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For example, a collection of ChlP-seq experiments yields a compendium of peaks, each labeled with one or more associated DNA-binding proteins. Similarly, manually or automatically generated annotations of functional genomic elements, including <jats:italic>cis<\/jats:italic>-regulatory modules and protein-coding or RNA genes, can also be summarized as genomic segmentations.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results<\/jats:title>\n            <jats:p>We present a software toolkit called <jats:italic>Segtools<\/jats:italic> that simplifies and automates the exploration of genomic segmentations. The software operates as a series of interacting tools, each of which provides one mode of summarization. These various tools can be pipelined and summarized in a single HTML page. We describe the Segtools toolkit and demonstrate its use in interpreting a collection of human histone modification data sets and <jats:italic>Plasmodium falciparum<\/jats:italic> local chromatin structure data sets.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusions<\/jats:title>\n            <jats:p>Segtools provides a convenient, powerful means of interpreting a genomic segmentation.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1186\/1471-2105-12-415","type":"journal-article","created":{"date-parts":[[2011,10,26]],"date-time":"2011-10-26T18:33:30Z","timestamp":1319654010000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["Exploratory analysis of genomic segmentations with Segtools"],"prefix":"10.1186","volume":"12","author":[{"given":"Orion J","family":"Buske","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael M","family":"Hoffman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nadia","family":"Ponts","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karine G","family":"Le Roch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William Stafford","family":"Noble","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2011,10,26]]},"reference":[{"issue":"11","key":"4912_CR1","doi-asserted-by":"publisher","first-page":"1424","DOI":"10.1093\/bioinformatics\/btm096","volume":"23","author":"N Day","year":"2007","unstructured":"Day N, Hemmaplardh A, Thurman RE, Stamatoyannopoulos JA, Noble WS: Unsupervised segmentation of continuous genomic data. 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