{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T22:49:33Z","timestamp":1761518973360},"reference-count":16,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2010,7,16]],"date-time":"2010-07-16T00:00:00Z","timestamp":1279238400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/2.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BMC Bioinformatics"],"published-print":{"date-parts":[[2010,12]]},"DOI":"10.1186\/1471-2105-11-380","type":"journal-article","created":{"date-parts":[[2010,7,20]],"date-time":"2010-07-20T16:38:41Z","timestamp":1279643921000},"source":"Crossref","is-referenced-by-count":47,"title":["R-Gada: a fast and flexible pipeline for copy number analysis in association studies"],"prefix":"10.1186","volume":"11","author":[{"given":"Roger","family":"Pique-Regi","sequence":"first","affiliation":[]},{"given":"Alejandro","family":"C\u00e1ceres","sequence":"additional","affiliation":[]},{"given":"Juan R","family":"Gonz\u00e1lez","sequence":"additional","affiliation":[]}],"member":"297","published-online":{"date-parts":[[2010,7,16]]},"reference":[{"issue":"9","key":"3837_CR1","doi-asserted-by":"publisher","first-page":"949","DOI":"10.1038\/ng1416","volume":"36","author":"AJ Iafrate","year":"2004","unstructured":"Iafrate AJ, Feuk L, Rivera MN, Listewnik ML, Donahoe PK, Qi Y, Scherer SW, Lee C: Detection of large-scale variation in the human genome. Nat Genet 2004, 36(9):949\u201351. 10.1038\/ng1416","journal-title":"Nat Genet"},{"issue":"7118","key":"3837_CR2","doi-asserted-by":"publisher","first-page":"444","DOI":"10.1038\/nature05329","volume":"444","author":"R Redon","year":"2006","unstructured":"Redon R, Ishikawa S, Fitch KR, Feuk L, Perry GH, Andrews TD, Fiegler H, Shapero MH, Carson AR, Chen W, Cho EK, Dallaire S, Freeman JL, Gonzalez JR, Gratacos M, et al.: Global variation in copy number in the human genome. Nature 2006, 444(7118):444\u201354. 10.1038\/nature05329","journal-title":"Nature"},{"issue":"7191","key":"3837_CR3","doi-asserted-by":"publisher","first-page":"56","DOI":"10.1038\/nature06862","volume":"453","author":"JM Kidd","year":"2008","unstructured":"Kidd JM, Cooper GM, Donahue WF, Hayden HS, Sampas N, Graves T, Hansen N, Teague B, Alkan C, Antonacci F, Haugen E, Zerr T, Yamada NA, Tsang P, Newman TL, Tuzun E, Cheng Z, Ebling HM, Tusneem N, David R, Gillett W, Phelps KA, Weaver M, Saranga D, Brand A, Tao W, Gustafson E, McKernan K, Chen L, Malig M, Smith JD, Korn JM, McCarroll SA, Altshuler DA, Peiffer DA, Dorschner M, Stamatoyannopoulos J, Schwartz D, Nickerson DA, Mullikin JC, Wilson RK, Bruhn L, Olson MV, Kaul R, Smith DR, Eichler EE: Mapping and sequencing of structural variation from eight human genomes. Nature 2008, 453(7191):56\u201364. 10.1038\/nature06862","journal-title":"Nature"},{"issue":"10","key":"3837_CR4","doi-asserted-by":"publisher","first-page":"1166","DOI":"10.1038\/ng.238","volume":"40","author":"S McCarroll","year":"2008","unstructured":"McCarroll S, Kuruvilla F, Korn J, Cawley S, Nemesh J, Wysoker A, Shapero M, de Bakker P, Maller J, Kirby A, Elliott A, Parkin M, Hubbell E, Webster T, Mei R, Veitch J, Collins P, Handsaker R, Lincoln S, Nizzari M, Blume J, Jones K, Rava R, Daly M, Gabriel S, Altshuler D: Integrated detection and population-genetic analysis of SNPs and copy number variation. Nat Genet 2008, 40(10):1166\u201374. 10.1038\/ng.238","journal-title":"Nat Genet"},{"issue":"7289","key":"3837_CR5","doi-asserted-by":"publisher","first-page":"704","DOI":"10.1038\/nature08516","volume":"464","author":"DF Conrad","year":"2010","unstructured":"Conrad DF, Pinto D, Redon R, Feuk L, Gokcumen O, Zhang Y, Aerts J, Andrews TD, Barnes C, Campbell P, Fitzgerald T, Hu M, Ihm CH, Kristiansson K, Macarthur DG, Macdonald JR, Onyiah I, Pang AWC, Robson S, Stirrups K, Valsesia A, Walter K, Wei J, Tyler-Smith C, Carter NP, Lee C, Scherer SW, Hurles ME: Origins and functional impact of copy number variation in the human genome. Nature 2010, 464(7289):704\u2013712. 10.1038\/nature08516","journal-title":"Nature"},{"issue":"7265","key":"3837_CR6","doi-asserted-by":"publisher","first-page":"747","DOI":"10.1038\/nature08494","volume":"461","author":"TA Manolio","year":"2009","unstructured":"Manolio TA, Collins FS, Cox NJ, Goldstein DB, Hindorff LA, Hunter DJ, McCarthy MI, Ramos EM, Cardon LR, Chakravarti A, Cho JH, Guttmacher AE, Kong A, Kruglyak L, Mardis E, Rotimi CN, Slatkin M, Valle D, Whittemore AS, Boehnke M, Clark AG, Eichler EE, Gibson G, Haines JL, Mackay TFC, McCarroll SA, Visscher PM: Finding the missing heritability of complex diseases. Nature 2009, 461(7265):747\u2013753. 10.1038\/nature08494","journal-title":"Nature"},{"issue":"3","key":"3837_CR7","doi-asserted-by":"publisher","first-page":"685","DOI":"10.1016\/j.ajhg.2007.12.010","volume":"82","author":"G Perry","year":"2008","unstructured":"Perry G, Ben-Dor A, Tsalenko A, Sampas N, Rodriguez-Revenga L, Tran C, Scheffer A, Steinfeld I, Tsang P, Yamada N, Park H, Kim J, Seo J, Yakhini Z, Laderman S, Bruhn L, Lee C: The fine-scale and complex architecture of human copy-number variation. Am J Hum Genet 2008, 82(3):685\u201395. 10.1016\/j.ajhg.2007.12.010","journal-title":"Am J Hum Genet"},{"issue":"3","key":"3837_CR8","doi-asserted-by":"publisher","first-page":"309","DOI":"10.1093\/bioinformatics\/btm601","volume":"24","author":"R Pique-Regi","year":"2008","unstructured":"Pique-Regi R, Monso-Varona J, Ortega A, Seeger RC, Triche TJ, Asgharzadeh S: Sparse representation and Bayesian detection of genome copy number alterations from microarray data. Bioinformatics 2008, 24(3):309\u201318. 10.1093\/bioinformatics\/btm601","journal-title":"Bioinformatics"},{"issue":"4","key":"3837_CR9","doi-asserted-by":"publisher","first-page":"557","DOI":"10.1093\/biostatistics\/kxh008","volume":"5","author":"AB Olshen","year":"2004","unstructured":"Olshen AB, Venkatraman ES, Lucito R, Wigler M: Circular binary segmentation for the analysis of array-based DNA copy number data. Biostatistics 2004, 5(4):557\u201372. 10.1093\/biostatistics\/kxh008","journal-title":"Biostatistics"},{"issue":"5","key":"3837_CR10","doi-asserted-by":"publisher","first-page":"353","DOI":"10.1093\/bfgp\/elp017","volume":"8","author":"L Winchester","year":"2009","unstructured":"Winchester L, Yau C, Ragoussis J: Comparing CNV detection methods for SNP arrays. Brief Funct Genomic Proteomic 2009, 8(5):353\u2013366. 10.1093\/bfgp\/elp017","journal-title":"Brief Funct Genomic Proteomic"},{"key":"3837_CR11","doi-asserted-by":"publisher","first-page":"211","DOI":"10.1162\/15324430152748236","volume":"1","author":"ME Tipping","year":"2001","unstructured":"Tipping ME: Sparse Bayesian learning and the relevance vector machine. J Mach Learn Res 2001, 1: 211\u2013244. 10.1162\/15324430152748236","journal-title":"J Mach Learn Res"},{"key":"3837_CR12","volume-title":"Theory and applications of correspondence analysis","author":"MJ Greenacre","year":"1984","unstructured":"Greenacre MJ: Theory and applications of correspondence analysis. Accademic Press, London; 1984."},{"key":"3837_CR13","volume-title":"Statistics in Medicine","author":"A Caceres","year":"2010","unstructured":"Caceres A, Basaga\u00f1a X, Gonzalez JR: Multiple correspondence discriminant analysis: An application to detect stratification in copy number variation. Statistics in Medicine 2010. [Accepted February 2010] [Accepted February 2010]"},{"key":"3837_CR14","doi-asserted-by":"publisher","first-page":"4084","DOI":"10.1093\/bioinformatics\/bti677","volume":"21","author":"H Willenbrock","year":"2005","unstructured":"Willenbrock H, Fridlyand J: A comparison study: applying segmentation to array CGH data for downstram analyses. Bioinformatics 2005, 21: 4084\u20134091. 10.1093\/bioinformatics\/bti677","journal-title":"Bioinformatics"},{"issue":"8","key":"3837_CR15","doi-asserted-by":"publisher","first-page":"904","DOI":"10.1038\/ng1847","volume":"38","author":"AL Price","year":"2006","unstructured":"Price AL, Patterson NJ, Plenge RM, Weinblatt ME, Shadick NA, Reich D: Principal components analysis corrects for stratification in genome-wide association studies. Nat Genet 2006, 38(8):904\u2013909. 10.1038\/ng1847","journal-title":"Nat Genet"},{"key":"3837_CR16","doi-asserted-by":"publisher","first-page":"1665","DOI":"10.1101\/gr.6861907","volume":"17","author":"K Wang","year":"2007","unstructured":"Wang K, Li M, Hadley D, Liu R, Glessner J, Grant S, Hakonarson H, M B: PennCNV: an integrated hidden Markov model designed for high-resolution copy number variation detection in whole-genome SNP genotyping data. Genome Research 2007, 17: 1665\u20131674. 10.1101\/gr.6861907","journal-title":"Genome Research"}],"container-title":["BMC Bioinformatics"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1471-2105-11-380.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1186\/1471-2105-11-380\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1471-2105-11-380.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,1,22]],"date-time":"2019-01-22T13:25:29Z","timestamp":1548163529000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmcbioinformatics.biomedcentral.com\/articles\/10.1186\/1471-2105-11-380"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,7,16]]},"references-count":16,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2010,12]]}},"alternative-id":["3837"],"URL":"https:\/\/doi.org\/10.1186\/1471-2105-11-380","relation":{},"ISSN":["1471-2105"],"issn-type":[{"value":"1471-2105","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,7,16]]},"article-number":"380"}}