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With hundreds of studies and thousands of expression profiles representing the majority of human cancers completed and in public databases, the challenge has been effectively accessing and using this wealth of data.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Description<\/jats:title>\n            <jats:p>To address this issue we have collected published human cancer gene expression datasets generated on the Affymetrix GeneChip platform, and carefully annotated those studies with a focus on providing accurate sample annotation. To facilitate comparison between datasets, we implemented a consistent data normalization and transformation protocol and then applied stringent quality control procedures to flag low-quality assays.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusion<\/jats:title>\n            <jats:p>The resulting resource, the GeneChip Oncology Database, is available through a publicly accessible website that provides several query options and analytical tools through an intuitive interface.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1186\/1471-2105-12-46","type":"journal-article","created":{"date-parts":[[2011,2,25]],"date-time":"2011-02-25T17:13:38Z","timestamp":1298654018000},"update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["GCOD - GeneChip Oncology Database"],"prefix":"10.1186","volume":"12","author":[{"given":"Fenglong","family":"Liu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joseph A","family":"White","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Corina","family":"Antonescu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel","family":"Gusenleitner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John","family":"Quackenbush","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2011,2,3]]},"reference":[{"key":"4421_CR1","volume-title":"Nucleic Acids Research","author":"Tanya Barrett","year":"2007","unstructured":"Barrett Tanya, Dennis B Troup, Stephen E Wilhite, Ledoux Pierre, Rudnev Dmitry, Evangelista Carlos, Irene F Kim, Soboleva Alexandra, Maxi Tomashevsky and Ron Edgar: Nucleic Acids Research. 2007. 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