{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,8,4]],"date-time":"2024-08-04T02:38:51Z","timestamp":1722739131348},"reference-count":52,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2010,1,26]],"date-time":"2010-01-26T00:00:00Z","timestamp":1264464000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/2.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BMC Bioinformatics"],"published-print":{"date-parts":[[2010,12]]},"DOI":"10.1186\/1471-2105-11-54","type":"journal-article","created":{"date-parts":[[2010,1,26]],"date-time":"2010-01-26T14:16:15Z","timestamp":1264515375000},"source":"Crossref","is-referenced-by-count":19,"title":["Towards realistic benchmarks for multiple alignments of non-coding sequences"],"prefix":"10.1186","volume":"11","author":[{"given":"Jaebum","family":"Kim","sequence":"first","affiliation":[]},{"given":"Saurabh","family":"Sinha","sequence":"additional","affiliation":[]}],"member":"297","published-online":{"date-parts":[[2010,1,26]]},"reference":[{"key":"3511_CR1","doi-asserted-by":"publisher","first-page":"D773","DOI":"10.1093\/nar\/gkm966","volume":"36","author":"D Karolchik","year":"2008","unstructured":"Karolchik D, Kuhn RM, Baertsch R, Barber GP, Clawson H, Diekhans M, Giardine B, Harte RA, Hinrichs AS, Hsu F, et al.: The UCSC Genome Browser Database: 2008 update. Nucleic Acids Res 2008, 36: D773\u2013779. 10.1093\/nar\/gkm966","journal-title":"Nucleic Acids Res"},{"key":"3511_CR2","doi-asserted-by":"publisher","first-page":"203","DOI":"10.1038\/nature06341","volume":"450","author":"AG Clark","year":"2007","unstructured":"Clark AG, Eisen MB, Smith DR, Bergman CM, Oliver B, Markow TA, Kaufman TC, Kellis M, Gelbart W, Iyer VN, et al.: Evolution of genes and genomes on the Drosophila phylogeny. Nature 2007, 450: 203\u2013218. 10.1038\/nature06341","journal-title":"Nature"},{"issue":"Unit 3","key":"3511_CR3","first-page":"7","volume":"Chapter 3","author":"V Simossis","year":"2003","unstructured":"Simossis V, Kleinjung J, Heringa J: An overview of multiple sequence alignment. Curr Protoc Bioinformatics 2003, Chapter 3(Unit 3):7.","journal-title":"Curr Protoc Bioinformatics"},{"key":"3511_CR4","doi-asserted-by":"publisher","first-page":"368","DOI":"10.1016\/j.sbi.2006.04.004","volume":"16","author":"RC Edgar","year":"2006","unstructured":"Edgar RC, Batzoglou S: Multiple sequence alignment. Curr Opin Struct Biol 2006, 16: 368\u2013373. 10.1016\/j.sbi.2006.04.004","journal-title":"Curr Opin Struct Biol"},{"key":"3511_CR5","doi-asserted-by":"publisher","first-page":"e123","DOI":"10.1371\/journal.pcbi.0030123","volume":"3","author":"C Notredame","year":"2007","unstructured":"Notredame C: Recent evolutions of multiple sequence alignment algorithms. PLoS Comput Biol 2007, 3: e123. 10.1371\/journal.pcbi.0030123","journal-title":"PLoS Comput Biol"},{"key":"3511_CR6","doi-asserted-by":"publisher","first-page":"143","DOI":"10.1007\/978-1-60327-159-2_7","volume":"452","author":"W Pirovano","year":"2008","unstructured":"Pirovano W, Heringa J: Multiple sequence alignment. Methods Mol Biol 2008, 452: 143\u2013161. full_text","journal-title":"Methods Mol Biol"},{"key":"3511_CR7","doi-asserted-by":"publisher","first-page":"2412","DOI":"10.1101\/gr.2800104","volume":"14","author":"M Blanchette","year":"2004","unstructured":"Blanchette M, Green ED, Miller W, Haussler D: Reconstructing large regions of an ancestral mammalian genome in silico. Genome Res 2004, 14: 2412\u20132423. 10.1101\/gr.2800104","journal-title":"Genome Res"},{"key":"3511_CR8","doi-asserted-by":"publisher","first-page":"721","DOI":"10.1142\/S0219720006002168","volume":"4","author":"L Chindelevitch","year":"2006","unstructured":"Chindelevitch L, Li Z, Blais E, Blanchette M: On the inference of parsimonious indel evolutionary scenarios. J Bioinform Comput Biol 2006, 4: 721\u2013744. 10.1142\/S0219720006002168","journal-title":"J Bioinform Comput Biol"},{"key":"3511_CR9","doi-asserted-by":"publisher","first-page":"265","DOI":"10.1007\/11732990_23","volume":"3909","author":"S Snir","year":"2006","unstructured":"Snir S, Pachter L: Phylogenetic profiling of insertions and deletions in vertebrate genomes. Research in Computational Molecular Biology, Proceedings 2006, 3909: 265\u2013280. full_text","journal-title":"Research in Computational Molecular Biology, Proceedings"},{"key":"3511_CR10","doi-asserted-by":"publisher","first-page":"3258","DOI":"10.1093\/bioinformatics\/btm402","volume":"23","author":"RK Bradley","year":"2007","unstructured":"Bradley RK, Holmes I: Transducers: an emerging probabilistic framework for modeling indels on trees. Bioinformatics 2007, 23: 3258\u20133262. 10.1093\/bioinformatics\/btm402","journal-title":"Bioinformatics"},{"key":"3511_CR11","doi-asserted-by":"publisher","first-page":"446","DOI":"10.1089\/cmb.2007.A006","volume":"14","author":"AB Diallo","year":"2007","unstructured":"Diallo AB, Makarenkov V, Blanchette M: Exact and heuristic algorithms for the Indel Maximum Likelihood Problem. J Comput Biol 2007, 14: 446\u2013461. 10.1089\/cmb.2007.A006","journal-title":"J Comput Biol"},{"key":"3511_CR12","doi-asserted-by":"publisher","first-page":"289","DOI":"10.1093\/bioinformatics\/btl578","volume":"23","author":"J Kim","year":"2007","unstructured":"Kim J, Sinha S: Indelign: a probabilistic framework for annotation of insertions and deletions in a multiple alignment. Bioinformatics 2007, 23: 289\u2013297. 10.1093\/bioinformatics\/btl578","journal-title":"Bioinformatics"},{"key":"3511_CR13","doi-asserted-by":"publisher","first-page":"874","DOI":"10.1093\/molbev\/msi090","volume":"22","author":"S Sinha","year":"2005","unstructured":"Sinha S, Siggia ED: Sequence turnover and tandem repeats in cis-regulatory modules in drosophila. Mol Biol Evol 2005, 22: 874\u2013885. 10.1093\/molbev\/msi090","journal-title":"Mol Biol Evol"},{"key":"3511_CR14","doi-asserted-by":"publisher","first-page":"105","DOI":"10.1038\/nature07175","volume":"455","author":"D Tian","year":"2008","unstructured":"Tian D, Wang Q, Zhang P, Araki H, Yang S, Kreitman M, Nagylaki T, Hudson R, Bergelson J, Chen JQ: Single-nucleotide mutation rate increases close to insertions\/deletions in eukaryotes. Nature 2008, 455: 105\u2013108. 10.1038\/nature07175","journal-title":"Nature"},{"key":"3511_CR15","doi-asserted-by":"publisher","first-page":"2469","DOI":"10.1002\/pro.5560071126","volume":"7","author":"K Mizuguchi","year":"1998","unstructured":"Mizuguchi K, Deane CM, Blundell TL, Overington JP: HOMSTRAD: a database of protein structure alignments for homologous families. Protein Sci 1998, 7: 2469\u20132471. 10.1002\/pro.5560071126","journal-title":"Protein Sci"},{"key":"3511_CR16","doi-asserted-by":"publisher","first-page":"127","DOI":"10.1002\/prot.20527","volume":"61","author":"JD Thompson","year":"2005","unstructured":"Thompson JD, Koehl P, Ripp R, Poch O: BAliBASE 3.0: latest developments of the multiple sequence alignment benchmark. Proteins 2005, 61: 127\u2013136. 10.1002\/prot.20527","journal-title":"Proteins"},{"key":"3511_CR17","doi-asserted-by":"publisher","first-page":"1267","DOI":"10.1093\/bioinformatics\/bth493","volume":"21","author":"I Van Walle","year":"2005","unstructured":"Van Walle I, Lasters I, Wyns L: SABmark--a benchmark for sequence alignment that covers the entire known fold space. Bioinformatics 2005, 21: 1267\u20131268. 10.1093\/bioinformatics\/bth493","journal-title":"Bioinformatics"},{"issue":"Suppl 3","key":"3511_CR18","doi-asserted-by":"publisher","first-page":"iii31","DOI":"10.1093\/bioinformatics\/bti1200","volume":"21","author":"RA Cartwright","year":"2005","unstructured":"Cartwright RA: DNA assembly with gaps (Dawg): simulating sequence evolution. Bioinformatics 2005, 21(Suppl 3):iii31\u201338. 10.1093\/bioinformatics\/bti1200","journal-title":"Bioinformatics"},{"key":"3511_CR19","doi-asserted-by":"publisher","first-page":"157","DOI":"10.1093\/bioinformatics\/14.2.157","volume":"14","author":"J Stoye","year":"1998","unstructured":"Stoye J, Evers D, Meyer F: Rose: generating sequence families. Bioinformatics 1998, 14: 157\u2013163. 10.1093\/bioinformatics\/14.2.157","journal-title":"Bioinformatics"},{"key":"3511_CR20","doi-asserted-by":"publisher","first-page":"1879","DOI":"10.1093\/molbev\/msp098","volume":"26","author":"W Fletcher","year":"2009","unstructured":"Fletcher W, Yang Z: INDELible: a flexible simulator of biological sequence evolution. Mol Biol Evol 2009, 26: 1879\u20131888. 10.1093\/molbev\/msp098","journal-title":"Mol Biol Evol"},{"key":"3511_CR21","doi-asserted-by":"publisher","first-page":"6","DOI":"10.1186\/1471-2105-5-6","volume":"5","author":"DA Pollard","year":"2004","unstructured":"Pollard DA, Bergman CM, Stoye J, Celniker SE, Eisen MB: Benchmarking tools for the alignment of functional noncoding DNA. BMC Bioinformatics 2004, 5: 6. 10.1186\/1471-2105-5-6","journal-title":"BMC Bioinformatics"},{"key":"3511_CR22","doi-asserted-by":"publisher","first-page":"278","DOI":"10.1186\/1471-2105-6-278","volume":"6","author":"MS Rosenberg","year":"2005","unstructured":"Rosenberg MS: Multiple sequence alignment accuracy and evolutionary distance estimation. BMC Bioinformatics 2005, 6: 278. 10.1186\/1471-2105-6-278","journal-title":"BMC Bioinformatics"},{"key":"3511_CR23","doi-asserted-by":"publisher","first-page":"314","DOI":"10.1080\/10635150500541730","volume":"55","author":"TH Ogdenw","year":"2006","unstructured":"Ogdenw TH, Rosenberg MS: Multiple sequence alignment accuracy and phylogenetic inference. Syst Biol 2006, 55: 314\u2013328. 10.1080\/10635150500541730","journal-title":"Syst Biol"},{"key":"3511_CR24","doi-asserted-by":"publisher","first-page":"376","DOI":"10.1186\/1471-2105-7-376","volume":"7","author":"DA Pollard","year":"2006","unstructured":"Pollard DA, Moses AM, Iyer VN, Eisen MB: Detecting the limits of regulatory element conservation and divergence estimation using pairwise and multiple alignments. BMC Bioinformatics 2006, 7: 376. 10.1186\/1471-2105-7-376","journal-title":"BMC Bioinformatics"},{"key":"3511_CR25","doi-asserted-by":"publisher","first-page":"298","DOI":"10.1101\/gr.6725608","volume":"18","author":"G Lunter","year":"2008","unstructured":"Lunter G, Rocco A, Mimouni N, Heger A, Caldeira A, Hein J: Uncertainty in homology inferences: assessing and improving genomic sequence alignment. Genome Res 2008, 18: 298\u2013309. 10.1101\/gr.6725608","journal-title":"Genome Res"},{"key":"3511_CR26","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1186\/1748-7188-3-7","volume":"3","author":"AW Dress","year":"2008","unstructured":"Dress AW, Flamm C, Fritzsch G, Grunewald S, Kruspe M, Prohaska SJ, Stadler PF: Noisy: identification of problematic columns in multiple sequence alignments. Algorithms Mol Biol 2008, 3: 7. 10.1186\/1748-7188-3-7","journal-title":"Algorithms Mol Biol"},{"key":"3511_CR27","doi-asserted-by":"publisher","first-page":"1380","DOI":"10.1093\/molbev\/msm060","volume":"24","author":"G Landan","year":"2007","unstructured":"Landan G, Graur D: Heads or tails: a simple reliability check for multiple sequence alignments. Mol Biol Evol 2007, 24: 1380\u20131383. 10.1093\/molbev\/msm060","journal-title":"Mol Biol Evol"},{"key":"3511_CR28","doi-asserted-by":"publisher","first-page":"2947","DOI":"10.1093\/bioinformatics\/btm404","volume":"23","author":"MA Larkin","year":"2007","unstructured":"Larkin MA, Blackshields G, Brown NP, Chenna R, McGettigan PA, McWilliam H, Valentin F, Wallace IM, Wilm A, Lopez R, et al.: Clustal W and Clustal X version 2.0. Bioinformatics 2007, 23: 2947\u20132948. 10.1093\/bioinformatics\/btm404","journal-title":"Bioinformatics"},{"key":"3511_CR29","doi-asserted-by":"publisher","first-page":"6","DOI":"10.1186\/1748-7188-3-6","volume":"3","author":"AR Subramanian","year":"2008","unstructured":"Subramanian AR, Kaufmann M, Morgenstern B: DIALIGN-TX: greedy and progressive approaches for segment-based multiple sequence alignment. Algorithms Mol Biol 2008, 3: 6. 10.1186\/1748-7188-3-6","journal-title":"Algorithms Mol Biol"},{"key":"3511_CR30","doi-asserted-by":"publisher","first-page":"286","DOI":"10.1093\/bib\/bbn013","volume":"9","author":"K Katoh","year":"2008","unstructured":"Katoh K, Toh H: Recent developments in the MAFFT multiple sequence alignment program. Brief Bioinform 2008, 9: 286\u2013298. 10.1093\/bib\/bbn013","journal-title":"Brief Bioinform"},{"key":"3511_CR31","doi-asserted-by":"publisher","first-page":"693","DOI":"10.1101\/gr.1960404","volume":"14","author":"N Bray","year":"2004","unstructured":"Bray N, Pachter L: MAVID: constrained ancestral alignment of multiple sequences. Genome Res 2004, 14: 693\u2013699. 10.1101\/gr.1960404","journal-title":"Genome Res"},{"key":"3511_CR32","doi-asserted-by":"publisher","first-page":"721","DOI":"10.1101\/gr.926603","volume":"13","author":"M Brudno","year":"2003","unstructured":"Brudno M, Do CB, Cooper GM, Kim MF, Davydov E, Green ED, Sidow A, Batzoglou S: LAGAN and Multi-LAGAN: efficient tools for large-scale multiple alignment of genomic DNA. Genome Res 2003, 13: 721\u2013731. 10.1101\/gr.926603","journal-title":"Genome Res"},{"key":"3511_CR33","doi-asserted-by":"publisher","first-page":"295","DOI":"10.1093\/bioinformatics\/btn630","volume":"25","author":"B Paten","year":"2009","unstructured":"Paten B, Herrero J, Beal K, Birney E: Sequence progressive alignment, a framework for practical large-scale probabilistic consistency alignment. Bioinformatics 2009, 25: 295\u2013301. 10.1093\/bioinformatics\/btn630","journal-title":"Bioinformatics"},{"key":"3511_CR34","doi-asserted-by":"publisher","first-page":"1321","DOI":"10.1126\/science.1098119","volume":"304","author":"G Bejerano","year":"2004","unstructured":"Bejerano G, Pheasant M, Makunin I, Stephen S, Kent WJ, Mattick JS, Haussler D: Ultraconserved elements in the human genome. Science 2004, 304: 1321\u20131325. 10.1126\/science.1098119","journal-title":"Science"},{"key":"3511_CR35","doi-asserted-by":"publisher","first-page":"1034","DOI":"10.1101\/gr.3715005","volume":"15","author":"A Siepel","year":"2005","unstructured":"Siepel A, Bejerano G, Pedersen JS, Hinrichs AS, Hou M, Rosenbloom K, Clawson H, Spieth J, Hillier LW, Richards S, et al.: Evolutionarily conserved elements in vertebrate, insect, worm, and yeast genomes. Genome Res 2005, 15: 1034\u20131050. 10.1101\/gr.3715005","journal-title":"Genome Res"},{"key":"3511_CR36","doi-asserted-by":"publisher","first-page":"e5","DOI":"10.1371\/journal.pcbi.0020005","volume":"2","author":"G Lunter","year":"2006","unstructured":"Lunter G, Ponting CP, Hein J: Genome-wide identification of human functional DNA using a neutral indel model. PLoS Comput Biol 2006, 2: e5. 10.1371\/journal.pcbi.0020005","journal-title":"PLoS Comput Biol"},{"key":"3511_CR37","doi-asserted-by":"publisher","first-page":"1335","DOI":"10.1101\/gr.178701","volume":"11","author":"CM Bergman","year":"2001","unstructured":"Bergman CM, Kreitman M: Analysis of conserved noncoding DNA in Drosophila reveals similar constraints in intergenic and intronic sequences. Genome Res 2001, 11: 1335\u20131345. 10.1101\/gr.178701","journal-title":"Genome Res"},{"key":"3511_CR38","doi-asserted-by":"publisher","first-page":"1576","DOI":"10.1093\/molbev\/msn103","volume":"25","author":"BG Hall","year":"2008","unstructured":"Hall BG: How well does the HoT score reflect sequence alignment accuracy? Mol Biol Evol 2008, 25: 1576\u20131580. 10.1093\/molbev\/msn103","journal-title":"Mol Biol Evol"},{"key":"3511_CR39","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.2517-6161.1977.tb01600.x","volume":"39","author":"AP Dempster","year":"1977","unstructured":"Dempster AP, Laird NM, Rubin DB: Maximum Likelihood from Incomplete Data Via EM Algorithm. Journal of the Royal Statistical Society Series B (Methodological) 1977, 39: 1\u201338.","journal-title":"Journal of the Royal Statistical Society Series B (Methodological)"},{"key":"3511_CR40","doi-asserted-by":"publisher","first-page":"708","DOI":"10.1101\/gr.1933104","volume":"14","author":"M Blanchette","year":"2004","unstructured":"Blanchette M, Kent WJ, Riemer C, Elnitski L, Smit AF, Roskin KM, Baertsch R, Rosenbloom K, Clawson H, Green ED, et al.: Aligning multiple genomic sequences with the threaded blockset aligner. Genome Res 2004, 14: 708\u2013715. 10.1101\/gr.1933104","journal-title":"Genome Res"},{"key":"3511_CR41","doi-asserted-by":"publisher","first-page":"e1000392","DOI":"10.1371\/journal.pcbi.1000392","volume":"5","author":"RK Bradley","year":"2009","unstructured":"Bradley RK, Roberts A, Smoot M, Juvekar S, Do J, Dewey C, Holmes I, Pachter L: Fast statistical alignment. PLoS Comput Biol 2009, 5: e1000392. 10.1371\/journal.pcbi.1000392","journal-title":"PLoS Comput Biol"},{"key":"3511_CR42","unstructured":"DrosOCB a high resolution map of conserved non coding sequences in Drosophila[\n                    http:\/\/arxiv.org\/abs\/0710.1570\n                    \n                  ]"},{"issue":"Suppl 1","key":"3511_CR43","doi-asserted-by":"publisher","first-page":"i344","DOI":"10.1093\/bioinformatics\/bti1042","volume":"21","author":"A Prakash","year":"2005","unstructured":"Prakash A, Tompa M: Statistics of local multiple alignments. Bioinformatics 2005, 21(Suppl 1):i344\u2013350. 10.1093\/bioinformatics\/bti1042","journal-title":"Bioinformatics"},{"key":"3511_CR44","doi-asserted-by":"publisher","first-page":"R124","DOI":"10.1186\/gb-2007-8-6-r124","volume":"8","author":"A Prakash","year":"2007","unstructured":"Prakash A, Tompa M: Measuring the accuracy of genome-size multiple alignments. Genome Biol 2007, 8: R124. 10.1186\/gb-2007-8-6-r124","journal-title":"Genome Biol"},{"key":"3511_CR45","first-page":"15","volume-title":"Pac Symp Biocomput","author":"G Landan","year":"2008","unstructured":"Landan G, Graur D: Local reliability measures from sets of co-optimal multiple sequence alignments. Pac Symp Biocomput 2008, 15\u201324."},{"key":"3511_CR46","doi-asserted-by":"publisher","first-page":"R225","DOI":"10.1186\/gb-2007-8-10-r225","volume":"8","author":"W Huang","year":"2007","unstructured":"Huang W, Nevins JR, Ohler U: Phylogenetic simulation of promoter evolution: estimation and modeling of binding site turnover events and assessment of their impact on alignment tools. Genome Biol 2007, 8: R225. 10.1186\/gb-2007-8-10-r225","journal-title":"Genome Biol"},{"key":"3511_CR47","doi-asserted-by":"publisher","first-page":"e1000299","DOI":"10.1371\/journal.pcbi.1000299","volume":"5","author":"X He","year":"2009","unstructured":"He X, Ling X, Sinha S: Alignment and prediction of cis-regulatory modules based on a probabilistic model of evolution. PLoS Comput Biol 2009, 5: e1000299. 10.1371\/journal.pcbi.1000299","journal-title":"PLoS Comput Biol"},{"key":"3511_CR48","doi-asserted-by":"publisher","first-page":"10557","DOI":"10.1073\/pnas.0409137102","volume":"102","author":"A Loytynoja","year":"2005","unstructured":"Loytynoja A, Goldman N: An algorithm for progressive multiple alignment of sequences with insertions. Proc Natl Acad Sci USA 2005, 102: 10557\u201310562. 10.1073\/pnas.0409137102","journal-title":"Proc Natl Acad Sci USA"},{"key":"3511_CR49","doi-asserted-by":"publisher","first-page":"e1000330","DOI":"10.1371\/journal.pgen.1000330","volume":"5","author":"J Kim","year":"2009","unstructured":"Kim J, He X, Sinha S: Evolution of regulatory sequences in 12 Drosophila species. PLoS Genet 2009, 5: e1000330. 10.1371\/journal.pgen.1000330","journal-title":"PLoS Genet"},{"key":"3511_CR50","unstructured":"AAA Drosophila website[\n                    http:\/\/rana.lbl.gov\/drosophila\/index.html\n                    \n                  ]"},{"key":"3511_CR51","doi-asserted-by":"publisher","first-page":"1586","DOI":"10.1093\/molbev\/msm088","volume":"24","author":"Z Yang","year":"2007","unstructured":"Yang Z: PAML 4: phylogenetic analysis by maximum likelihood. Mol Biol Evol 2007, 24: 1586\u20131591. 10.1093\/molbev\/msm088","journal-title":"Mol Biol Evol"},{"key":"3511_CR52","doi-asserted-by":"publisher","first-page":"368","DOI":"10.1007\/BF01734359","volume":"17","author":"J Felsenstein","year":"1981","unstructured":"Felsenstein J: Evolutionary trees from DNA sequences: a maximum likelihood approach. J Mol Evol 1981, 17: 368\u2013376. 10.1007\/BF01734359","journal-title":"J Mol Evol"}],"container-title":["BMC Bioinformatics"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1471-2105-11-54.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1186\/1471-2105-11-54\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1471-2105-11-54.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,1,22]],"date-time":"2019-01-22T07:46:11Z","timestamp":1548143171000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmcbioinformatics.biomedcentral.com\/articles\/10.1186\/1471-2105-11-54"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,1,26]]},"references-count":52,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2010,12]]}},"alternative-id":["3511"],"URL":"https:\/\/doi.org\/10.1186\/1471-2105-11-54","relation":{},"ISSN":["1471-2105"],"issn-type":[{"value":"1471-2105","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,1,26]]},"article-number":"54"}}