{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,28]],"date-time":"2026-05-28T00:27:20Z","timestamp":1779928040647,"version":"3.53.1"},"reference-count":33,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2009,11,1]],"date-time":"2009-11-01T00:00:00Z","timestamp":1257033600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/2.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BMC Bioinformatics"],"published-print":{"date-parts":[[2009,12]]},"DOI":"10.1186\/1471-2105-10-368","type":"journal-article","created":{"date-parts":[[2009,11,3]],"date-time":"2009-11-03T07:13:40Z","timestamp":1257232420000},"source":"Crossref","is-referenced-by-count":60,"title":["A biosegmentation benchmark for evaluation of bioimage analysis methods"],"prefix":"10.1186","volume":"10","author":[{"given":"Elisa","family":"Drelie Gelasca","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Boguslaw","family":"Obara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dmitry","family":"Fedorov","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kristian","family":"Kvilekval","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"BS","family":"Manjunath","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2009,11,1]]},"reference":[{"issue":"11","key":"3098_CR1","doi-asserted-by":"publisher","first-page":"1405","DOI":"10.1109\/TMI.2006.883282","volume":"25","author":"P Jannin","year":"2006","unstructured":"Jannin P, Krupinski E, Warfield S: Guest editorial validation in medical image processing. IEEE Transactions on Medical Imaging 2006, 25(11):1405\u20131409.","journal-title":"IEEE Transactions on Medical Imaging"},{"key":"3098_CR2","doi-asserted-by":"crossref","DOI":"10.1007\/978-3-540-40997-7","volume-title":"Medical image understanding technology, it Volume 156 of Studies in Fuzziness and Soft Computing","author":"R Tadeusiewicz","year":"2004","unstructured":"Tadeusiewicz R, Ogiela MR: Medical image understanding technology, it Volume 156 of Studies in Fuzziness and Soft Computing. Berlin-Heidelberg-New York: Springer-Verlag; 2004."},{"key":"3098_CR3","volume-title":"IEEE Transactions on Pattern Analysis and Machine Intelligence","author":"PJ Phillips","year":"2000","unstructured":"Phillips PJ, Moon H, Rauss PJ, Rizvi S: The FERET evaluation methodology for face recognition algorithms. IEEE Transactions on Pattern Analysis and Machine Intelligence 2000., 22(10):"},{"key":"3098_CR4","first-page":"416","volume":"2","author":"D Martin","year":"2001","unstructured":"Martin D, Fowlkes C, Tal D, Malik J: A database of human segmented natural images and its application to evaluating segmentation algorithms and measuring ecological statistics. International Conference on Computer Vision, Vancouver, BC, Canada 2001, 2: 416\u2013423.","journal-title":"International Conference on Computer Vision, Vancouver, BC, Canada"},{"issue":"4","key":"3098_CR5","doi-asserted-by":"publisher","first-page":"594","DOI":"10.1109\/TPAMI.2006.79","volume":"28","author":"L Fei-Fei","year":"2006","unstructured":"Fei-Fei L, Fergus R, Perona P: One-shot learning of object categories. IEEE Transactions on Pattern Analysis and Machine Intelligence 2006, 28(4):594.","journal-title":"IEEE Transactions on Pattern Analysis and Machine Intelligence"},{"key":"3098_CR6","doi-asserted-by":"publisher","first-page":"31","DOI":"10.1016\/S0010-4825(02)00060-4","volume":"33","author":"TW Nattkemper","year":"2003","unstructured":"Nattkemper TW, Twellmann T, Schubert W, Ritter H: Human vs. machine: Evaluation of uorescence micrographs. Computers in Biology and Medicine 2003, 33: 31\u201343.","journal-title":"Computers in Biology and Medicine"},{"key":"3098_CR7","unstructured":"NIBIB's image and clinical data2008. [ http:\/\/www.nibib.nih.gov\/Research\/Resources\/ImageClinData ]"},{"key":"3098_CR8","unstructured":"The cell centered database2002. [ http:\/\/www.ccdb.ucsd.edu ]"},{"key":"3098_CR9","unstructured":"Mouse retina SAGE library2004. [ http:\/\/cepko.med.harvard.edu\/ ]"},{"key":"3098_CR10","unstructured":"Protein classification benchmark collection2006. [ http:\/\/net.icgeb.org\/benchmark ]"},{"key":"3098_CR11","unstructured":"Broad bioimage benchmark collection2008. [ http:\/\/www.broad.mit.edu\/bbbc ]"},{"key":"3098_CR12","unstructured":"Face recognition grand challenge2008. [ http:\/\/face.nist.gov\/frgc ]"},{"key":"3098_CR13","unstructured":"Face recognition vendor test2006. [ http:\/\/face.nist.gov\/frvt ]"},{"key":"3098_CR14","unstructured":"Iris challenge evaluation[ http:\/\/iris.nist.gov\/ice ]"},{"key":"3098_CR15","unstructured":"FRVT 2006 and ICE 2006 large-scale results In Tech. Rep. NISTIR 7408. National Institute of Standards and Technology; 2007."},{"key":"3098_CR16","unstructured":"BioChange[ ftp:\/\/ftp.nist.gov\/pub\/itl\/biochange\/Biochange2008\/Biochange08-BenchmarkingProtocol.pdf ]"},{"key":"3098_CR17","first-page":"1816","volume-title":"IEEE International Conference on Image Processing, San Diego, CA, USA","author":"ED Gelasca","year":"2008","unstructured":"Gelasca ED, Byun J, Obara B, Manjunath BS: Evaluation and benchmark for biological image segmentation. IEEE International Conference on Image Processing, San Diego, CA, USA 2008, 1816\u20131819."},{"key":"3098_CR18","volume-title":"Bisque: bio-image semantic query user environment","author":"K Kvilekval","year":"2008","unstructured":"Kvilekval K, Fedorov D, Obara B, Manjunath BS, Singh AK: Bisque: bio-image semantic query user environment.2008. [ http:\/\/bioimage.ucsb.edu\/bisque ]"},{"key":"3098_CR19","unstructured":"UCSB biosegmentation benchmark2008. [ http:\/\/bioimage.ucsb.edu\/biosegmentation ]"},{"key":"3098_CR20","doi-asserted-by":"publisher","first-page":"253","DOI":"10.1038\/nrc1317","volume":"4","author":"MA Jordan","year":"2004","unstructured":"Jordan MA, Wilson L: Microtubules as a target for anticancer drugs. Nature Reviews Cancer 2004, 4: 253\u2013265.","journal-title":"Nature Reviews Cancer"},{"key":"3098_CR21","volume-title":"IEEE Computer Society Conference on on Computer Vision and Pattern Recognition, New York, NY, USA","author":"A Altinok","year":"2006","unstructured":"Altinok A, El-Saban M, Peck A, Wilson L, Feinstein S, Manjunath BS, Rose K: Activity analysis in microtubule videos by mixture of hidden Markov models. IEEE Computer Society Conference on on Computer Vision and Pattern Recognition, New York, NY, USA 2006., 2:"},{"issue":"16","key":"3098_CR22","doi-asserted-by":"publisher","first-page":"9548","DOI":"10.1073\/pnas.1633508100","volume":"100","author":"D Panda","year":"2003","unstructured":"Panda D, Samuel JC, MMassie , Feinstein SC, Wilson L: Differential regulation of microtubule dynamics by three- and four-repeat tau: Implications for normal neuronal development and the onset of neurodegenerative disease. Proceedings of the National Academy of Sciences of the USA 2003, 100(16):9548\u20139553.","journal-title":"Proceedings of the National Academy of Sciences of the USA"},{"key":"3098_CR23","first-page":"561","volume-title":"IEEE International Conference on Acoustic, Speech and Signal Processing, Las Vegas, NV, USA","author":"ME Sargin","year":"2008","unstructured":"Sargin ME, Altinok A, Rose K, Manjunath BS: Deformable trellis: Open contour tracking in bio-image sequences. IEEE International Conference on Acoustic, Speech and Signal Processing, Las Vegas, NV, USA 2008, 561\u2013564."},{"issue":"3","key":"3098_CR24","doi-asserted-by":"publisher","first-page":"1305","DOI":"10.1167\/iovs.06-0591","volume":"48","author":"KH Eibl","year":"2007","unstructured":"Eibl KH, Lewis GP, Betts K, Linberg KA, Gandorfer A, Kampik A, Fisher SK: The effect of alkylphosphocholines on intraretinal proliferation initiated by experimental retinal detachment. Investigative Ophthalmology and Visual Science 2007, 48(3):1305\u20131311.","journal-title":"Investigative Ophthalmology and Visual Science"},{"key":"3098_CR25","first-page":"949","volume":"12","author":"J Byun","year":"2006","unstructured":"Byun J, Verardo MR, Sumengen B, Lewis GP, Manjunath BS, Fisher SK: Automated tool for the detection of cell nuclei in digital microscopic images: Application to retinal images. Molecular Vision 2006, 12: 949\u2013960.","journal-title":"Molecular Vision"},{"issue":"19","key":"3098_CR26","doi-asserted-by":"publisher","first-page":"3539","DOI":"10.1242\/dev.010298","volume":"134","author":"SP Gordon","year":"2007","unstructured":"Gordon SP, Heisler MG, Reddy GV, Ohno C, Das P, Meyerowitz EM: Pattern formation during de novo assembly of the Arabidopsis shoot meristem. Development 2007, 134(19):3539\u20133548.","journal-title":"Development"},{"key":"3098_CR27","volume-title":"Workshop on Bio-Image Informatics: Biological Imaging, Computer Vision and Data Mining, Santa Barbara, CA, USA","author":"B Obara","year":"2008","unstructured":"Obara B, Byun J, Fedorov D, Manjunath BS: Automatic nuclei detection and data flow in Bisquik system. Workshop on Bio-Image Informatics: Biological Imaging, Computer Vision and Data Mining, Santa Barbara, CA, USA 2008."},{"key":"3098_CR28","volume-title":"PhD thesis","author":"L Boucheron","year":"2007","unstructured":"Boucheron L: Object- and spatial-level quantitative analysis of multispectral histopathology images for detection and characterization of cancer. PhD thesis. University of Santa Barbara, CA, USA; 2007."},{"key":"3098_CR29","first-page":"208","volume":"4841","author":"LE Boucheron","year":"2007","unstructured":"Boucheron LE, Harvey NR, Manjunath BS: A quantitative object-level metric for segmentation performance and its application to cell nuclei. International Symposium on Visual Computing, Lake Tahoe, NV, USA 2007, 4841: 208\u2013219.","journal-title":"International Symposium on Visual Computing, Lake Tahoe, NV, USA"},{"key":"3098_CR30","volume-title":"IEEE International Conference on Image Processing, San Antonio, TX, USA","author":"L Bertelli","year":"2007","unstructured":"Bertelli L, Byun J, Manjunath BS: A variational approach to exploit prior information in object-background segregation: Application to retinal images. IEEE International Conference on Image Processing, San Antonio, TX, USA 2007., 6:"},{"key":"3098_CR31","volume-title":"IEEE International Conference on Image Processing, San Antonio, TX, USA","author":"N Vu","year":"2007","unstructured":"Vu N, Ghosh P, Manjunath BS: Retina layer segmentation and spatial alignment of antibody expression levels. IEEE International Conference on Image Processing, San Antonio, TX, USA 2007., 2:"},{"key":"3098_CR32","volume-title":"IEEE International Conference on Image Processing, San Diego, CA, USA","author":"L Bertelli","year":"2008","unstructured":"Bertelli L, Gosh P, Manjunath BS, Gibou F: Reference-based probabilistic segmentation as non-rigid registration using thin plate splines. IEEE International Conference on Image Processing, San Diego, CA, USA 2008."},{"key":"3098_CR33","volume-title":"Workshop on Bio-Image Informatics: Biological Imaging, Computer Vision and Data Mining, Santa Barbara, CA, USA","author":"K Kvilekval","year":"2008","unstructured":"Kvilekval K, Fedorov D, Obara B, Ruttenberg B, Manjunath BS, Singh AK: Bisque: bio-image semantic query user environment. Workshop on Bio-Image Informatics: Biological Imaging, Computer Vision and Data Mining, Santa Barbara, CA, USA 2008."}],"container-title":["BMC Bioinformatics"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1471-2105-10-368.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1186\/1471-2105-10-368\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1471-2105-10-368.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,3,17]],"date-time":"2024-03-17T12:07:56Z","timestamp":1710677276000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmcbioinformatics.biomedcentral.com\/articles\/10.1186\/1471-2105-10-368"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,11,1]]},"references-count":33,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2009,12]]}},"alternative-id":["3098"],"URL":"https:\/\/doi.org\/10.1186\/1471-2105-10-368","relation":{},"ISSN":["1471-2105"],"issn-type":[{"value":"1471-2105","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,11,1]]},"article-number":"368"}}