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Decomposition of gene trees into embedded quartets (unrooted trees each with four taxa) is a convenient and statistically powerful technique to address this challenging problem. This approach was shown to be useful in several studies of completely sequenced microbial genomes.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results<\/jats:title>\n            <jats:p>We present here a web server that takes a collection of gene phylogenies, decomposes them into quartets, generates a Quartet Spectrum, and draws a split network. Users are also provided with various data download options for further analyses. Each gene phylogeny is to be represented by an assessment of phylogenetic information content, such as sets of trees reconstructed from bootstrap replicates or sampled from a posterior distribution. The Quartet Decomposition server is accessible at <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"http:\/\/quartets.uga.edu\" ext-link-type=\"uri\">http:\/\/quartets.uga.edu<\/jats:ext-link>.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusions<\/jats:title>\n            <jats:p>The Quartet Decomposition server presented here provides a convenient means to perform Quartet Decomposition analyses and will empower users to find statistically supported phylogenetic conflicts.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1186\/1471-2105-13-123","type":"journal-article","created":{"date-parts":[[2012,6,14]],"date-time":"2012-06-14T18:32:55Z","timestamp":1339698775000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Quartet decomposition server: a platform for analyzing phylogenetic trees"],"prefix":"10.1186","volume":"13","author":[{"given":"Fenglou","family":"Mao","sequence":"first","affiliation":[]},{"given":"David","family":"Williams","sequence":"additional","affiliation":[]},{"given":"Olga","family":"Zhaxybayeva","sequence":"additional","affiliation":[]},{"given":"Maria","family":"Poptsova","sequence":"additional","affiliation":[]},{"given":"Pascal","family":"Lapierre","sequence":"additional","affiliation":[]},{"given":"J Peter","family":"Gogarten","sequence":"additional","affiliation":[]},{"given":"Ying","family":"Xu","sequence":"additional","affiliation":[]}],"member":"297","published-online":{"date-parts":[[2012,6,7]]},"reference":[{"issue":"9","key":"5369_CR1","doi-asserted-by":"publisher","first-page":"711","DOI":"10.1038\/nrmicro1234","volume":"3","author":"CM Thomas","year":"2005","unstructured":"Thomas CM, Nielsen KM: Mechanisms of, and barriers to, horizontal gene transfer between bacteria. 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