, Monk P, Lalvani A: Comparison of T-cell-based assay with tuberculin skin test for diagnosis of Mycobacterium tuberculosis infection in a school tuberculosis outbreak. Lancet 2003, 361:1168\u20131173.","journal-title":"Lancet"},{"key":"468_CR23_468","doi-asserted-by":"crossref","first-page":"934","DOI":"10.1128\/CDLI.6.6.934-937.1999","volume":"6","author":"PD Johnson","year":"1999","unstructured":"Johnson PD, Stuart RL, Grayson ML, Olden D, Clancy A, Ravn P, Andersen P, Britton WJ, Rothel JS: Tuberculin-purified protein derivative-, MPT-64-, and ESAT-6-stimulated gamma interferon responses in medical students before and after Mycobacterium bovis BCG vaccination and in patients with tuberculosis. Clin Diagn Lab Immunol 1999, 6:934\u2013937.","journal-title":"Clin Diagn Lab Immunol"},{"key":"468_CR24_468","first-page":"1242","volume":"9","author":"JP Zellweger","year":"2005","unstructured":"Zellweger JP, Zellweger A, Ansermet S, De Senarclens B, Wrighton-Smith P: Contact tracing using a new T-cell-based test: better correlation with tuberculosis exposure than the tuberculin test. Int J Tuberc Lung Dis 2005, 9:1242\u20131247.","journal-title":"Int J Tuberc Lung Dis"},{"key":"468_CR25_468","doi-asserted-by":"publisher","first-page":"273","DOI":"10.1086\/427030","volume":"490","author":"PC Hill","year":"2005","unstructured":"Hill PC, Fox A, Jeffreis DJ, Jackson-Silah D, Lugos MD, Owiafe PK, Donkor SA, Hammond AS, Corrah T, Adegbola RA, McAdam KP, Brookes RH: Quantitative T cell assay reflects infectious load of Mycobacterium tuberculosis in an endemic case contact model. Clin Infect Dis 2005, 490:273\u2013278.","journal-title":"Clin Infect Dis"},{"key":"468_CR26_468","first-page":"1","volume":"99","author":"LB Edwards","year":"1969","unstructured":"Edwards LB, Acquviva FA, Livesay VT, Cross FW, Palmer CE: An atlas of sensitivity to tuberculin, PPD-B, and histoplasmin in the United States. Am Rev Respir Dis 1969, 99:1\u2013111.","journal-title":"Am Rev Respir Dis"},{"key":"468_CR27_468","doi-asserted-by":"publisher","first-page":"371","DOI":"10.1016\/0962-8479(93)90079-D","volume":"74","author":"LO Larsson","year":"1993","unstructured":"Larsson LO, Bentzon MW, Lind A, Magnusson M, Sandegard G, Skoogh BE, Boethius G: Sensitivity to sensitins and tuberculin in Swedish children. Part 5: A study of school children in an inland rural area. Tuber Lung Dis 1993, 74:371\u2013376.","journal-title":"Tuber Lung Dis"},{"key":"468_CR28_468","doi-asserted-by":"publisher","first-page":"87","DOI":"10.1016\/0962-8479(92)90061-N","volume":"73","author":"M Tala-Heikkila","year":"1992","unstructured":"Tala-Heikkila M, Nurmela T, Misljenovic O, Bleiker MA, Tala E: Sensitivity to PPD tuberculin and M. scrofulaceum sensitin in schoolchildren BCG vaccinated at birth. Tuber Lung Dis 1992, 73:87\u201393.","journal-title":"Tuber Lung Dis"},{"key":"468_CR29_468","doi-asserted-by":"publisher","first-page":"540","DOI":"10.1016\/0962-8479(95)90531-6","volume":"76","author":"J Bruins","year":"1995","unstructured":"Bruins J, Gribnau JH, Bwire R: Investigation into typical and atypical tuberculin sensitivity in the Royal Netherlands Army, resulting in a more rational indication for isoniazid prophylaxis. Tuber Lung Dis 1995, 76:540\u2013544.","journal-title":"Tuber Lung Dis"},{"key":"468_CR30_468","first-page":"1122","volume":"5","author":"Reyn Von","year":"2001","unstructured":"Von Reyn, Horsburgh CR, Olivier KN, Barnes PF, Waddell R, Warren C, Tvaroha S, Jaeger AS, Lein AD, Alexander LN, Weber DJ, Tosteson AN: Skin test reactions to Mycobacterium tuberculosis purified protein derivative and Mycobacterium avium sensitin among health care workers and medical students in the United States. Int J Tuberc Lung Dis 2001, 5:1122\u20131128.","journal-title":"Int J Tuberc Lung Dis"},{"key":"468_CR31_468","doi-asserted-by":"publisher","first-page":"195","DOI":"10.1097\/01.mcp.0000158726.13159.5e","volume":"11","author":"K Dheda","year":"2005","unstructured":"Dheda K, Udwadia ZF, Huggett JF, Johnson MA, Rook GA: Utility of the antigen-specific interferon-gamma assay for the management of tuberculosis. Curr Opin Pulm Med 2005, 11:195\u2013202.","journal-title":"Curr Opin Pulm Med"}],"container-title":["Respiratory Research"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1465-9921-7-77.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1186\/1465-9921-7-77\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1465-9921-7-77","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,4,14]],"date-time":"2020-04-14T18:30:06Z","timestamp":1586889006000},"score":1,"resource":{"primary":{"URL":"http:\/\/respiratory-research.biomedcentral.com\/articles\/10.1186\/1465-9921-7-77"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,5,17]]},"references-count":31,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2006,12]]}},"alternative-id":["468"],"URL":"https:\/\/doi.org\/10.1186\/1465-9921-7-77","relation":{},"ISSN":["1465-993X"],"issn-type":[{"value":"1465-993X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,5,17]]},"article-number":"77"}}