{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T10:53:24Z","timestamp":1740135204501,"version":"3.37.3"},"reference-count":42,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2012,9,28]],"date-time":"2012-09-28T00:00:00Z","timestamp":1348790400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/2.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BMC Bioinformatics"],"published-print":{"date-parts":[[2012,12]]},"DOI":"10.1186\/1471-2105-13-251","type":"journal-article","created":{"date-parts":[[2012,9,30]],"date-time":"2012-09-30T07:53:34Z","timestamp":1348991614000},"source":"Crossref","is-referenced-by-count":10,"title":["The Process-Interaction-Model: a common representation of rule-based and logical models allows studying signal transduction on different levels of detail"],"prefix":"10.1186","volume":"13","author":[{"given":"Katrin","family":"Kolczyk","sequence":"first","affiliation":[]},{"given":"Regina","family":"Samaga","sequence":"additional","affiliation":[]},{"given":"Holger","family":"Conzelmann","sequence":"additional","affiliation":[]},{"given":"Sebastian","family":"Mirschel","sequence":"additional","affiliation":[]},{"given":"Carsten","family":"Conradi","sequence":"additional","affiliation":[]}],"member":"297","published-online":{"date-parts":[[2012,9,28]]},"reference":[{"issue":"4","key":"5709_CR1","doi-asserted-by":"publisher","first-page":"339","DOI":"10.1093\/bib\/bbl043","volume":"7","author":"D Gilbert","year":"2006","unstructured":"Gilbert D, Fuss H, Gu X, Orton R, Robinson S, Vyshemirsky V, Kurth MJ, Downes CS, Dubitzky W: Computational methodologies for modelling, analysis and simulation of signalling networks. Brief Bioinform 2006, 7(4):339\u2013353. \n                    http:\/\/dx.doi.org\/10.1093\/bib\/bbl043\n                    \n                   10.1093\/bib\/bbl043","journal-title":"Brief Bioinform"},{"issue":"5618","key":"5709_CR2","doi-asserted-by":"publisher","first-page":"445","DOI":"10.1126\/science.1083653","volume":"300","author":"T Pawson","year":"2003","unstructured":"Pawson T, Nash P: Assembly of cell regulatory systems through protein interaction domains. Science 2003, 300(5618):445\u2013452. \n                    http:\/\/dx.doi.org\/10.1126\/science.1083653\n                    \n                   10.1126\/science.1083653","journal-title":"Science"},{"issue":"7","key":"5709_CR3","doi-asserted-by":"publisher","first-page":"783","DOI":"10.1002\/bit.10842","volume":"84","author":"WS Hlavacek","year":"2003","unstructured":"Hlavacek WS, Faeder JR, Blinov ML, Perelson AS, Goldstein B: The complexity of complexes in signal transduction. Biotechnology and Bioengineering 2003, 84(7):783\u2013794. \n                    http:\/\/dx.doi.org\/10.1002\/bit.10842\n                    \n                   10.1002\/bit.10842","journal-title":"Biotechnology and Bioengineering"},{"issue":"4","key":"5709_CR4","doi-asserted-by":"publisher","first-page":"22","DOI":"10.1002\/cplx.20074","volume":"10","author":"JR Faeder","year":"2005","unstructured":"Faeder JR, Blinov ML, Goldstein B, Hlavacek WS: Rule-based modeling of biochemical networks. Complexity 2005, 10(4):22\u201341. \n                    http:\/\/dx.doi.org\/10.1002\/cplx.20074\n                    \n                   10.1002\/cplx.20074","journal-title":"Complexity"},{"issue":"2","key":"5709_CR5","doi-asserted-by":"publisher","first-page":"177","DOI":"10.1038\/nmeth.1546","volume":"8","author":"MW Sneddon","year":"2011","unstructured":"Sneddon MW, Faeder JR, Emonet T: Efficient modeling, simulation and coarse-graining of biological complexity with NFsim. Nat Methods 2011, 8(2):177\u2013183. \n                    http:\/\/dx.doi.org\/10.1038\/nmeth.1546\n                    \n                   10.1038\/nmeth.1546","journal-title":"Nat Methods"},{"key":"5709_CR6","doi-asserted-by":"publisher","first-page":"336","DOI":"10.1186\/1471-2105-8-336","volume":"8","author":"M Koschorreck","year":"2007","unstructured":"Koschorreck M, Conzelmann H, Ebert S, Ederer M, Gilles ED: Reduced modeling of signal transduction - a modular approach. BMC Bioinformatics 2007, 8: 336. \n                    http:\/\/dx.doi.org\/10.1186\/1471\u20132105\u20138-336\n                    \n                   10.1186\/1471-2105-8-336","journal-title":"BMC Bioinformatics"},{"key":"5709_CR7","doi-asserted-by":"publisher","first-page":"78","DOI":"10.1186\/1752-0509-2-78","volume":"2","author":"H Conzelmann","year":"2008","unstructured":"Conzelmann H, Fey D, Gilles ED: Exact model reduction of combinatorial reaction networks. BMC Syst Biol 2008, 2: 78. \n                    http:\/\/dx.doi.org\/10.1186\/1752\u20130509\u20132-78\n                    \n                   10.1186\/1752-0509-2-78","journal-title":"BMC Syst Biol"},{"issue":"5","key":"5709_CR8","doi-asserted-by":"publisher","first-page":"342","DOI":"10.1049\/iet-syb:20070081","volume":"2","author":"NM Borisov","year":"2008","unstructured":"Borisov NM, Chistopolsky AS, Faeder JR, Kholodenko BN: Domain-oriented reduction of rule-based network models. IET Syst Biol 2008, 2(5):342\u2013351. \n                    http:\/\/dx.doi.org\/10.1049\/iet-syb:20070081\n                    \n                   10.1049\/iet-syb:20070081","journal-title":"IET Syst Biol"},{"issue":"8","key":"5709_CR9","doi-asserted-by":"publisher","first-page":"e163","DOI":"10.1371\/journal.pcbi.0030163","volume":"3","author":"J Saez-Rodriguez","year":"2007","unstructured":"Saez-Rodriguez J, Simeoni L, Lindquist JA, Hemenway R, Bommhardt U, Arndt B, Haus UU, Weismantel R, Gilles ED, Klamt S, Schraven B: A logical model provides insights into T cell receptor signaling. PLoS Comput Biol 2007, 3(8):e163. \n                    http:\/\/dx.doi.org\/10.1371\/journal.pcbi.0030163\n                    \n                   10.1371\/journal.pcbi.0030163","journal-title":"PLoS Comput Biol"},{"issue":"8","key":"5709_CR10","doi-asserted-by":"publisher","first-page":"e1000438","DOI":"10.1371\/journal.pcbi.1000438","volume":"5","author":"R Samaga","year":"2009","unstructured":"Samaga R, Saez-Rodriguez J, Alexopoulos LG, Sorger PK, Klamt S: The logic of EGFR\/ErbB signaling: theoretical properties and analysis of high-throughput data. PLoS Comput Biol 2009, 5(8):e1000438. \n                    http:\/\/dx.doi.org\/10.1371\/journal.pcbi.1000438\n                    \n                   10.1371\/journal.pcbi.1000438","journal-title":"PLoS Comput Biol"},{"issue":"12","key":"5709_CR11","doi-asserted-by":"publisher","first-page":"e1000595","DOI":"10.1371\/journal.pcbi.1000595","volume":"5","author":"R Schlatter","year":"2009","unstructured":"Schlatter R, Schmich K, Vizcarra IA, Scheurich P, Sauter T, Borner C, Ederer M, Merfort I, Sawodny O: ON\/OFF and beyond\u2013a boolean model of apoptosis. PLoS Comput Biol 2009, 5(12):e1000595. \n                    http:\/\/dx.doi.org\/10.1371\/journal.pcbi.1000595\n                    \n                   10.1371\/journal.pcbi.1000595","journal-title":"PLoS Comput Biol"},{"key":"5709_CR12","doi-asserted-by":"publisher","first-page":"56","DOI":"10.1186\/1471-2105-7-56","volume":"7","author":"S Klamt","year":"2006","unstructured":"Klamt S, Saez-Rodriguez J, Lindquist JA, Simeoni L, Gilles ED: A methodology for the structural and functional analysis of signaling and regulatory networks. BMC Bioinformatics 2006, 7: 56. \n                    http:\/\/dx.doi.org\/10.1186\/1471\u20132105\u20137-56\n                    \n                   10.1186\/1471-2105-7-56","journal-title":"BMC Bioinformatics"},{"key":"5709_CR13","doi-asserted-by":"publisher","first-page":"2","DOI":"10.1186\/1752-0509-1-2","volume":"1","author":"S Klamt","year":"2007","unstructured":"Klamt S, Saez-Rodriguez J, Gilles ED: Structural and functional analysis of cellular networks with CellNetAnalyzer. BMC Syst Biol 2007, 1: 2. \n                    http:\/\/dx.doi.org\/10.1186\/1752\u20130509\u20131-2\n                    \n                   10.1186\/1752-0509-1-2","journal-title":"BMC Syst Biol"},{"key":"5709_CR14","doi-asserted-by":"publisher","first-page":"39","DOI":"10.1089\/cmb.2009.0121","volume":"17","author":"R Samaga","year":"2010","unstructured":"Samaga R, von Kamp A, Klamt S: Computing combinatorial intervention strategies and failure modes in signaling networks. J Comput Biol 2010, 17: 39\u201353. \n                    http:\/\/dx.doi.org\/10.1089\/cmb.2009.0121\n                    \n                   10.1089\/cmb.2009.0121","journal-title":"J Comput Biol"},{"key":"5709_CR15","doi-asserted-by":"publisher","first-page":"506","DOI":"10.1186\/1471-2105-7-506","volume":"7","author":"J Saez-Rodriguez","year":"2006","unstructured":"Saez-Rodriguez J, Mirschel S, Hemenway R, Klamt S, Gilles ED, Ginkel M: Visual setup of logical models of signaling and regulatory networks with ProMoT. BMC Bioinformatics 2006, 7: 506. \n                    http:\/\/dx.doi.org\/10.1186\/1471\u20132105\u20137-506\n                    \n                   10.1186\/1471-2105-7-506","journal-title":"BMC Bioinformatics"},{"issue":"5","key":"5709_CR16","doi-asserted-by":"publisher","first-page":"687","DOI":"10.1093\/bioinformatics\/btp029","volume":"25","author":"S Mirschel","year":"2009","unstructured":"Mirschel S, Steinmetz K, Rempel M, Ginkel M, Gilles ED: PROMOT: modular modeling for systems biology. Bioinformatics 2009, 25(5):687\u2013689. \n                    http:\/\/dx.doi.org\/10.1093\/bioinformatics\/btp029\n                    \n                   10.1093\/bioinformatics\/btp029","journal-title":"Bioinformatics"},{"key":"5709_CR17","doi-asserted-by":"publisher","first-page":"113","DOI":"10.1007\/978-1-59745-525-1_5","volume":"500","author":"JR Faeder","year":"2009","unstructured":"Faeder JR, Blinov ML, Hlavacek WS: Rule-based modeling of biochemical systems with BioNetGen. Methods Mol Biol 2009, 500: 113\u2013167. \n                    http:\/\/dx.doi.org\/10.1007\/978\u20131-59745\u2013525\u20131_5\n                    \n                   10.1007\/978-1-59745-525-1_5","journal-title":"Methods Mol Biol"},{"issue":"17","key":"5709_CR18","doi-asserted-by":"publisher","first-page":"3289","DOI":"10.1093\/bioinformatics\/bth378","volume":"20","author":"ML Blinov","year":"2004","unstructured":"Blinov ML, Faeder JR, Goldstein B, Hlavacek WS: BioNetGen: software for rule-based modeling of signal transduction based on the interactions of molecular domains. Bioinformatics 2004, 20(17):3289\u20133291. \n                    http:\/\/dx.doi.org\/10.1093\/bioinformatics\/bth378\n                    \n                   10.1093\/bioinformatics\/bth378","journal-title":"Bioinformatics"},{"key":"5709_CR19","doi-asserted-by":"publisher","first-page":"91","DOI":"10.1186\/1752-0509-2-91","volume":"2","author":"M Koschorreck","year":"2008","unstructured":"Koschorreck M, Gilles ED: ALC: automated reduction of rule-based models. BMC Syst Biol 2008, 2: 91. \n                    http:\/\/dx.doi.org\/10.1186\/1752\u20130509\u20132-91\n                    \n                   10.1186\/1752-0509-2-91","journal-title":"BMC Syst Biol"},{"key":"5709_CR20","first-page":"17","volume-title":"Computer Aided Verification, Proceedings, Volume 5643 of Lecture Notes in Computer Science","author":"J Krivine","year":"2009","unstructured":"Krivine J, Danos V, Benecke A: Modelling Epigenetic Information Maintenance: a Kappa Tutorial. In Computer Aided Verification, Proceedings, Volume 5643 of Lecture Notes in Computer Science. Edited by: Bouajjani A, Maler O. Springer-Verlag Berlin; 2009:17\u201332."},{"key":"5709_CR21","first-page":"89","volume-title":"Transactions on Computational Systems Biology VII, Volume 4230 of Lecture Notes in Computer Science","author":"M Blinov","year":"2006","unstructured":"Blinov M, Yang J, Faeder J, Hlavacek W: Graph Theory for Rule-Based Modeling of Biochemical Networks. In Transactions on Computational Systems Biology VII, Volume 4230 of Lecture Notes in Computer Science. Edited by: Priami C, Ing\u00f3lfsd\u00f3ttir A, Mishra B. Riis Nielson H: Springer Berlin \/Heidelberg; 2006:89\u2013106. \n                    http:\/\/dx.doi.org\/10.1007\/11905455_5"},{"issue":"6","key":"5709_CR22","doi-asserted-by":"publisher","first-page":"3268","DOI":"10.4049\/jimmunol.1000326","volume":"185","author":"A Nag","year":"2010","unstructured":"Nag A, Monine MI, Blinov ML, Goldstein B: A detailed mathematical model predicts that serial engagement of IgE-Fc epsilon RI complexes can enhance Syk activation in mast cells. J Immunol 2010, 185(6):3268\u20133276. \n                    http:\/\/dx.doi.org\/10.4049\/jimmunol.1000326\n                    \n                   10.4049\/jimmunol.1000326","journal-title":"J Immunol"},{"issue":"11","key":"5709_CR23","doi-asserted-by":"publisher","first-page":"e24808","DOI":"10.1371\/journal.pone.0024808","volume":"6","author":"F Geier","year":"2011","unstructured":"Geier F, Fengos G, Iber D: A computational analysis of the dynamic roles of talin, Dok1, and PIPKI for integrin activation. PLoS One 2011, 6(11):e24808. \n                    http:\/\/dx.doi.org\/10.1371\/journal.pone.0024808\n                    \n                   10.1371\/journal.pone.0024808","journal-title":"PLoS One"},{"issue":"10","key":"5709_CR24","doi-asserted-by":"publisher","first-page":"2779","DOI":"10.1039\/c1mb05077j","volume":"7","author":"LA Chylek","year":"2011","unstructured":"Chylek LA, Hu B, Blinov ML, Emonet T, Faeder JR, Goldstein B, Gutenkunst RN, Haugh JM, Lipniacki T, Posner RG, Yang J, Hlavacek WS: Guidelines for visualizing and annotating rule-based models. Mol Biosyst 2011, 7(10):2779\u20132795. \n                    http:\/\/dx.doi.org\/10.1039\/c1mb05077j\n                    \n                   10.1039\/c1mb05077j","journal-title":"Mol Biosyst"},{"key":"5709_CR25","doi-asserted-by":"publisher","first-page":"116","DOI":"10.1016\/j.jtbi.2011.11.014","volume":"295","author":"P Kocieniewski","year":"2012","unstructured":"Kocieniewski P, Faeder JR, Lipniacki T: The interplay of double phosphorylation and scaffolding in MAPK pathways. J Theor Biol 2012, 295: 116\u2013124. \n                    http:\/\/dx.doi.org\/10.1016\/j.jtbi.2011.11.014","journal-title":"J Theor Biol"},{"issue":"3 Pt 1","key":"5709_CR26","doi-asserted-by":"publisher","first-page":"031910","DOI":"10.1103\/PhysRevE.78.031910","volume":"78","author":"J Yang","year":"2008","unstructured":"Yang J, Monine MI, Faeder JR, Hlavacek WS: Kinetic Monte Carlo method for rule-based modeling of biochemical networks. Phys Rev E Stat Nonlin Soft Matter Phys 2008, 78(3 Pt 1):031910.","journal-title":"Phys Rev E Stat Nonlin Soft Matter Phys"},{"key":"5709_CR27","doi-asserted-by":"publisher","first-page":"404","DOI":"10.1186\/1471-2105-11-404","volume":"11","author":"J Colvin","year":"2010","unstructured":"Colvin J, Monine M, Gutenkunst R, Hlavacek W, Von Hoff D, Posner R: RuleMonkey: software for stochastic simulation of rule-based models. BMC Bioinformatics 2010, 11: 404. \n                    http:\/\/www.biomedcentral.com\/1471\u20132105\/11\/404\n                    \n                   10.1186\/1471-2105-11-404","journal-title":"BMC Bioinformatics"},{"key":"5709_CR28","doi-asserted-by":"publisher","first-page":"453","DOI":"10.1049\/iet-syb.2010.0015","volume":"4","author":"J Yang","year":"2010","unstructured":"Yang J, Meng X, Hlavacek WS: Rule-based modeling and simulation of biochemical systems with molecular finite automata. IET Syst Biol 2010, 4: 453\u2013466. 10.1049\/iet-syb.2010.0015","journal-title":"IET Syst Biol"},{"issue":"3","key":"5709_CR29","doi-asserted-by":"publisher","first-page":"437","DOI":"10.1016\/0022-5193(69)90015-0","volume":"22","author":"SA Kauffman","year":"1969","unstructured":"Kauffman SA: Metabolic stability and epigenesis in randomly constructed genetic nets. J Theor Biol 1969, 22(3):437\u2013467. 10.1016\/0022-5193(69)90015-0","journal-title":"J Theor Biol"},{"issue":"3","key":"5709_CR30","doi-asserted-by":"publisher","first-page":"563","DOI":"10.1016\/0022-5193(73)90247-6","volume":"42","author":"R Thomas","year":"1973","unstructured":"Thomas R: Boolean formalization of genetic control circuits. J Theor Biol 1973, 42(3):563\u2013585. 10.1016\/0022-5193(73)90247-6","journal-title":"J Theor Biol"},{"key":"5709_CR31","volume-title":"Biological Feedback","author":"R Thomas","year":"1990","unstructured":"Thomas R, D\u2019Ari R: Biological Feedback. Boca Raton Florida: CRC Press; 1990."},{"issue":"7-8","key":"5709_CR32","doi-asserted-by":"publisher","first-page":"593","DOI":"10.1093\/bioinformatics\/15.7.593","volume":"15","author":"L Mendoza","year":"1999","unstructured":"Mendoza L, Thieffry D, Alvarez-Buylla ER: Genetic control of flower morphogenesis in Arabidopsis thaliana: a logical analysis. Bioinformatics 1999, 15(7\u20138):593\u2013606.","journal-title":"Bioinformatics"},{"key":"5709_CR33","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/S0022-5193(03)00035-3","volume":"223","author":"R Albert","year":"2003","unstructured":"Albert R, Othmer HG: The topology of the regulatory interactions predicts the expression pattern of the segment polarity genes in Drosophila melanogaster. J Theor Biol 2003, 223: 1\u201318. 10.1016\/S0022-5193(03)00035-3","journal-title":"J Theor Biol"},{"key":"5709_CR34","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1186\/1752-0509-3-7","volume":"3","author":"TS Christensen","year":"2009","unstructured":"Christensen TS, Oliveira AP, Nielsen J: Reconstruction and logical modeling of glucose repression signaling pathways in Saccharomyces cerevisiae. BMC Syst Biol 2009, 3: 7. \n                    http:\/\/dx.doi.org\/10.1186\/1752\u20130509\u20133-7\n                    \n                   10.1186\/1752-0509-3-7","journal-title":"BMC Syst Biol"},{"key":"5709_CR35","doi-asserted-by":"publisher","first-page":"3253","DOI":"10.1039\/c1mb05261f","volume":"7","author":"A Ryll","year":"2011","unstructured":"Ryll A, Samaga R, Schaper F, Alexopoulos LG, Klamt S: Large-scale network models of IL-1 and IL-6 signalling and their hepatocellular specification. Mol Biosyst 2011, 7: 3253\u20133270. \n                    http:\/\/dx.doi.org\/10.1039\/c1mb05261f\n                    \n                   10.1039\/c1mb05261f","journal-title":"Mol Biosyst"},{"key":"5709_CR36","volume-title":"Fundamentals of Enzyme Kinetics","author":"A Cornish-Bowden","year":"2004","unstructured":"Cornish-Bowden A: Fundamentals of Enzyme Kinetics. London: Portland Press Ltd.; 2004."},{"issue":"9","key":"5709_CR37","first-page":"593","volume":"72","author":"M Karnaugh","year":"1953","unstructured":"Karnaugh M: The map method for synthesis of combinational logic circuits. Transactions of the American Institute of Electrical Engineers 1953, 72(9):593\u2013599.","journal-title":"Transactions of the American Institute of Electrical Engineers"},{"key":"5709_CR38","doi-asserted-by":"publisher","first-page":"127","DOI":"10.1145\/609784.609801","volume-title":"Proceedings of the 1952 ACM national meeting (Pittsburgh),","author":"EW Veitch","year":"1952","unstructured":"Veitch EW: A chart method for simplifying truth functions. In Proceedings of the 1952 ACM national meeting (Pittsburgh),. New York, NY USA: ACM, ACM \u201952; 1952:127\u2013133. \n                    http:\/\/doi.acm.org\/10.1145\/609784.609801"},{"issue":"5","key":"5709_CR39","doi-asserted-by":"publisher","first-page":"1417","DOI":"10.1002\/j.1538-7305.1956.tb03835.x","volume":"35","author":"EJ McCluskey","year":"1956","unstructured":"McCluskey EJ: Minimization of Boolean functions. Bell Syst Tech J 1956, 35(5):1417\u20131444.","journal-title":"Bell Syst Tech J"},{"issue":"9","key":"5709_CR40","doi-asserted-by":"publisher","first-page":"1169","DOI":"10.1093\/bioinformatics\/btg128","volume":"19","author":"M Ginkel","year":"2003","unstructured":"Ginkel M, Kremling A, Nutsch T, Rehner R, Gilles ED: Modular modeling of cellular systems with ProMoT\/Diva. Bioinformatics 2003, 19(9):1169\u20131176. \n                    http:\/\/bioinformatics.oxfordjournals.org\/content\/19\/9\/1169.abstract\n                    \n                   10.1093\/bioinformatics\/btg128","journal-title":"Bioinformatics"},{"issue":"3","key":"5709_CR41","doi-asserted-by":"publisher","first-page":"129","DOI":"10.1016\/j.tibs.2007.01.001","volume":"32","author":"CW Ward","year":"2007","unstructured":"Ward CW, Lawrence MC, Streltsov VA, Adams TE, McKern NM: The insulin and EGF receptor structures: new insights into ligand-induced receptor activation. Trends Biochem Sci 2007, 32(3):129\u2013137. \n                    http:\/\/dx.doi.org\/10.1016\/j.tibs.2007.01.001\n                    \n                   10.1016\/j.tibs.2007.01.001","journal-title":"Trends Biochem Sci"},{"key":"5709_CR42","first-page":"908","volume-title":"Winter Simulation Conference","author":"LA Harris","year":"2009","unstructured":"Harris LA, Hogg JS, Faeder JR: Compartmental rule-based modeling of biochemical systems. In Winter Simulation Conference, WSC \u201909. Winter Simulation Conference 2009, 908\u2013919. \n                    http:\/\/dl.acm.org\/citation.cfm?id=1995456.1995588"}],"container-title":["BMC Bioinformatics"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1471-2105-13-251.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1186\/1471-2105-13-251\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/1471-2105-13-251.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,1,22]],"date-time":"2019-01-22T04:46:24Z","timestamp":1548132384000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmcbioinformatics.biomedcentral.com\/articles\/10.1186\/1471-2105-13-251"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,9,28]]},"references-count":42,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2012,12]]}},"alternative-id":["5709"],"URL":"https:\/\/doi.org\/10.1186\/1471-2105-13-251","relation":{},"ISSN":["1471-2105"],"issn-type":[{"type":"electronic","value":"1471-2105"}],"subject":[],"published":{"date-parts":[[2012,9,28]]},"article-number":"251"}}