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Our approach correlates theoretically predicted base triples with literature-based compilations and other actual occurrences in crystal structures. The use of \u2018fuzzy\u2019 search tolerances has enabled us to discover a number of triple interaction types that have not been previously recorded nor predicted theoretically.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusions<\/jats:title>\n            <jats:p>Comparative analyses of different ribosomal RNA structures reveal several conserved base triple motifs in 50S rRNA structures, indicating an important role in structural stabilization and ultimately RNA function.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1186\/1471-2105-12-s13-s2","type":"journal-article","created":{"date-parts":[[2011,12,2]],"date-time":"2011-12-02T05:05:24Z","timestamp":1322802324000},"update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Novel base triples in RNA structures revealed by graph theoretical searching methods"],"prefix":"10.1186","volume":"12","author":[{"given":"Mohd","family":"Firdaus-Raih","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anne-Marie","family":"Harrison","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"Willett","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter J","family":"Artymiuk","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2011,11,30]]},"reference":[{"key":"4918_CR1","doi-asserted-by":"publisher","first-page":"905","DOI":"10.1126\/science.289.5481.905","volume":"289","author":"N Ban","year":"2000","unstructured":"Ban N, Nissen P, Hansen J, Moore PB, Steitz TA: The complete atomic structure of the large ribosomal subunit at 2.4 Angstrom resolution. 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